scholarly journals Emerging Contact-Killing Antibacterial Strategies for Developing Anti-Biofilm Dental Polymeric Restorative Materials

2020 ◽  
Vol 7 (3) ◽  
pp. 83 ◽  
Author(s):  
Heba Mitwalli ◽  
Rashed Alsahafi ◽  
Abdulrahman A. Balhaddad ◽  
Michael D. Weir ◽  
Hockin H. K. Xu ◽  
...  

Polymeric materials are the first choice for restoring tooth cavities, bonding tooth-colored fillings, sealing root canal systems, and many other dental restorative applications. However, polymeric materials are highly susceptible to bacterial attachment and colonization, leading to dental diseases. Many approaches have been investigated to minimize the formation of biofilms over polymeric restorative materials and at the tooth/material interfaces. Among them, contact-killing compounds have shown promising results to inhibit dental biofilms. Contact-killing compounds can be immobilized within the polymer structure, delivering a long-lasting effect with no leaching or release, thus providing advantages compared to release-based materials. This review discusses cutting-edge research on the development of contact-killing compounds in dental restorative materials to target oral pathogens. Contact-killing compounds in resin composite restorations, dental adhesives, root canal sealers, denture-based materials, and crown cements have all demonstrated promising antibacterial properties. Contact-killing restorative materials have been found to effectively inhibit the growth and activities of several oral pathogens related to dental caries, periodontal diseases, endodontic, and fungal infections. Further laboratory optimization and clinical trials using translational models are needed to confirm the clinical applicability of this new generation of contact-killing dental restorative materials.


1986 ◽  
Vol 24 (6-7) ◽  
pp. 592
Author(s):  
S.D. Meryon ◽  
R.M. Browne ◽  
P.F. Uphill ◽  
A.D. Cordery ◽  
R.F. Horsley




2003 ◽  
Vol 11 (3) ◽  
pp. 162-167 ◽  
Author(s):  
Linda Wang ◽  
Paulo Henrique Perlatti D'Alpino ◽  
Lawrence Gonzaga Lopes ◽  
José Carlos Pereira

A wide variety of dental products that are launched on the market becomes the correct selection of these materials a difficult task. Although the mechanical properties do not necessarily represent their actual clinical performance, they are used to guide the effects of changes in their composition or processing on these properties. Also, these tests might help somehow the clinician to choose once comparisons between former formulations and new ones, as well as, with the leading brand, are highlighted by manufactures. This paper presents a review of the most important laboratory tests. In this manner, the knowledge of these tests will provide a critical opinion related to the properties of different dental materials.





1982 ◽  
Vol 40 (2) ◽  
pp. 113-120 ◽  
Author(s):  
Kjeld Kr. Skjørland ◽  
Arne Hensten-Pettersen ◽  
Dag ørsta-Vik ◽  
Karl-Johan Söderholm


2021 ◽  
Vol 12 (4) ◽  
pp. 164
Author(s):  
MORTEZA SHARIFI ◽  
REZA KHODADADI ◽  
MOHAMMAD TAVAKOLI ◽  
MASOUMEH BEHDARVANDI


2019 ◽  
Vol 38 (2) ◽  
pp. 163-176 ◽  
Author(s):  
Abdul Samad KHAN ◽  
Mariam Raza SYED


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