scholarly journals Preparation and Characterization of Perforated SERS Active Array for Particle Trapping and Sensitive Molecular Analysis

Biosensors ◽  
2019 ◽  
Vol 9 (3) ◽  
pp. 93 ◽  
Author(s):  
István Rigó ◽  
Miklós Veres ◽  
Tamás Váczi ◽  
Eszter Holczer ◽  
Orsolya Hakkel ◽  
...  

A gold-coated array of flow-through inverse pyramids applicable as substrate for entrapment and immobilization of micro-objects and for surface enhanced Raman spectroscopic measurements was fabricated using bulk micromachining techniques from silicon. Surface morphology, optical reflectance, immobilization properties, and surface enhanced Raman amplification of the array were modelled and characterized. It was found that the special perforated periodic 3D structure can be used for parallel particle and cell trapping and highly sensitive molecular analysis of the immobilized objects.

RSC Advances ◽  
2015 ◽  
Vol 5 (95) ◽  
pp. 77755-77759 ◽  
Author(s):  
Bo Yang ◽  
Xiaochun Chen ◽  
Renyong Liu ◽  
Bianhua Liu ◽  
Changlong Jiang

A highly sensitive and selective detection of As(iii) was reported by target induced aggregation of nanoparticles enhanced Raman spectroscopic technique.


2016 ◽  
Vol 2 (1) ◽  
Author(s):  
M. Rippa ◽  
R. Castagna ◽  
M. Pannico ◽  
P. Musto ◽  
E. Bobeico ◽  
...  

AbstractWe report on a novel procedure of fabrication to easily obtain highly reproducible nanocavities-shaped photonic crystals with strong plasmonic performances. Thus, we also report on the morphological and optical characterization of the obtained structures. They are classifiable as 2-layers (organic and inorganic) photonic crystals based on iso-Y-shaped nano-cavities. Such novel designed structures are compelling candidates for the development of highly sensitive biosensors due to their unique surface plasmon resonances (SPRs) and SPR enabled surface-enhanced Raman spectroscopy (SERS). The planar photonic crystal comprises a polymeric (ZEP520A) layer (thickness ~80 nm) sandwiched between a layer of gold (~50 nm thickness) and a glass substrate. For what concerns the cavities’ shape, iso-Y units are chosen on the basis of their third order nonlinearity and are coupled in hexagonal-based configuration to produce extended meta-structures. The substrates are functionalized with a probe made by a self-assembling monolayer (SAM) of 4-mercaptobenzoic acid (4-MBA). The average SERS Enhancement Factor >106 and SPR sensitivity of ~300 nm/RIU confirm that the proposed 2-layers iso-Y meta-structure is very suitable for high sensitive label-free plasmonic sensing.


2012 ◽  
Vol 41 ◽  
pp. 867-873 ◽  
Author(s):  
A.R.M. Radzol ◽  
Khuan Y. Lee ◽  
W. Mansor ◽  
S.R. Yahaya

Nano Express ◽  
2020 ◽  
Vol 1 (2) ◽  
pp. 020006 ◽  
Author(s):  
Maria Sole Zalaffi ◽  
Lucio Litti ◽  
Patrizia Canton ◽  
Moreno Meneghetti ◽  
Ligia Maria Moretto ◽  
...  

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