scholarly journals A NEW AGENT BOWEL CLEANSING BEFORE ENDOSCOPY - «COLOKIT»

2019 ◽  
Vol 18 (2) ◽  
pp. 27-32
Author(s):  
A. V. Galyaev ◽  
V. V. Veselov ◽  
R. I. Romanov ◽  
E. A. Poltorykhina ◽  
O. S. Ozerova

AIM: to evaluate the efficacy, safety and drug tolerance of «Colokit» for bowel cleansing before colonoscopy.PATIENTS AND METHODS: an open prospective non-randomised study of the quality of bowel cleansing was carried out in 30 patients (17 females, aged 26-72 years), who underwent diagnostic colonoscopy after using «Сolokit» (Mayoly Spindler, France) using two different regimes (recommended and alternative).RESULTS: the quality of the bowel cleansing was significantly better in patients after «Colokit» use in recommended regime vs alternative regime. No difference in subjective assessment of patients’ comfort during bowel preparation was found in both regimes. CONCLUSION: the «Colokit» agent provides good preparation and patients’ comfort and can be recommended for the bowel cleansing before colonoscopy.

2018 ◽  
pp. 25-30
Author(s):  
A. V. Galyaev ◽  
D. A. Mtvralashvili ◽  
O. V. Arkhipova ◽  
V. V. Veselov ◽  
S. S. Belous

AIM: to evaluate the effectiveness of bowel cleansing before colonoscopy using enteral nutrition agent «Nutridrink» as the single nutrient. MATERIALS AND METHODS: a prospective comparative study included 150 patients (83 females, aged 20-65 years), who underwent diagnostic colonoscopy. To assess the quality of bowel cleansing the Likert scale was used. Subjective assessment of patients' comfort was performed by patients on a 10-point visual scale (from 0 - «excellent» to 10 - «extremely negative»). RESULTS: the quality of colon cleansing before colonoscopy was significantly better in patients who got enteral nutrition, especially in comparison with patients with standard protein diet. Subjective assessment of comfort during cleansing was better in the group of patients who used Nutridrink as the only source of nutrition as well. CONCLUSION: use of enteral nutrition as a part of bowel cleansing before colonoscopy can replace the protein diet.


2019 ◽  
Vol 17 (4) ◽  
pp. 44-50
Author(s):  
Carolina Clavera Catalan ◽  
Estepa Laura ◽  
Navarrete Almudena ◽  
Milà MªAngels ◽  
Maynard Avonello

Background: Adequate bowel preparation is a prerequisite for colonoscopy. Good preparation improves adenoma detection and caecal intubation rates, and poor preparation can increase complications, cancellations, rebookings, and overall hospital stay. Methods: A retrospective descriptive study of all inpatient colonoscopies within inclusion criteria at Vall d'Hebron University Hospital from June 2016 to June 2017. This assessed the quality of bowel preparation using the simple, reliable Boston Bowel Preparation Scale (BBPS) and collected data on demographics and the referring unit. Results: Of 10 643 diagnostic and therapeutic colonoscopies performed, 854 (8%) were in inpatient studies, and 126 of these (14.8 %) were excluded. Of 728 patients included in the final analysis, bowel preparation was excellent in 18%, good in 45%, regular in 18% and poor in 19%. Of the 37% with inadequate preparation, 15% had to be repeated. Conclusions: Overall, hospital bowel preparations were insufficient. Proposals for improving the quality of bowel preparation included: recommending a waste-free diet for all new inpatients expected to undergo diagnostic colonoscopy; introducing a more tolerable polyethylene glycol laxative solution; and developing learning materials, such as simple written instructions for inpatients, a training plan for ward nurses and an infographic on the prerequisites for endoscopy.


2019 ◽  
Vol 07 (02) ◽  
pp. E216-E224 ◽  
Author(s):  
Madhav Desai ◽  
Venkat Nutalapati ◽  
Ajay Bansal ◽  
Daniel Buckles ◽  
John Bonino ◽  
...  

Abstract Introduction Smartphone-based applications (apps) have been used to improve the quality of bowel preparation (prep) but the success rates have been variable. We have performed a systematic review and meta-analysis to evaluate the impact of smartphone apps on bowel preparation. Methods Electronic databases (MEDLINE, Embase, CINAHL and Cochrane) were reviewed for eligible studies of smartphone apps versus standard education before colonoscopy. The following outcomes were analyzed: pooled rate of adequacy of bowel prep among both arms and Boston bowel preparation score (BBPS) when reported. Pooled analysis was reported as odds ratio (OR) or mean difference in random effect model with Review Manager 5.3 (P ≤ 0.05 for statistical significance). Results Six studies were eligible with smartphone app (810 patients) vs. standard education (855 patients, control group) for bowel prep. The smartphone app group had a higher proportion of adequate bowel prep compared to the control group: 87.5 % vs 77.5 % (five studies), pooled OR 2.67; 95 %CI 1.00 – 7.13 with P = 0.05. There was substantial heterogeneity in studies with I 2 = 78 %. When analysis was limited to randomized controlled trials (RCTs), smartphone app users had a numerically higher rate of bowel cleansing: 87.1 % vs 76.9 %; however, pooled OR was not statistically significant (OR 2.66, 95 %CI 0.92 – 7.69, P = 0.07). When studies using BBPS were evaluated (n = 3), smartphone app users had higher mean scores (better bowel prep) with a mean difference of 0.9 (95 %CI 0.5 – 1.3), which was statistically significant (P < 0.01). Conclusion The smartphone app is a novel educational tool that can assist in achieving adequate and better bowel cleansing before colonoscopy.


2016 ◽  
Vol 3 (3) ◽  
pp. 144-147 ◽  
Author(s):  
Wei-Fan Hsu ◽  
Cheng-Chao Liang ◽  
Cheng-Kuan Lin ◽  
Tzong-Hsi Lee ◽  
Chen-Shuan Chung

2010 ◽  
Vol 56 (2) ◽  
pp. 539-544 ◽  
Author(s):  
Chang Soo Eun ◽  
Dong Soo Han ◽  
Yil Sik Hyun ◽  
Joong Ho Bae ◽  
Hye Sun Park ◽  
...  

Author(s):  
Roberto Luiz KAISER-JÚNIOR ◽  
Luiz Gustavo DE-QUADROS ◽  
Mário FLAMINI-JÚNIOR ◽  
Mikaell Alexandre Gouvea FARIA ◽  
Juan Carlos Ochoa CAMPO ◽  
...  

ABSTRACT Background: Fifty-five percent of Americans aged 50-65 are submitted to colonoscopy. For over 65-year, this number increases to 64%. In Brazil, it is forecast that the population submitted to colonoscopy will grow, even though inadequate preparation is still a major problem. Aim: To analyze the quality of a new intestinal preparation technique, Aquanet EC-2000®, compared to oral Mannitol solution. Methods: This prospective longitudinal study enrolled 200 patients with indication for colonoscopy. The sample was randomly allocated to two groups of 100; one group received Aquanet EC-2000® to prepare for colonoscopy and the other Mannitol solution. The Boston scale was used to analyze the results. Results: As expected both preparations produced similar results with the bowel cleansing of the different regions of the colon being classified as Boston scale 3 (excellent) in most patients (p>0.05). Conclusion: The results of bowel preparation using Aquanet EC-2000® were similar to using Mannitol solution.


2019 ◽  
Vol 2019 ◽  
pp. 1-6 ◽  
Author(s):  
Chun-Xia Li ◽  
Yan Guo ◽  
Yang-Jie Zhu ◽  
Jian-Ru Zhu ◽  
Qian-Song Xiao ◽  
...  

Objective. This study was conducted to compare a lactulose oral solution with a polyethylene glycol (PEG) formulation for colonoscopy preparation using the following metrics: quality of cleansing, colonoscopy outcomes, patient/physician satisfaction, and patient tolerability. Methods. The enrolled patients were randomly divided into two groups and received a single 2 L dose of either PEG (PEG group) or lactulose (Lac group). The Boston Bowel Preparation Scale (BBPS) was used for assessing the cleansing quality of the bowel preparations. Patient tolerability and adverse events were obtained through the completion of questionnaires. Results. The lactulose oral solution showed superior bowel cleansing compared to PEG, as evidenced by higher BBPS scores in the Lac group for all segments of the colon (P<0.05). The detection rates of polyps and intestinal lesions in the Lac group (30.68% and 36.36%, respectively) were significantly higher than those in the PEG group (12.50% vs. 13.63%, respectively). For the degree of satisfaction, the Lac group had significantly higher scores compared to the PEG group, as evaluated by both the patients and endoscopist. PEG was associated with an increased incidence of nausea. There were no statistical differences between the groups in terms of vomiting, abdominal pain or fullness, dizziness, unfavorable palatability, dry mouth, palpitation, tinnitus, and tongue numbness. Conclusion. A single 2 L dose of a lactulose oral solution had higher efficacy, improved tolerability, and acceptable safety for bowel preparation when compared to the same volume of PEG. Thus, a lactulose oral solution may be a potential bowel-cleansing option for colonoscopy preparation.


2017 ◽  
Vol 55 (1) ◽  
pp. 36-43 ◽  
Author(s):  
T. Voiosu ◽  
Alina Tanţău ◽  
A. Voiosu ◽  
Andreea Benguş ◽  
Cristina Mocanu ◽  
...  

Abstract Background. Optimal bowel preparation is one of the most important factors affecting the quality of colonoscopy. Several patient-related factors are known to influence the quality of bowel cleansing but randomized trials in this area are lacking. We aimed to compare an individualized bowel prep strategy based on patient characteristics to a standard preparation regimen. Material and Methods. We conducted an endoscopist-blinded multicenter randomized control-trial. The Boston Bowel Prep Score (BBPS) was used to assess quality of bowel preparation and a 10 point visual analogue scale to assess patient comfort during bowel prep. Patients were randomised to either the standard regimens of split-dose 4L polyethylene-glycol (group A), split-dose sodium picosulphate/magnesium citrate (group B) or to either of the two depending on their responses to a 3-item questionnaire (individualized preparation, group C). Results. 185 patients were randomized during the study period and 143 patients were included in the final analysis. Patients in the individualized group had a median BBPS of 7 compared to a median of 6 in the standard group (p = 0.7). Also, there was no significant difference in patients’ comfort scores, irrespective of study group or laxative regimen. However, on multivariable analysis, a split-dose 4L polyethylene-glycol was an independent predictor for achieving a BBPS>6 (OR 3.7, 95% CI 1.4-9.8), regardless of patient-related factors. Conclusion. The choice of laxative seems to be more important than patient-related factors in predicting bowel cleansing. Comfort during bowel prep is not influenced by the type of strategy used.


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