scholarly journals Mutual Influences between Nitric Oxide and Paraoxonase 1

Antioxidants ◽  
2019 ◽  
Vol 8 (12) ◽  
pp. 619
Author(s):  
Marta Marín ◽  
Carlos Moya ◽  
Salvador Máñez

One of the best consolidated paradigms in vascular pharmacology is that an uncontrolled excess of oxidizing chemical species causes tissue damage and loss of function in the endothelial and subendothelial layers. The fact that high-density lipoproteins play an important role in preventing such an imbalance is integrated into that concept, for which the expression and activity of paraoxonases is certainly crucial. The term paraoxonase (aryldialkyl phosphatase, EC 3.1.8.1) encompasses at least three distinct isoforms, with a wide variation in substrate affinity, cell and fluid localization, and biased expression of polymorphism. The purpose of this review is to determine the interactions that paraoxonase 1 has with nitric oxide synthase, its reaction product, nitric oxide (nitrogen monoxide, NO), and its derived reactive species generated in an oxidative medium, with a special focus on its pathological implications.

2017 ◽  
Vol 3 (3) ◽  
pp. 157
Author(s):  
M. Furutani ◽  
Y. Ohta ◽  
M. Nose

<p>Flat low-temperature two-stage flames were established on a Powling burner using rich diethyl-ether/ air or n-heptane/air mixtures, and nitrogen monoxide NO was added into the fuel-air mixtures with a concentration of 240 ppm. The temperature development and chemical-species histories, especially of NO, nitrogen dioxide NO<sub>2</sub> and hydrogen cyanide HCN were examined associated with an emission-spectrum measurement from the low-temperature flames. Nitrogen monoxide was consumed in the cool-flame region, where NO was converted to the NO<sub>2</sub>. The NO<sub>2</sub> generated, however, fell suddenly in the cool-flame degenerate region, in which the HCN superseded. In the blue-flame region the NO came out again and developed accompanied with remained HCN in the post blue-flame region. The NO seeding into the mixture intensified the blue-flame luminescence probably due to the cyanide increase.</p>


2002 ◽  
Vol 34 (6) ◽  
pp. A18
Author(s):  
T. Damy ◽  
P. Ratajczak ◽  
F. Marotte ◽  
J. Boczkowski ◽  
E. Robidel ◽  
...  

2008 ◽  
Vol 121 (24) ◽  
pp. 2553-2556 ◽  
Author(s):  
Xiu-ming GUO ◽  
Rong-hua TANG ◽  
Xin-yue QIN ◽  
Jun YANG ◽  
Guo-yuan CHEN

2018 ◽  
Vol 129 ◽  
pp. 227-236 ◽  
Author(s):  
Amanda A. Felizardo ◽  
Ivo S. Caldas ◽  
Andréa A.S. Mendonça ◽  
Reggiani V. Gonçalves ◽  
Fernanda L. Tana ◽  
...  

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