scholarly journals Enhancement of Antigen Presentation by Deletion of Viral Immune Evasion Genes Prevents Lethal Cytomegalovirus Disease in Minor Histocompatibility Antigen-Mismatched Hematopoietic Cell Transplantation

2020 ◽  
Vol 10 ◽  
Author(s):  
Emin Gezinir ◽  
Jürgen Podlech ◽  
Kerstin M. Gergely ◽  
Sara Becker ◽  
Matthias J. Reddehase ◽  
...  
Keyword(s):  
Antigen Presentation ◽  
Cell Transplantation ◽  
Immune Evasion ◽  
Hematopoietic Cell Transplantation ◽  
Histocompatibility Antigen ◽  
Hematopoietic Cell ◽  
Minor Histocompatibility Antigen ◽  
Cytomegalovirus Disease ◽  
Viral Immune Evasion

scholarly journals Development of a Minor Histocompatibility Antigen Vaccine Regimen in the Canine Model of Hematopoietic Cell Transplantation

2015 ◽  
Vol 99 (10) ◽  
pp. 2083-2094 ◽  
Author(s):  
Steven Lawrence Rosinski ◽  
Brad Stone ◽  
Scott S. Graves ◽  
Deborah H. Fuller ◽  
Stephen C. De Rosa ◽  
...  
Keyword(s):  
Cell Transplantation ◽  
Hematopoietic Cell Transplantation ◽  
Canine Model ◽  
Histocompatibility Antigen ◽  
Hematopoietic Cell ◽  
Minor Histocompatibility Antigen ◽  
Vaccine Regimen ◽  
Antigen Vaccine ◽  
A Minor

scholarly journals Direct and indirect antigen presentation lead to deletion of donor-specific T cells after in utero hematopoietic cell transplantation in mice

Blood ◽  
2013 ◽  
Vol 121 (22) ◽  
pp. 4595-4602 ◽  
Author(s):  
Amar Nijagal ◽  
Chris Derderian ◽  
Tom Le ◽  
Erin Jarvis ◽  
Linda Nguyen ◽  
...  
Keyword(s):  
T Cells ◽  
Antigen Presentation ◽  
Cell Transplantation ◽  
Hematopoietic Cell Transplantation ◽  
De Novo ◽  
Tolerance Induction ◽  
In Utero ◽  
Effector T Cells ◽  
Hematopoietic Cell ◽  
Key Points

Key Points Tolerance induction after in utero hematopoietic cell transplantation involves both direct and indirect antigen presentation. Tolerance is achieved by deletion of effector T cells, which results in Treg enrichment without de novo Treg induction.

scholarly journals Cytomegalovirus disease before hematopoietic cell transplantation as a risk for complications after transplantation

2005 ◽  
Vol 11 (2) ◽  
pp. 136-148 ◽  
Author(s):  
Bettina C. Fries ◽  
Stanley R. Riddell ◽  
Hyung W. Kim ◽  
Lawrence Corey ◽  
Christine Dahlgren ◽  
...  
Keyword(s):  
Cell Transplantation ◽  
Hematopoietic Cell Transplantation ◽  
Hematopoietic Cell ◽  
Cytomegalovirus Disease
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