Interaction between Perceived Action and Music Sequences in the Left Prefrontal Area

Many authors, examining personality changes after brain injury, have observed that lesions of the orbital surface of the frontal lobes are more frequently accompanied by emotional changes than lesions in any other part of the cortex. Amongst others, Schuster (1902), Berger (1923), Kleist (1931) and Rylander (1939), have called attention to this fact, and experimental work by Fulton and Ingraham (1929) on cats has established confirmatory evidence. Freeman and Watts (1942), in their study of leucotomized patients observed that, if only the lower quadrants of the white matter in the prefrontal area were cut, the results of leucotomy were better than when the cut was placed in the upper quadrants only. Groups of cases, in whom only the lower quadrants were sectioned, have also been reported on by Dax and Radley Smith (1943 and 1946), Reitman (1946) and Hofstatter et al (1945).

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The effects of combine treatment of memantine and donepezil on Alzheimer's Disease patients and its relationship with cerebral blood flow in the prefrontal area

International Journal of Geriatric Psychiatry ◽

10.1002/gps.4074 ◽

2014 ◽

Vol 29 (9) ◽

pp. 881-889 ◽

Cited By ~ 27

Author(s):

Tomoko Araki ◽

Rei Wake ◽

Tsuyoshi Miyaoka ◽

Kazunori Kawakami ◽

Michiharu Nagahama ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Blood Flow ◽

Cerebral Blood Flow ◽

Combine Treatment ◽

Prefrontal Area

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Simple and Effective Assessment of Posttraumatic Higher Brain Function Disorders with Special Reference to the Prefrontal Area

Minimally Invasive Neurosurgery and Multidisciplinary Neurotraumatology ◽

10.1007/4-431-28576-8_45 ◽

2007 ◽

pp. 293-309 ◽

Cited By ~ 1

Author(s):

Kenichi Uemura

Keyword(s):

Special Reference ◽

Brain Function ◽

Prefrontal Area ◽

Effective Assessment

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Movement Type Prediction before Its Onset Using Signals from Prefrontal Area: An Electrocorticography Study

BioMed Research International ◽

10.1155/2014/783203 ◽

2014 ◽

Vol 2014 ◽

pp. 1-9 ◽

Cited By ~ 11

Author(s):

Seokyun Ryun ◽

June Sic Kim ◽

Sang Hun Lee ◽

Sehyoon Jeong ◽

Sung-Phil Kim ◽

...

Keyword(s):

Motor Planning ◽

Elbow Flexion ◽

Beta Band ◽

Movement Onset ◽

Prefrontal Area ◽

Brain Responses ◽

Power Difference ◽

Sensorimotor Area ◽

Movement Type ◽

Specific Frequency

Power changes in specific frequency bands are typical brain responses during motor planning or preparation. Many studies have demonstrated that, in addition to the premotor, supplementary motor, and primary sensorimotor areas, the prefrontal area contributes to generating such responses. However, most brain-computer interface (BCI) studies have focused on the primary sensorimotor area and have estimated movements using postonset period brain signals. Our aim was to determine whether the prefrontal area could contribute to the prediction of voluntary movement types before movement onset. In our study, electrocorticography (ECoG) was recorded from six epilepsy patients while performing two self-paced tasks: hand grasping and elbow flexion. The prefrontal area was sufficient to allow classification of different movements through the area’s premovement signals (−2.0 s to 0 s) in four subjects. The most pronounced power difference frequency band was the beta band (13–30 Hz). The movement prediction rate during single trial estimation averaged 74% across the six subjects. Our results suggest that premovement signals in the prefrontal area are useful in distinguishing different movement tasks and that the beta band is the most informative for prediction of movement type before movement onset.

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Transcranial magnetic stimulation modulates left premotor cortex activity in facial expression recognition as a function of anxiety level

Translational Neuroscience ◽

10.2478/s13380-014-0226-6 ◽

2014 ◽

Vol 5 (3) ◽

Author(s):

Michela Balconi ◽

Ylenia Canavesio ◽

Roberta Finocchiaro

Keyword(s):

Transcranial Magnetic Stimulation ◽

Facial Expression ◽

Magnetic Stimulation ◽

Positive Emotions ◽

Premotor Cortex ◽

Anxiety Level ◽

Anxiety State ◽

High Anxiety ◽

Prefrontal Area

AbstractRecognition of emotional facial expressions is based on simulation and mirroring processes, and the premotor cortex is supposed to support this simulation mechanism. The role of this prefrontal area in processing emotional faces with different valence (anger, fear, happiness and neutral) was explored taking into account the effect of the lateralization model (more right-side activation for negative emotions; more left-side activation for positive emotions) of face processing and anxiety level (high vs low). High-frequency repetitive transcranial magnetic stimulation (rTMS, 10 Hz) was applied to the left prefrontal area to induce an increased activation response within the left premotor cortex. Twenty-nine subjects, who were divided into two different groups depending on their anxiety level (high/low anxiety; State-Trait-Anxiety Inventory (STAI), were asked to detect emotion / no emotion. Accuracy (AcI) and response times (RTs) were considered in response to the experimental conditions. A general significant increased performance was found in response to positive emotions in the case of left-side stimulation. Moreover, whereas high-anxiety subjects revealed a significant negative-valence bias in absence of stimulation, they showed a more significant AcI increasing and RTs decreasing in response to positive emotions in case of left premotor brain activation. The present results highlight the role of the premotor system for facial expression processing as a function of emotional type, supporting the existence of a valence-specific lateralized system within the prefrontal area. Finally, a sort of “restoring effect” induced by TMS was suggested for high-anxiety subjects.

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