scholarly journals Differential Expression of Inflammatory Markers in Hypoglycemia Unawareness Associated with Type 1 Diabetes: A Case Report

2020 ◽  
Vol 11 (1) ◽  
pp. 17
Author(s):  
Yousef Al Zoubi ◽  
Bashair M. Mussa ◽  
Ankita Srivastava ◽  
Abdul Khader Mohammed ◽  
Elamin Abdelgadir ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Case Report ◽  
Differential Expression ◽  
Insulin Pump ◽  
Mrna Level ◽  
Insulin Injection ◽  
Hypoglycemia Unawareness ◽  
Tnf Α ◽  
Ifn Γ

The recurrence of hypoglycemic episodes leads to attenuation of the normal counter-regulatory mechanisms that are controlled by the hypothalamus, which results in hypoglycemia unawareness (HU). In this case report, we described for the first time the differential expression of TNF-α, IL-1β, IL-6, and IFN-γ in a blood sample that was taken from a 27-year-old patient with type 1 diabetes mellitus (T1DM) who was diagnosed with HU. The anti-diabetic regimen is currently based on insulin injection, but the patient is planning to start the use of an insulin pump to have better control of glucose levels. Our results showed a trend toward an increase in the expression of IL-1β, IL-6, and IFN-γ in T1DM patient with HU. However, the mRNA level of TNF-α showed a significant decrease. These observations suggest that systemic inflammation could be an underlying cause of HU.

scholarly journals Euglycemic Diabetic Ketoacidosis in Type 1 Diabetes on Insulin Pump, with Acute Appendicitis: A Case Report

2021 ◽  
Vol 5 (3) ◽  
pp. 296-298
Author(s):  
Brian Thompson ◽  
Anthony Kitchen
Keyword(s):  
Type 1 Diabetes ◽  
Case Report ◽  
Acute Appendicitis ◽  
Diabetic Ketoacidosis ◽  
Insulin Pump ◽  
Point Of Care ◽  
Altered Mental Status ◽  
History Of ◽  
Euglycemic Diabetic Ketoacidosis

Introduction: Recently, euglycemic diabetic ketoacidosis has been an increasing topic of discussion within emergency medicine literature. Euglycemic diabetic ketoacidosis can easily be missed, as a normal point-of-care glucose often mistakenly precludes the work-up of diabetic ketoacidosis. Case Report: A 16-year-old female with a past medical history of type 1 diabetes presented to the emergency department with altered mental status, vomiting, and abdominal pain. She was diagnosed with euglycemic diabetic ketoacidosis. Conclusion: Reported cases of euglycemic diabetic ketoacidosis are most frequently attributed to sodium glucose cotransporter-2 inhibitors, but other potential causes have been discussed in the literature. In this patient, a starvation state with continued insulin use in the setting of acute appendicitis led to her condition.

scholarly journals An unusual use of personal insulin pump by a patient with type 1 diabetes on a ketogenic diet — a case report

2019 ◽  
Vol 8 (4) ◽  
pp. 223-226
Author(s):  
Hanna Kwiendacz ◽  
Magdalena Domek ◽  
Katarzyna Nabrdalik ◽  
Anna Maj-Podsiadło ◽  
Magdalena Marcisz ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Case Report ◽  
Ketogenic Diet ◽  
Insulin Pump

scholarly journals TNF-α and IFN-γ gene variation and genetic susceptibility to type 1 diabetes and its microangiopathic complications

2014 ◽  
Vol 13 (1) ◽  
Author(s):  
Javad Tavakkoly Bazzaz ◽  
Mahsa M Amoli ◽  
Zahra Taheri ◽  
Bagher Larijani ◽  
Vera Pravica ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Genetic Susceptibility ◽  
Gene Variation ◽  
Tnf Α ◽  
Ifn Γ

scholarly journals Rapid Desensitization for Insulin Allergy in Type 1 Diabetes Using an Insulin Pump: A Case Report and Literature Review

2021 ◽  
Author(s):  
Kristy Tian ◽  
Haur Yueh Lee ◽  
Huee Boon Lim ◽  
Yoke Ling Chan ◽  
Ai Heong Chong ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Case Report ◽  
Literature Review ◽  
Insulin Pump ◽  
Insulin Allergy

The successful in vitro fertilization in the patient with type 1 diabetes on insulin pump therapy (case report)

2015 ◽  
Vol 21 (3) ◽  
pp. 75
Author(s):  
T. V. Nikonova ◽  
I. I. Vityazeva ◽  
E. V. Pekareva ◽  
I. I. Barmina ◽  
Yu. V. Alekseeva ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Case Report ◽  
In Vitro Fertilization ◽  
Insulin Pump ◽  
Insulin Pump Therapy ◽  
Pump Therapy ◽  
Vitro Fertilization
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