scholarly journals Immune Responses to Bovine Serum Albumin in Chicken Lines Divergently Selected for Antibody Responses to Sheep Red Blood Cells

1994 ◽  
Vol 73 (6) ◽  
pp. 825-835 ◽  
Author(s):  
H.K. PARMENTIER ◽  
R. SIEMONSMA ◽  
M.G.B. NIEUWLAND
2015 ◽  
Vol 2015 ◽  
pp. 1-4
Author(s):  
Kyoko Honne ◽  
Takao Nagashima ◽  
Masahiro Iwamoto ◽  
Toyomi Kamesaki ◽  
Seiji Minota

A 57-year-old man with rheumatoid arthritis developed severe anemia during treatment with adalimumab plus methotrexate. Cold agglutinin disease was diagnosed because haptoglobin was undetectable, cold agglutinin was positive (1 : 2048), and the direct Coombs test was positive (only to complement). Although the cold agglutinin titer was normalized (1 : 64) after treatment with prednisolone (0.7 mg/kg/day for two weeks), the patient’s hemoglobin did not increase above 8 g/dL. When cold agglutinins were reexamined using red blood cells suspended in bovine serum albumin, the titer was still positive at 1 : 1024. Furthermore, the cold agglutinin had a wide thermal amplitude, since the titer was 1 : 16 at 30°C and 1 : 1 at 37°C. This suggested that the cold agglutinin would show pathogenicity even at body temperature. After the dose of prednisolone was increased to 1 mg/kg/day, the patient’s hemoglobin rapidly returned to the normal range. The thermal amplitude test using red blood cells suspended in bovine serum albumin is more sensitive than the standard test for detecting pathogenic cold agglutinins.


2001 ◽  
Vol 80 (7) ◽  
pp. 894-900 ◽  
Author(s):  
H.K. Parmentier ◽  
S. Yousif Abuzeid ◽  
G. De Vries Reilingh ◽  
MG. Nieuwland ◽  
E.A.M. Graat

1981 ◽  
Vol 27 (9) ◽  
pp. 893-898
Author(s):  
M. C. Lajeunesse ◽  
P. Viens

The response to dinitrofluorobenzene (DNFB), bovine serum albumin (BSA), and sheep red blood cells (SRBC) was studied in CBA mice infected with Trypanosoma musculi at days ranging from 3 to 63 days of infection. DNFB contact sensitivity was normal. In 3-, 10-, and 15-day infected mice, anti-BSA hemagglutinating antibody titers were lower than in noninfected controls when determined after 21 days of BSA challenge, and were normal in sera collected after 10 and 14 days. In 14 day infected mice, anti-SRBC indirect plaque-forming cells (PFC) (per million of nucleated spleen cells and per total spleen) were strongly diminished, but anti-SRBC direct PFC were diminished only per million of nucleated spleen cells. In T. musculi recovered mice, the response to DNFB, BSA, and SRBC was normal.


2003 ◽  
Vol 82 (11) ◽  
pp. 1692-1700 ◽  
Author(s):  
BN Hangalapura ◽  
MG Nieuwland ◽  
G de Vries Reilingh ◽  
MJ Heetkamp ◽  
H van den Brand ◽  
...  

2011 ◽  
Vol 24 (5) ◽  
pp. 483-491 ◽  
Author(s):  
Seiichi Era ◽  
Masaru Sogami ◽  
Nobuhiro Uyesaka ◽  
Kazuo Kato ◽  
Masataka Murakami ◽  
...  

2020 ◽  
Vol 56 (90) ◽  
pp. 13959-13962
Author(s):  
Han Lin ◽  
Haofei Hong ◽  
Jinfeng Wang ◽  
Chen Li ◽  
Zhifang Zhou ◽  
...  

Rhamnose and sTn antigen were co-conjugated to bovine serum albumin (BSA) for cancer vaccine development. The immune responses against sTn have been significantly augmented with the involvement of Rha-specific antibodies to enhance antigen uptake.


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