scholarly journals Behavioral Effects of a Novel Benzofuranyl-Piperazine Serotonin-2C Receptor Agonist Suggest a Potential Therapeutic Application in the Treatment of Obsessive–Compulsive Disorder

2017 ◽  
Vol 8 ◽  
Author(s):  
Michelle M. Rodriguez ◽  
Carl Overshiner ◽  
J. David Leander ◽  
Xia Li ◽  
Denise Morrow ◽  
...  
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Receptor Agonist ◽  
Behavioral Effects ◽  
Therapeutic Application ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Serotonin 2C Receptor ◽  
Potential Therapeutic Application

Sumatriptan (5-HT 1D receptor agonist) does not exacerbate symptoms in obsessive compulsive disorder

1998 ◽  
Vol 140 (3) ◽  
pp. 365-370 ◽  
Author(s):  
Kamini L. Ho Pian ◽  
H. G. M. Westenberg ◽  
Harold J. G. M. van Megen ◽  
Johan A. den Boer
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Receptor Agonist ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

Behavioral effects of naloxone infusion in obsessive-compulsive disorder

1996 ◽  
Vol 40 (2) ◽  
pp. 154-156 ◽  
Author(s):  
David J. Keuler ◽  
Margaret Altemus ◽  
David Michelson ◽  
Benjamin Greenberg ◽  
Dennis L. Murphy
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Behavioral Effects ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

Psychostimulant-Induced Behavior as an Animal Model of Obsessive-Compulsive Disorder: An Ethological Approach to the Form of Compulsive Rituals

CNS Spectrums ◽  
2005 ◽  
Vol 10 (3) ◽  
pp. 191-202 ◽  
Author(s):  
David Eilam ◽  
Henry Szechtman
Keyword(s):  
Animal Model ◽  
Obsessive Compulsive Disorder ◽  
Rat Model ◽  
Receptor Agonist ◽  
Dopamine Receptor Agonist ◽  
Compulsive Behavior ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Dopaminergic Mechanisms ◽  
Motor Acts

AbstractRats treated chronically with the D2/D3, dopamine receptor agonist quinpirole show a pattern of behavior that meets a set of ethologically derived criteria of compulsive behavior in obsessive-compulsive disorder (OCD). Moreover, in both quinpirole-treated rats and OCD patients, the structure of compulsive rituals appear similar in being composed of relatively few motor acts that are organized in a flexible yet recurrent manner. In addition, the development of compulsive behavior in quinpirole-treated rats is attenuated by the OCD pharmacotherapeutic drug clomipramine. These similarities support the validity of quinpirole-treated rats as a psychostimulant-induced animal model of OCD. Considering that the induction of compulsive behavior in the rat model involves chronic hyperstimulation of dopamine receptors, this raises the possibility that dopaminergic mechanisms may play a role in OCD, at least in some subtypes of this disorder.

scholarly journals Self-Regulation of Anterior Insula with Real-Time fMRI and Its Behavioral Effects in Obsessive-Compulsive Disorder: A Feasibility Study

PLoS ONE ◽  
2015 ◽  
Vol 10 (8) ◽  
pp. e0135872 ◽  
Author(s):  
Korhan Buyukturkoglu ◽  
Hans Roettgers ◽  
Jens Sommer ◽  
Mohit Rana ◽  
Leonie Dietzsch ◽  
...  
Keyword(s):  
Real Time ◽  
Obsessive Compulsive Disorder ◽  
Feasibility Study ◽  
Self Regulation ◽  
Anterior Insula ◽  
Behavioral Effects ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

scholarly journals Correction: Self-Regulation of Anterior Insula with Real-Time fMRI and Its Behavioral Effects in Obsessive-Compulsive Disorder: A Feasibility Study

PLoS ONE ◽  
2015 ◽  
Vol 10 (12) ◽  
pp. e0145027 ◽  
Author(s):  
Korhan Buyukturkoglu ◽  
Hans Roettgers ◽  
Jens Sommer ◽  
Mohit Rana ◽  
Leonie Dietzsch ◽  
...  
Keyword(s):  
Real Time ◽  
Obsessive Compulsive Disorder ◽  
Feasibility Study ◽  
Self Regulation ◽  
Anterior Insula ◽  
Behavioral Effects ◽  
Obsessive Compulsive ◽  
Compulsive Disorder
Sign in / Sign up

Export Citation Format

Share Document