Anti-inflammatory effect of preserved egg with simulated gastrointestinal digestion on LPS-stimulated RAW264.7 cells

Peptides DEDTQAMPFR (DR-10), MLGATSL (ML-7), SLSFASR (SR-7), and MSYSAGF (MF-7) derived from simulated gastrointestinal digestion of preserved egg white (SGD-PEW) exerted anti-inflammatory effects on DSS-induced mouse colitis.

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Anti-Inflammatory Effect of Asterias amurensis Fatty Acids through NF-��B and MAPK Pathways against LPS-Stimulated RAW264.7 Cells

Journal of Microbiology and Biotechnology ◽

10.4014/jmb.1802.03044 ◽

2018 ◽

Vol 28 (10) ◽

pp. 1635-1644 ◽

Cited By ~ 3

Author(s):

Chaiwat Monmai ◽

Seok Hyeon Go ◽

Il-shik Shin ◽

SangGuan You ◽

Dae-ok Kim ◽

...

Keyword(s):

Fatty Acids ◽

Raw264.7 Cells ◽

Asterias Amurensis ◽

Mapk Pathways ◽

Anti Inflammatory ◽

Inflammatory Effect

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Anti-Inflammatory Effect of the Extracts from Abeliophyllum distichum Nakai in LPS-Stimulated RAW264.7 Cells

Korean Journal of Plant Resources ◽

10.7732/kjpr.2014.27.3.209 ◽

2014 ◽

Vol 27 (3) ◽

pp. 209-214 ◽

Cited By ~ 7

Author(s):

Gwang Hun Park ◽

Jae Ho Park ◽

Hyun Ji Eo ◽

Hun Min Song ◽

Man Hyo Lee ◽

...

Keyword(s):

Raw264.7 Cells ◽

Anti Inflammatory ◽

Abeliophyllum Distichum ◽

Inflammatory Effect

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Anti-Inflammatory Effect of Sargassum patens C. Agardh Ethanol Extract in LPS-induced RAW264.7 Cells and Mouse Ear Edema

Microbiology and Biotechnology Letters ◽

10.4014/mbl.1610.10002 ◽

2017 ◽

Vol 45 (2) ◽

pp. 110-117 ◽

Cited By ~ 2

Author(s):

Min-Ji Kim ◽

Min-Ju Kim ◽

Koth Bong Woo Ri Kim ◽

Sun Hee Park ◽

Hyeun Deok Choi ◽

...

Keyword(s):

Ethanol Extract ◽

Raw264.7 Cells ◽

Ear Edema ◽

Mouse Ear ◽

Anti Inflammatory ◽

Sargassum Patens ◽

Mouse Ear Edema ◽

Inflammatory Effect

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MiR-155/GSK-3β mediates anti-inflammatory effect of Chikusetsusaponin IVa by inhibiting NF-κB signaling pathway in LPS-induced RAW264.7 cell

Scientific Reports ◽

10.1038/s41598-020-75358-1 ◽

2020 ◽

Vol 10 (1) ◽

Author(s):

Yi Xin ◽

Qin Yuan ◽

Chaoqi Liu ◽

Changcheng Zhang ◽

Ding Yuan

Keyword(s):

Signaling Pathway ◽

Mouse Liver ◽

Inflammatory Responses ◽

Biological Activities ◽

Raw264.7 Cells ◽

Inflammation Model ◽

Raw264.7 Cell ◽

Anti Inflammatory ◽

Gsk 3Β ◽

Inflammatory Effect

Abstract It has been demonstrated that Chikusetsusaponin IVa (CsIVa) possesses abundant biological activities. Herein, using LPS to establish acute inflammation model of mouse liver and cell line inflammation model, we investigated whether miR-155/GSK-3β regulated NF-κB signaling pathway, and CsIVa exerted anti-inflammatory effects by regulating miR-155/GSK-3β signaling pathway. Our results showed that LPS induced high expression of miR-155 and miR-155 promoted macrophage activation through GSK-3β. In addition, CsIVa inhibited inflammatory responses in LPS-induced mouse liver and RAW264.7 cells. Furthermore, we demonstrated that CsIVa improved the inflammatory response in LPS-induced RAW264.7 cells by inhibiting miR-155, increasing GSK-3β expression, and inhibiting NF-κB signaling pathway. In conclusion, our study reveals that CsIVa suppresses LPS-triggered immune response by miR-155/GSK-3β-NF-κB signaling pathway.

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