scholarly journals Phenotypic Expression of Autoimmunity in Children With Autoimmune Thyroid Disorders

2019 ◽  
Vol 10 ◽  
Author(s):  
Tommaso Aversa ◽  
Domenico Corica ◽  
Giuseppina Zirilli ◽  
Giovanni Battista Pajno ◽  
Giuseppina Salzano ◽  
...  
Keyword(s):  
Phenotypic Expression ◽  
Thyroid Disorders ◽  
Autoimmune Thyroid

scholarly journals Thyroid Disorders and COVID-19

Doctor Ru ◽  
2021 ◽  
Vol 20 (2) ◽  
pp. 6-10
Author(s):  
N.A. Petunina ◽  
◽  
Ya.A. Al Taravi ◽  
A.Yu. Surkova ◽  
N.S. Martirosyan ◽  
...  
Keyword(s):  
Thyroid Gland ◽  
Pulmonary Complications ◽  
Target Cells ◽  
Thyroid Disorders ◽  
Autoimmune Thyroid ◽  
Direct Invasion ◽  
Global Pandemic ◽  
Novel Coronavirus ◽  
Available Information ◽  
The Impact

Objective of the Review: To present the available information on the SARS-CoV-2 impact on thyroid gland (TG), impact from a thyroid pathology over COVID-19 morbidity and course, and management of patients with various thyroid pathologies and the novel coronavirus infection. Key Points. SARS-CoV-2 virus demonstrates exponential spread all over the globe and has caused a global pandemic of COVID-19 infection. Currently, the mechanism of non-pulmonary complications of SARS-CoV-2 and endocrine involvement is yet not clear. The impact from SARS-CoV-2 on TG can be a result of direct invasion of target cells by the virus or activation of immunise and inflammatory response.Changes in the pituitary-hypothalamic thyroid system can be caused by developing euthyroid pathology syndrome, glucocorticosteroid therapy, destructive thyroiditis. Manifestation of autoimmune thyroid disorders associated with COVID-19 cannot be ruled out. Conclusion. Currently there is no information on direct thyroid invasion by SARS-CoV-2; however the available results from trials and clinical observations demonstrate possible impact from coronavirus infections, in particular from SARS-CoV and SARS-CoV-2, on the pituitaryhypothalamic-thyroid system with development of various pathologies or a number of changes in thyroid hormone levels. Taking into account possible associations between thyroid dysfunction and prolonged hospitalisation, risk of deaths in hospital, and the association between thyrotoxicosis and atrial fibrillation and hypercoagulation, it is advisable to screen patients with severe COVID-19. Keywords: SARS-CoV-2, COVID-19, thyroid gland, nonsuppurative granulematous thyroiditis.

Infants born to mothers with autoimmune thyroid disorders: “Why” should we always measure anti-TSH-receptor antibodies

2020 ◽  
Vol 140 ◽  
pp. 104906
Author(s):  
Domenico Umberto De Rose ◽  
Rossella Iannotta ◽  
Francesca Gallini ◽  
Luca Maggio ◽  
Enrico Zecca ◽  
...  
Keyword(s):  
Tsh Receptor ◽  
Thyroid Disorders ◽  
Autoimmune Thyroid ◽  
Receptor Antibodies ◽  
Tsh Receptor Antibodies

scholarly journals Oxidative Stress and Immune System in Vitiligo and Thyroid Diseases

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Roberta Colucci ◽  
Federica Dragoni ◽  
Silvia Moretti
Keyword(s):  
Oxidative Stress ◽  
Immune System ◽  
Thyroid Autoimmunity ◽  
Thyroid Diseases ◽  
Thyroid Disorders ◽  
Autoimmune Thyroid ◽  
Dermatological Disease ◽  
Growing Body ◽  
And Oxidative Stress

Vitiligo is an acquired dermatological disease frequently associated with autoimmune thyroid disorders. Several theories have been proposed so far to unravel the complex vitiligo pathogenesis. Currently, the autocytotoxic and the autoimmune theories are the most accredited hypothesis, since they are sustained by several important clinical and experimental evidences. A growing body of evidences shows that autoimmunity and oxidative stress strictly interact to finally determine melanocyte loss. In this scenario, associated thyroid autoimmunity might play an active and important role in triggering and maintaining the depigmentation process of vitiligo.

Comorbidity of autoimmune thyroid disorders and psychiatric disorders during the postpartum period: a Danish nationwide register-based cohort study

2017 ◽  
Vol 48 (8) ◽  
pp. 1291-1298 ◽  
Author(s):  
V. Bergink ◽  
V. J. M. Pop ◽  
P. R. Nielsen ◽  
E. Agerbo ◽  
T. Munk-Olsen ◽  
...  
Keyword(s):  
Cohort Study ◽  
Psychiatric Disorders ◽  
Postpartum Period ◽  
Population Based ◽  
Thyroid Disorders ◽  
Autoimmune Thyroid ◽  
First Child ◽  
Bidirectional Association ◽  
First Onset ◽  
Comorbidity Index

AbstractBackgroundThe postpartum period is well-known risk period for the first onset of autoimmune thyroid disorders (AITDs) as well as first onset of psychiatric disorders. These two disorders are some of the most prevalent medical conditions postpartum, often misdiagnosed and disabling if left untreated. Our study was designed to explore the possible bidirectional association between AITDs and psychiatric disorders during the postpartum period.MethodsA population-based cohort study through linkage of Danish national registers, which comprised 312 779 women who gave birth to their first child during 1997–2010. We conducted Poisson regression analysis to estimate the incidence rate ratio (IRR) of psychiatric disorders among women with first-onset AITDs, the IRR of AITDs among women with first-onset psychiatric disorders as well as the overlap between these disorders using a comorbidity index.ResultsWomen with first-onset AITDs postpartum were more likely to have first-onset psychiatric disorders than women who did not have postpartum AITDs (IRR = 1.88, 95% confidence interval (CI): 1.25–2.81). Women with first-onset postpartum psychiatric disorders had a higher risk of AITDs than women with no psychiatric disorders (IRR = 2.16, 95% CI: 1.45–3.20). The comorbidity index 2 years after delivery was 2.26 (95% CI: 1.61–2.90), indicating a comorbidity between first-onset AITDs and psychiatric disorders.ConclusionsFirst-onset AITDs and psychiatric disorders co-occur in the postpartum period, which has relevance to further studies on the etiologies of these disorders and why childbirth in particular triggers the onset.

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