Non-Invasive Early Detection of Oral Cancers Using Fluorescence Visualization with Optical Instruments

Background: Oral cancer screening is important for early detection and early treatment, which help improve survival rates. Biopsy is the gold standard for a definitive diagnosis but is invasive and painful, while fluorescence visualization is non-invasive, convenient, and real-time, and examinations can be repeated using optical instruments. The purpose of this study was to clarify the usefulness of fluorescence visualization in oral cancer screening. Methods: A total of 502 patients, who were examined using fluorescence visualization with optical instruments in our hospitals between 2014 and 2019, were enrolled in this study. The final diagnosis was performed by pathological examination. Fluorescence visualization was analyzed using subjective and objective evaluations. Results: Subjective evaluations for detecting oral cancer offered 96.8% sensitivity and 48.4% specificity. Regarding the objective evaluations, sensitivity and specificity were 43.7% and 84.6% for mean green value, 55.2% and 67.0% for median green value, 82.0% and 44.2% for coefficient of variation of value, 59.6% and 45.3% for skewness, and 85.1% and 75.8% for value ratio. For the sub-analysis of oral cancer, all factors on objective and subjective evaluation showed no significant difference. Conclusions: Fluorescence visualization with subjective and objective evaluation is useful for oral cancer screening.

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Oral cancer screening: improving early detection

Dental Nursing ◽

10.12968/denn.2014.10.12.692 ◽

2014 ◽

Vol 10 (12) ◽

pp. 692-695

Author(s):

Pamela Prince

Keyword(s):

Cancer Screening ◽

Oral Cancer ◽

Early Detection ◽

Oral Cancer Screening

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Knowledge, Attitude and Practice of Dental Practitioners towards Screening for Oral Pre-Cancer and Cancer

Journal of Pharmaceutical Research International ◽

10.9734/jpri/2021/v33i58a34157 ◽

2021 ◽

pp. 604-611

Author(s):

J. Manju ◽

Chandrasekaran Krithika

Keyword(s):

Cancer Screening ◽

Oral Cancer ◽

Dental Students ◽

Blue Staining ◽

Cancer Awareness ◽

Attitude And Practice ◽

Dental Practitioners ◽

Significant Difference ◽

Oral Cancer Screening ◽

Knowledge Attitude And Practice

One of the global health issues is Oral cancer, which has an increased death rate. Awareness of oral cancer screening is important for oral health care professionals for early detection and improving the patients' survival rate. Attitude towards oral cancer awareness and knowledge of oral cancer screening are the key factors that impact oral cancer awareness success. Materials and Methods: To assess the knowledge, attitude, and practice of dental practitioners and dental students towards screening for oral pre-cancer and cancer. This study included dental practitioners working in various academic institutions and private practitioners in Chennai. Participants were asked to fill in age, gender, designation, and experience. A structured questionnaire consisting of 10 questions, each having four options, was administered to the participants. The data collected was 100 responses analyzed by statistical package for the social science (spss inc., version 16 for, Chicago, IL, USA). Simple descriptive statistics were used to describe the distribution of data collected. T-test and ANOVA were employed to assess the statistically significant difference in the KAP scores between different groups. Results: The response rate for the present study was 100%. 37% of general dental practitioners reported that they routinely do a thorough oral examination for all the patients,52% agree that they are adequately trained to examine patients for oral pre-cancer and cancer screening,8% of them reported that they never do toluidine blue staining for patients with oral lesion. Majority(57) of them agree that they would recommend biopsy for suspected cases of oral cancer. Only 9% of the participants were aware of the time required for intraoral screening examination. 31% of them were aware of the risk of malignant transformation in a white lesion. 73% of the participants were aware of the occurrence of oral cancer in non - tobacco users was rare. 53% of agree that thorough intraoral examination for oral cancer will reduce oral cancer mortality and morbidity.

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