Recombinant TgHSP70 Immunization Protects against Toxoplasma gondii Brain Cyst Formation by Enhancing Inducible Nitric Oxide Expression

Inducible nitric oxide synthase in innate immune cells is important for restricting cyst formation of Toxoplasma gondii in the brain but not required for the protective immune process to remove the cysts

Microbes and Infection ◽

10.1016/j.micinf.2017.12.004 ◽

2018 ◽

Vol 20 (4) ◽

pp. 261-266 ◽

Cited By ~ 6

Author(s):

Qila Sa ◽

Ashish Tiwari ◽

Eri Ochiai ◽

Jeremi Mullins ◽

Yasuhiro Suzuki

Keyword(s):

Nitric Oxide ◽

Toxoplasma Gondii ◽

Immune Cells ◽

Cyst Formation ◽

Innate Immune ◽

Innate Immune Cells ◽

Oxide Synthase ◽

The Brain ◽

Toxoplasma gondii: in vivo expression of BAG-5 and cyst formation is independent of TNF p55 receptor and inducible nitric oxide synthase functions

Microbes and Infection ◽

10.1016/s1286-4579(02)01537-x ◽

2002 ◽

Vol 4 (3) ◽

pp. 261-270 ◽

Cited By ~ 22

Author(s):

Neide M. Silva ◽

Wagner L. Tafuri ◽

Jacqueline I. Alvarez-Leite ◽

José R. Mineo ◽

Ricardo T. Gazzinelli

Keyword(s):

Nitric Oxide ◽

Toxoplasma Gondii ◽

Nitric Oxide Synthase ◽

Cyst Formation ◽

In Vivo Expression ◽

Oxide Synthase ◽

Reduced expression of the inducible nitric oxide synthase after infection with Toxoplasma gondii facilitates parasite replication in activated murine macrophages

International Journal for Parasitology ◽

10.1016/s0020-7519(03)00092-4 ◽

2003 ◽

Vol 33 (8) ◽

pp. 833-844 ◽

Cited By ~ 84

Author(s):

Carsten G.K. Lüder ◽

Michaela Algner ◽

Christine Lang ◽

Nadja Bleicher ◽

Uwe Groβ

Keyword(s):

Nitric Oxide ◽

Toxoplasma Gondii ◽

Nitric Oxide Synthase ◽

Murine Macrophages ◽

Parasite Replication ◽

Oxide Synthase ◽

Modified Protection against Toxoplasma gondii Lethal Infection and Brain Cyst Formation by Vaccination with SAG2 and SRS1.

Journal of Veterinary Medical Science ◽

10.1292/jvms.63.433 ◽

2001 ◽

Vol 63 (4) ◽

pp. 433-438 ◽

Cited By ~ 27

Author(s):

Masayuki MISHIMA ◽

Xuenan XUAN ◽

Akifumi SHIODA ◽

Yoshitaka OMATA ◽

Kozo FUJISAKI ◽

...

Keyword(s):

Toxoplasma Gondii ◽

Cyst Formation ◽

Brain Cyst ◽

Lethal Infection

Toxoplasma gondii: Evaluation of an intranasal vaccine using recombinant proteins against brain cyst formation in BALB/c mice

Experimental Parasitology ◽

10.1016/j.exppara.2007.10.002 ◽

2008 ◽

Vol 118 (3) ◽

pp. 386-392 ◽

Cited By ~ 30

Author(s):

M. Igarashi ◽

F. Kano ◽

K. Tamekuni ◽

R.Z. Machado ◽

I.T. Navarro ◽

...

Keyword(s):

Toxoplasma Gondii ◽

Recombinant Proteins ◽

Cyst Formation ◽

Brain Cyst ◽

Intranasal Vaccine

Impact of foetus and mother on IFN-γ-induced indoleamine 2,3-dioxygenase and inducible nitric oxide synthase expression in murine placenta following Toxoplasma gondii infection

International Journal for Parasitology ◽

10.1016/j.ijpara.2007.07.007 ◽

2008 ◽

Vol 38 (2) ◽

pp. 249-258 ◽

Cited By ~ 14

Author(s):

A PFAFF ◽

M MOUSLI ◽

A SENEGAS ◽

L MARCELLIN ◽

O TAKIKAWA ◽

...

Keyword(s):

Nitric Oxide ◽

Toxoplasma Gondii ◽

Nitric Oxide Synthase ◽

Indoleamine 2,3 Dioxygenase ◽

Ifn Γ ◽

Toxoplasma Gondii Infection ◽

Oxide Synthase ◽

Toxoplasma gondii Prevents Neuron Degeneration by Interferon-γ-Activated Microglia in a Mechanism Involving Inhibition of Inducible Nitric Oxide Synthase and Transforming Growth Factor-β1 Production by Infected Microglia

American Journal Of Pathology ◽

10.1016/s0002-9440(10)61191-1 ◽

2005 ◽

Vol 167 (4) ◽

pp. 1021-1031 ◽

Cited By ~ 49

Author(s):

Claudia Rozenfeld ◽

Rodrigo Martinez ◽

Sérgio Seabra ◽

Celso Sant'Anna ◽

J. Gabriel R. Gonçalves ◽

...

Keyword(s):

Nitric Oxide ◽

Growth Factor ◽

Toxoplasma Gondii ◽

Transforming Growth Factor ◽

Interferon Γ ◽

Transforming Growth Factor Β1 ◽

Neuron Degeneration ◽

Oxide Synthase ◽

Protection against Toxoplasma gondii brain cyst formation in mice immunized with Toxoplasma gondii cytoskeleton proteins and Lactobacillus casei as adjuvant

Veterinary Parasitology ◽

10.1016/j.vetpar.2008.11.017 ◽

2009 ◽

Vol 160 (3-4) ◽

pp. 311-315 ◽

Cited By ~ 11

Author(s):

Federico Martínez-Gómez ◽

Luis Francisco García-González ◽

Ricardo Mondragón-Flores ◽

Carlos Ramón Bautista-Garfias

Keyword(s):

Toxoplasma Gondii ◽

Lactobacillus Casei ◽

Cyst Formation ◽

Brain Cyst

High resistance to Toxoplasma gondii infection in inducible nitric oxide synthase (iNOS) knockout rats

iScience ◽

10.1016/j.isci.2021.103280 ◽

2021 ◽

pp. 103280

Author(s):

Zhen-Jie Wang ◽

Shao-Meng Yu ◽

Jiang-Mei Gao ◽

Peng Zhang ◽

Geoff Hide ◽

...

Keyword(s):

Nitric Oxide ◽

Toxoplasma Gondii ◽

Nitric Oxide Synthase ◽

High Resistance ◽

Toxoplasma Gondii Infection ◽

Oxide Synthase ◽

Deficiency in indoleamine-2, 3-dioxygenase induces upregulation of guanylate binding protein 1 and inducible nitric oxide synthase expression in the brain during cerebral infection with Toxoplasma gondii in genetically resistant BALB/c mice but not in genetically susceptible C57BL/6 mice

Microbes and Infection ◽

10.1016/j.micinf.2021.104908 ◽

2021 ◽

pp. 104908

Author(s):

Namrata Anand ◽

Jenny Lutshumba ◽

Megan Whitlow ◽

Mohamed H. Abdelaziz ◽

Rajesh Mani ◽

...

Keyword(s):

Nitric Oxide ◽

Toxoplasma Gondii ◽

Nitric Oxide Synthase ◽

Indoleamine 2 ◽

Cerebral Infection ◽

Oxide Synthase ◽

The Brain ◽

Guanylate Binding Protein ◽