scholarly journals Error-monitoring During Complex Probabilistic Association Learning in Adults with ADHD

Author(s):  
Gerathy Matthew ◽  
Rushby Jacqueline
2016 ◽  
Vol 136 (9) ◽  
pp. 1254-1260
Author(s):  
Reona Yamaguchi ◽  
Jun-ya Okamura ◽  
Kazunari Honda ◽  
Jin Oshima ◽  
Shintaro Saruwatari ◽  
...  

Author(s):  
Sabine Gosselke Berthelsen ◽  
Merle Horne ◽  
Yury Shtyrov ◽  
Mikael Roll

Abstract Many aspects of a new language, including grammar rules, can be acquired and accessed within minutes. In the present study, we investigate how initial learners respond when the rules of a novel language are not adhered to. Through spoken word-picture association-learning, tonal and non-tonal speakers were taught artificial words. Along with lexicosemantic content expressed by consonants, the words contained grammatical properties embedded in vowels and tones. Pictures that were mismatched with any of the words’ phonological cues elicited an N400 in tonal learners. Non-tonal learners only produced an N400 when the mismatch was based on a word's vowel or consonants, not the tone. The emergence of the N400 might indicate that error processing in L2 learners (unlike canonical processing) does not initially differentiate between grammar and semantics. Importantly, only errors based on familiar phonological cues evoked a mismatch-related response, highlighting the importance of phonological transfer in initial second language acquisition.


2021 ◽  
pp. 101490
Author(s):  
Johanna M. Boardman ◽  
Kate Porcheret ◽  
Jacob W. Clark ◽  
Thomas Andrillon ◽  
Anna W.T. Cai ◽  
...  

2016 ◽  
Vol 208 ◽  
pp. 365-372 ◽  
Author(s):  
Songhao Zhu ◽  
Chengjian Sun ◽  
Zhe Shi

2014 ◽  
Vol 45 (4) ◽  
pp. 841-854 ◽  
Author(s):  
A. J. Skilleter ◽  
C. S. Weickert ◽  
A. Vercammen ◽  
R. Lenroot ◽  
T. W. Weickert

Background.Brain-derived neurotrophic factor (BDNF) is an important regulator of synaptogenesis and synaptic plasticity underlying learning. However, a relationship between circulating BDNF levels and brain activity during learning has not been demonstrated in humans. Reduced brain BDNF levels are found in schizophrenia and functional neuroimaging studies of probabilistic association learning in schizophrenia have demonstrated reduced activity in a neural network that includes the prefrontal and parietal cortices and the caudate nucleus. We predicted that brain activity would correlate positively with peripheral BDNF levels during probabilistic association learning in healthy adults and that this relationship would be altered in schizophrenia.Method.Twenty-five healthy adults and 17 people with schizophrenia or schizo-affective disorder performed a probabilistic association learning test during functional magnetic resonance imaging (fMRI). Plasma BDNF levels were measured by enzyme-linked immunosorbent assay (ELISA).Results.We found a positive correlation between circulating plasma BDNF levels and brain activity in the parietal cortex in healthy adults. There was no relationship between plasma BDNF levels and task-related activity in the prefrontal, parietal or caudate regions in schizophrenia. A direct comparison of these relationships between groups revealed a significant diagnostic difference.Conclusions.This is the first study to show a relationship between peripheral BDNF levels and cortical activity during learning, suggesting that plasma BDNF levels may reflect learning-related brain activity in healthy humans. The lack of relationship between plasma BDNF and task-related brain activity in patients suggests that circulating blood BDNF may not be indicative of learning-dependent brain activity in schizophrenia.


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