Case Report: Prenatal and Postnatal Management for Fetal Bronchogenic Cysts During the COVID-19 Pandemic

Background: A fetal bronchogenic cyst (BC) is a rare congenital anomaly with an incidence of 0.147–0.238‰. The coronavirus disease 2019 (COVID-19) pandemic, as a particular situation, hindered pregnant women from receiving periodic prenatal checkups.Case Description: Until 34+6 weeks of gestation, a fetal case of the intrathoracic cyst was found by ultrasound examination. Further, MRI examination confirmed the diagnosis of the congenital mediastinal cystic lesion, probably a BC. Genetic testing was not conducted due to the COVID-19 pandemic. At 38+5 weeks of gestation with maternal COVID-19 testing negative, a live girl was delivered by cesarean section. Five months later, the child underwent bronchocystectomy, and the postoperative pathological lesions confirmed a (right upper mediastinum) BC.Conclusion: Herein, we reported the prenatal and postnatal management for a rare case of the congenital BC by multidisciplinary approaches during the COVID-19 pandemic. Fetal MRI and screening for fetal chromosomal abnormalities are especially recommended. This case contributes to the awareness that the COVID-19 pandemic interferes with regular follow-up schedules during pregnancy and may interfere with timely performed additional tests; which leads to more accurate genetic counseling. A combination of multidisciplinary approaches, including radiology, infection control, genetic counseling, obstetrics, and pediatric surgery, is pivotal for managing fetal BC during the COVID-19 pandemic.

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Follow-up in Patients With Non-invasive Prenatal Screening Failures: A Reflection on the Choice of Further Prenatal Diagnosis

Frontiers in Genetics ◽

10.3389/fgene.2021.666648 ◽

2021 ◽

Vol 12 ◽

Author(s):

Sha Liu ◽

Hongqian Liu ◽

Jianlong Liu ◽

Ting Bai ◽

Xiaosha Jing ◽

...

Keyword(s):

Genetic Counseling ◽

Prenatal Diagnosis ◽

Pregnant Women ◽

Prenatal Screening ◽

Chromosomal Abnormalities ◽

Detection Methods ◽

Chromosomal Microarray ◽

Chromosomal Microarray Analysis ◽

Non Invasive

BackgroundOur aim was to provide a theoretical basis for clinicians to conduct genetic counseling and choose further prenatal diagnosis methods for pregnant women who failed non-invasive prenatal screening (NIPS).MethodsA retrospective analysis was performed on pregnant women who had failed NIPS tests.ResultsAmong the 123,291 samples, 394 pregnant women did not obtain valid results due to test failures. A total of 378 pregnant women were available for follow-up, while 16 patients were lost to follow-up. Of these 378, 135 pregnant women chose further prenatal diagnosis through amniocentesis, and one case of dysplasia was recalled for postpartum chromosome testing. The incidence rate of congenital chromosomal abnormalities in those who failed the NIPS was 3.97% (15/378), which was higher than that of the chromosomal abnormalities in the common population (1.8%). Among the pregnant women who received prenatal diagnosis, the positive rates of chromosomal abnormalities in the chromosomal microarray analysis/copy number variation sequencing (CMA/CNV-seq) group and in the karyotyping group were 15.28 and 4.76%, respectively.ConclusionPrenatal diagnosis should be strongly recommended in posttest genetic counseling for pregnant women with NIPS failures. Further, high-resolution detection methods should be recommended for additional prenatal diagnoses.

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Video-Assisted Thoracoscopic Resection of Recurrent Intrapulmonary Bronchogenic Cyst after Thoracotomy

Innovations Technology and Techniques in Cardiothoracic and Vascular Surgery ◽

10.1097/imi.0000000000000057 ◽

2014 ◽

Vol 9 (2) ◽

pp. 142-144 ◽

Cited By ~ 2

Author(s):

Conor F. Hynes ◽

M. Blair Marshall

Keyword(s):

Bronchogenic Cyst ◽

Thoracoscopic Surgery ◽

Posterolateral Thoracotomy ◽

Thoracoscopic Resection ◽

Symptomatic Recurrence ◽

Video Assisted ◽

Pathologic Lesion ◽

Bronchogenic Cysts ◽

Video Assisted Thoracoscopic Surgery

Intrapulmonary bronchogenic cysts are typically treated surgically by lobectomy to completely excise the cyst to minimize risk for recurrence. Video-assisted thoracoscopic surgery is being used with increasing frequency to manage intrathoracic pathology. We present a patient who underwent resection of a bronchogenic cyst 20 years before. She developed a symptomatic recurrence, and video-assisted thoracoscopic surgery was used to lyse adhesions from her previous posterolateral thoracotomy and perform an intraparenchymal dissection to resect the pathologic lesion while sparing the remaining parenchyma of her right upper lobe. At 2 years of follow-up, the patient is without evidence of recurrence.

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A Rare Case of Allantoic Cyst with Patent Urachus in Fetus with a Microdeletion in 1q21.1q21.2 Region

Diagnostics ◽

10.3390/diagnostics11122332 ◽

2021 ◽

Vol 11 (12) ◽

pp. 2332

Author(s):

Alexandra Bouariu ◽

Ana Maria Scutelnicu ◽

Anca Marina Ciobanu ◽

Brîndușa Ana Cimpoca Raptis ◽

Andreea Elena Dumitru ◽

...

Keyword(s):

Rare Case ◽

Chromosomal Abnormalities ◽

Stone Formation ◽

First Trimester ◽

Patent Urachus ◽

Ultrasound Assessment ◽

Rare Malformation ◽

Tract Infections ◽

First Trimester Ultrasound

An allantoic cyst is a rare malformation with a frequency of 3 in 1,000,000 that may be seen antenatally by ultrasound assessment when the connection between the cloaca (future bladder) and the allantois fails to regress. A patent urachus that presents as a cyst (allantoic) is usually considered not to be associated with chromosomal abnormalities, but if it is not repaired after birth this leads to complications such as urinary tract infections and stone formation. We present a case of a fetus diagnosed with allantoic cyst at the first trimester ultrasound assessment at 12 weeks gestation. The follow up scans showed a decrease in size of the allantoic cyst with no other obvious major defects and, when invasive testing (amniocentesis with microarray analysis) was performed, a rare microdeletion, 1q21.1q21.2 was identified (1.82 Mb deletion).

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Management of Fetal Bronchogenic Lung Cysts: A Case Report and Short Review of Literature

Case Reports in Medicine ◽

10.1155/2010/751423 ◽

2010 ◽

Vol 2010 ◽

pp. 1-3 ◽

Cited By ~ 3

Author(s):

Ülkü Özmen Bayar ◽

Varîm Numanoğlu ◽

Sibel Bektaş ◽

Hakan Sade ◽

Duygu Tatlî

Keyword(s):

Case Report ◽

Congenital Malformations ◽

Bronchogenic Cyst ◽

Short Review ◽

Pathological Examination ◽

Review Of Literature ◽

Lung Cysts ◽

Cyst Aspiration ◽

Bronchogenic Cysts

Congenital malformations of the lung (CML) are rare with similar embryological and clinical spectra and could result in mortality if left untreated. Bronchogenic cysts are formed during the budding of the tracheal diverticula and ventral foregut in the embryological period. In this paper we want to present a case of bronchogenic cyst with continuous intrauterine cyst aspiration follow-up. After the baby birth was operated and the postoperative period was uneventful. The pathological examination revealed a bronchogenic cyst.

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Extrapericardial bronchogenic cyst associated with atrial fibrillation

MOJ Clinical & Medical Case Reports ◽

10.15406/mojcr.2021.11.00403 ◽

2021 ◽

Vol 11 (6) ◽

pp. 151-153

Author(s):

Andrei I Gritsiuta

Keyword(s):

Atrial Fibrillation ◽

Case Report ◽

Surgical Resection ◽

Successful Treatment ◽

Rare Case ◽

Bronchogenic Cyst ◽

Bronchogenic Cysts

Bronchogenic cysts are rare and usually asymptomatic. There are very few reports of bronchogenic cysts producingatrial fibrillation in the literature. We present a rare case of atrial fibrillation as a complication of a mediastinal bronchogenic cyst. To our knowledge, there have been only 13 cases of atrial fibrillation caused by a bronchogenic cyst published in the literature. As demonstrated by prior studies, surgical resection has been a successful treatment of the atrial fibrillation in this population. Our case report presents additional evidence to support the effectiveness of surgical resection in the treatment of bronchogenic cyst induced atrial fibrillation.

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A Rare Case of Mediastinal Bronchogenic Cyst Infected by Salmonella enteritidis

Case Reports in Pulmonology ◽

10.1155/2018/9121389 ◽

2018 ◽

Vol 2018 ◽

pp. 1-4 ◽

Cited By ~ 2

Author(s):

Jasleen Kaur ◽

Philip J. McDonald ◽

Ravinder D. Bhanot ◽

Reda A. Awali ◽

Sorabh Dhar ◽

...

Keyword(s):

Rare Case ◽

Salmonella Enteritidis ◽

Bronchogenic Cyst ◽

Lung Parenchyma ◽

Review Of The Literature ◽

Cyst Excision ◽

Adjacent Structures ◽

History Of ◽

Bronchogenic Cysts ◽

Culture Positive

Bronchogenic cysts are rare congenital malformations which arise from abnormal budding of the primitive tracheobronchial tube and can localize to either the mediastinum or lung parenchyma. They remain clinically silent in most adults unless they become infected or are large enough to compress adjacent structures. Infections involving bronchogenic cysts are often polymicrobial. Gram-positive, Gram-negative, and mycobacterial infections have been reported, though frequently a pathogen is not identified. We present the case of a 46-year-old female with known history of bronchogenic cyst who presented with suspected postobstructive pneumonia. She underwent cyst excision with culture positive for Salmonella enteritidis, an extremely rare finding on review of the literature. The patient recovered following a three-week course of antibiotics for extraintestinal salmonellosis.

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Abstract #110: Hemorrhagic Subdiaphragmatic Bronchogenic Cyst Mimicking an Adrenal Tumor: a Rare Case

Endocrine Practice ◽

10.1016/s1530-891x(20)42410-3 ◽

2015 ◽

Vol 21 ◽

pp. 6

Author(s):

Roy Guinto ◽

Michele Ledoux ◽

Alicia Williams ◽

Anthony Mark

Keyword(s):

Rare Case ◽

Adrenal Tumor ◽

Bronchogenic Cyst

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Modulation of carotid strain by statin therapy in atherosclerosis patients

VASA ◽

10.1024/0301-1526/a000596 ◽

2017 ◽

Vol 46 (2) ◽

pp. 108-115 ◽

Cited By ~ 3

Author(s):

Christian Alexander Schaefer ◽

Anna Katharina Blatzheim ◽

Sebastian Gorgonius Passon ◽

Kristin Solveig Pausewang ◽

Nadjib Schahab ◽

...

Keyword(s):

Statin Therapy ◽

Pulse Wave ◽

Ultrasound Examination ◽

Ankle Brachial Index ◽

Radial Strain ◽

Strain Analysis ◽

Duplex Ultrasound ◽

Strain Imaging ◽

The Common

Abstract. Background: The beneficial effect of statin therapy on the progress of atherosclerotic disease has been demonstrated by numerous studies. Vascular strain imaging is an arising method to evaluate arterial stiffness. Our study examined whether an influence of statin therapy on the vessel wall could be detected by vascular strain imaging. Patients and methods: 88 patients with recently detected atherosclerosis underwent an angiological examination including ankle-brachial index (ABI), pulse wave index (PWI), central puls ewave velocity and duplex ultrasound. Captures for vascular strain analysis were taken in B-mode during ultrasound examination of the common carotid artery and evaluated using a workstation equipped with a speckle tracking based software. A statin therapy was recommended and after six months a follow-up examination took place. Meanwhile, the non-adherence of a group of patients (N = 18) lead to a possibility to observe statin effects on the vascular strain. Results: In the statin non-adherent group the ABI decreased significantly to a still non-pathological level (1.2 ± 0.2 vs. 1.0 ± 0.2; p = 0.016) whereas it stagnated in the adherent group (1.0 ± 0.2 vs. 1.0 ± 0.2; p = 0.383). The PWI did not differ in the non-adherent group (180.5 ± 71.9 vs. 164.4 ± 75.8; p = 0.436) but under statin therapy it decreased significantly (261.8 ± 238.6 vs. 196.4 ± 137.4; p = 0.016). In comparison to the adherent group (4.2 ± 2.0 vs. 4.0 ± 1.8; p = 0.548) under statin therapy the radial strain decreased significantly in the non-adherent group (4.7 ± 2.0 vs. 3.3 ± 1.1; p = 0.014). Conclusions: Our findings reveal a beneficial influence of statin therapy on the arterial wall detected by vascular strain analysis.

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