scholarly journals Rhesus Cytomegalovirus-Specific CD8+ Cytotoxic T Lymphocytes Do Not Become Functionally Exhausted in Chronic SIVmac239 Infection

2020 ◽  
Vol 11 ◽  
Author(s):  
Brandon C. Rosen ◽  
Nuria Pedreño-Lopez ◽  
Michael J. Ricciardi ◽  
Jason S. Reed ◽  
Jonah B. Sacha ◽  
...  
Keyword(s):  
T Lymphocytes ◽  
Cytotoxic T Lymphocytes ◽  
Rhesus Cytomegalovirus ◽  
Sivmac239 Infection

scholarly journals Effects of Cytotoxic T Lymphocytes (CTL) Directed against a Single Simian Immunodeficiency Virus (SIV) Gag CTL Epitope on the Course of SIVmac239 Infection

2002 ◽  
Vol 76 (20) ◽  
pp. 10507-10511 ◽  
Author(s):  
Todd M. Allen ◽  
Peicheng Jing ◽  
Briana Calore ◽  
Helen Horton ◽  
David H. O'Connor ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
T Lymphocytes ◽  
Immune Responses ◽  
Simian Immunodeficiency Virus ◽  
Cytotoxic T Lymphocytes ◽  
Ctl Epitope ◽  
Immunodeficiency Virus ◽  
The Impact ◽  
Sivmac239 Infection ◽  
Ctl Responses

ABSTRACT Vaccine-induced cytotoxic T lymphocytes (CTL) have been implicated in the control of virus replication in simian immunodeficiency virus (SIV)-challenged and simian-human immunodeficiency virus-challenged macaques. Therefore, we wanted to test the impact that vaccine-induced CTL responses against an immunodominant Gag epitope might have in the absence of other immune responses. By themselves, these strong CTL responses failed to control SIVmac239 replication.

Strategies for Tumor Elimination by Cytotoxic T Lymphocytes

1998 ◽  
Vol 18 (1-2) ◽  
pp. 47-54 ◽  
Author(s):  
Linda A. Sherman ◽  
Matthias Theobald ◽  
David Morgan ◽  
Javier Hernandez ◽  
Igor Bacik ◽  
...  
Keyword(s):  
T Lymphocytes ◽  
Cytotoxic T Lymphocytes

Morphological analysis of selective destruction of pancreatic beta-cells by cytotoxic T lymphocytes in NOD mice

Diabetes ◽  
1991 ◽  
Vol 40 (9) ◽  
pp. 1210-1217 ◽  
Author(s):  
M. Hayakawa ◽  
K. Yokono ◽  
M. Nagata ◽  
N. Hatamori ◽  
W. Ogawa ◽  
...  
Keyword(s):  
T Lymphocytes ◽  
Beta Cells ◽  
Cytotoxic T Lymphocytes ◽  
Pancreatic Beta Cells ◽  
Morphological Analysis ◽  
Nod Mice ◽  
Selective Destruction
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