Design Methodology of Passive In-Line Relays for Molecular Communication in Flow-Induced Microfluidic Channel

Molecular communication is a bioinspired communication that enables macro-scale, micro-scale and nano-scale devices to communicate with each other. The molecular communication system is prone to severe signal attenuation, dispersion and delay, which leads to performance degradation as the distance between two communicating devices increases. To mitigate these challenges, relays are used to establish reliable communication in microfluidic channels. Relay assisted molecular communication systems can also enable interconnection among various entities of the lab-on-chip for sharing information. Various relaying schemes have been proposed for reliable molecular communication systems, most of which lack practical feasibility. Thus, it is essential to design and develop relays that can be practically incorporated into the microfluidic channel. This paper presents a novel design of passive in-line relay for molecular communication system that can be easily embedded in the microfluidic channel and operate without external energy. Results show that geometric modification in the microfluidic channel can act as a relay and restore the degraded signal up-to 28%.

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Preliminary Studies on Flow Assisted Propagation of Fluorescent Microbeads in Microfluidic Channels for Molecular Communication Systems

Bio-inspired Information and Communication Technologies - Lecture Notes of the Institute for Computer Sciences, Social Informatics and Telecommunications Engineering ◽

10.1007/978-3-030-57115-3_26 ◽

2020 ◽

pp. 294-302

Author(s):

M. Gorkem Durmaz ◽

Abdurrahman Dilmac ◽

Berk Camli ◽

Elif Gencturk ◽

Z. Cansu Canbek Ozdil ◽

...

Keyword(s):

Communication Systems ◽

Microfluidic Channels ◽

Molecular Communication ◽

Molecular Communication Systems ◽

Fluorescent Microbeads

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Clock Synchronization for Mobile Molecular Communication Systems

IEEE Transactions on NanoBioscience ◽

10.1109/tnb.2020.3041631 ◽

2020 ◽

pp. 1-1

Author(s):

Li Huang ◽

Lin Lin ◽

Fuqiang Liu ◽

Hao Yan

Keyword(s):

Communication Systems ◽

Clock Synchronization ◽

Molecular Communication ◽

Molecular Communication Systems

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Information rate analysis of ASK-based molecular communication systems with feedback

Nano Communication Networks ◽

10.1016/j.nancom.2020.100339 ◽

2020 ◽

pp. 100339

Author(s):

Siavash Ghavami ◽

Raviraj Adve ◽

Farshad Lahouti

Keyword(s):

Communication Systems ◽

Information Rate ◽

Molecular Communication ◽

Rate Analysis ◽

Molecular Communication Systems

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Silicon-Quartz Microcapillary Opto-Fluidic Platform Obtained by CMOS-Compatible Die to Wafer 200 mm Dual Bonding Process

Proceedings ◽

10.3390/proceedings2131018 ◽

2018 ◽

Vol 2 (13) ◽

pp. 1018

Author(s):

Giuseppe Fiorentino ◽

Ben Jones ◽

Sophie Roth ◽

Edith Grac ◽

Murali Jayapala ◽

...

Keyword(s):

Adhesive Bonding ◽

System Analysis ◽

Quartz Substrate ◽

Microfluidic System ◽

Bonding Process ◽

Microfluidic Channels ◽

Fully Integrated ◽

Lab On Chip ◽

Human Blood Cells ◽

On Chip

A composite, capillary-driven microfluidic system suitable for transmitted light microscopy of cells (e.g., red and white human blood cells) is fabricated and demonstrated. The microfluidic system consists of a microchannels network fabricated in a photo-patternable adhesive polymer on a quartz substrate, which, by means of adhesive bonding, is then connected to a silicon microfluidic die (for processing of the biological sample) and quartz die (to form the imaging chamber). The entire bonding process makes use of a very low temperature budget (200 °C). In this demonstrator, the silicon die consists of microfluidic channels with transition structures to allow conveyance of fluid utilizing capillary forces from the polymer channels to the silicon channels and back to the polymer channels. Compared to existing devices, this fully integrated platform combines on the same substrate silicon microfluidic capabilities with optical system analysis, representing a portable and versatile lab-on-chip device.

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Microfluidic Channel Fabrication With Tailored Wall Roughness

ASME 2012 International Manufacturing Science and Engineering Conference ◽

10.1115/msec2012-7328 ◽

2012 ◽

Author(s):

Jing Ren ◽

Sriram Sundararajan

Keyword(s):

Flow Behavior ◽

Surface Texturing ◽

Microfluidic Channel ◽

Dip Coating ◽

Etch Depth ◽

Wall Roughness ◽

Random Surface ◽

Lab On Chip ◽

On Chip ◽

Autocorrelation Length

Realistic random roughness of channel surfaces is known to affect the fluid flow behavior in microscale fluidic devices. This has relevance particularly for applications involving non-Newtonian fluids, such as biomedical lab-on-chip devices. In this study, a surface texturing process was developed and integrated into microfluidic channel fabrication. The process combines colloidal masking and Reactive Ion Etching (RIE) for generating random surfaces with desired roughness parameters on the micro/nanoscale. The surface texturing process was shown to be able to tailor the random surface roughness on quartz. A Large range of particle coverage (around 6% to 67%) was achieved using dip coating and drop casting methods using a polystyrene colloidal solution. A relation between the amplitude roughness, autocorrelation length, etch depth and particle coverage of the processed surface was built. Experimental results agreed reasonably well with model predictions. The processed substrate was further incorporated into microchannel fabrication. Final device with designed wall roughness was tested and proved a satisfying sealing performance.

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