scholarly journals Accuracy and Safety of Ultrasound-Guided Core Needle Biopsy of Soft Tissue Tumors in an Outpatient Setting: A Sarcoma Center Analysis of 392 Consecutive Patients

Cancers ◽  
2021 ◽  
Vol 13 (22) ◽  
pp. 5659
Author(s):  
Helene Weigl ◽  
Peter Hohenberger ◽  
Alexander Marx ◽  
Nikolaos Vassos ◽  
Jens Jakob ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Diagnostic Accuracy ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Outpatient Service ◽  
Outpatient Setting ◽  
Safe Procedure ◽  
Ultrasound Guided ◽  
Core Needle ◽  
Tertiary Referral Center

Background: The aim of this study was to investigate diagnostic accuracy, safety and histologic results of ultrasound guided core needle biopsy (CNB) in patients with soft tissue lesions (STL) at a tertiary referral center. Methods: A retrospective analysis of all consecutive patients undergoing ultrasound guided CNB for STL at our sarcoma outpatient service between January 2015 and August 2020 was performed. Results: A total of 392 patients were identified. Main histologic entities were sarcomas, lipomas and desmoid tumors. Biopsy was performed in an outpatient setting in 87.6% of the cases. Conclusive biopsies were obtained in 88.5% of the cases. In patients who underwent surgical resection after CNB, the concordance of dignity, tumor entity and histopathological grading between biopsy and resection specimen were 97.2%, 92.7% and 92.5% respectively. The risk of inconclusive CNB was highest in intraabdominal or retroperitoneal tumors (19.5%) and lowest in lesions at the lower extremity (4.4%). Major complications after CNB occurred in three cases (0.8%). No case of biopsy tract seeding was observed during the study period. Conclusions: Ultrasound guided CNB for STL at first presentation in a dedicated surgical outpatient setting is a safe procedure and yields a high diagnostic accuracy.

scholarly journals Value and Diagnostic Accuracy of Ultrasound‐Guided Full Core Needle Biopsy in the Diagnosis of Lymphadenopathy: A Retrospective Evaluation of 793 Cases

2019 ◽  
Vol 39 (3) ◽  
pp. 559-567
Author(s):  
Alexandra Wilczynski ◽  
Christian Görg ◽  
Nina Timmesfeld ◽  
Annette Ramaswamy ◽  
Andreas Neubauer ◽  
...  
Keyword(s):  
Diagnostic Accuracy ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Retrospective Evaluation ◽  
Ultrasound Guided ◽  
Core Needle ◽  
Full Core

scholarly journals Diagnostic accuracy of ultrasound-guided core needle biopsy versus incisional biopsy in soft tissue sarcoma: an institutional experience

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Miroslava Cernakova ◽  
Gerhard M. Hobusch ◽  
Gabriele Amann ◽  
Philipp T. Funovics ◽  
Reinhard Windhager ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Correct Identification ◽  
Incisional Biopsy ◽  
Ultrasound Guided ◽  
Histologic Subtype ◽  
Core Needle ◽  
Biopsy Technique

AbstractCore needle biopsy (CNB) is gaining in importance due to its advantages in the matter of patient morbidity, time and cost. Nevertheless, controversies still exist regarding the biopsy technique of choice for the accurate diagnosis of soft tissue sarcoma (STS). This retrospective cohort study compared the diagnostic performance between ultrasound-guided CNB and incisional biopsy (IB), both performed by orthopedic surgeons. The aims of the study were to answer the following questions: (1) Is ultrasound-guided CNB a highly reliable modality for diagnosing STSs? (2) Is CNB equally useful to IB for identifying histologic subtype? (3) Had patients who underwent CNB a reduced risk of complications? One-hundred and fifty-three patients who underwent resection of soft tissue sarcoma were classified into two groups according to biopsy technique prior to surgery; CNB group (n = 95) and IB group (n = 58). The final surgical specimens were in 40 patients liposarcoma (myxoid, pleomorphic and dedifferentiated), 39 undifferentiated pleomorphic sarcoma (UPS), 33 myxofibrosarcoma, 10 synovial sarcoma, 10 leiomyosarcoma and in the remaining 21 patients different soft tissue sarcoma entities. Sarcoma location of 71 patients was in the thigh, 19 in the lower leg, 22 in the upper arm and shoulder area; 10 in the knee and gluteal region, 9 in the thoracic region, the residual 12 in other body areas. Malignancy was correctly diagnosed in 87% (83 of 95) for the CNB group and 93% (54/58) for the IB group. Correct identification rate of histologic subtype was 80% (76 of 95) in the CNB group and 83% (48 of 58) in the IB group. There were no significant differences in the correct diagnosis rates of malignancy and subtype between the two techniques. No complications were seen in the CNB group, whereas 2 patients in whom IB was performed developed pulmonary embolism and 1 patient surgical site infection. Ultrasound-guided CNB is highly accurate and not inferior to IB in diagnosing the dignity of lesions and histologic subtype in patients with suspected STSs.

scholarly journals Diagnostic Accuracy and Post-Procedural Complications Associated with Ultrasound-Guided Core Needle Biopsy in the Preoperative Evaluation of Parotid Tumors

2021 ◽  
Author(s):  
Monika Jering ◽  
Marcel Mayer ◽  
Rubens Thölken ◽  
Stefan Schiele ◽  
Andrea Maccagno ◽  
...  
Keyword(s):  
Parotid Gland ◽  
Diagnostic Accuracy ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Histopathological Diagnosis ◽  
Tumor Type ◽  
Ultrasound Guided ◽  
Core Needle ◽  
Parotid Neoplasm ◽  
Procedural Complications

AbstractCorrect diagnosis of a parotid neoplasm based on histology preoperatively is of utmost importance in order to guide patient management. The aim of this study was to evaluate the diagnostic accuracy of an ultrasound-guided core needle biopsy of a parotid lesion and to describe associated post-procedural complications. A retrospective study was conducted between January 2015 and March 2021 of all patients who were referred to a tertiary care center for evaluation of a parotid lesion and who underwent core needle biopsy due to high-risk features or when malignancy was suspected on clinical examination or ultrasonography. Patient characteristics, histological findings, and post-procedural complications were recorded and evaluated. Among 890 patients referred for evaluation of a parotid lesion, in 138 patients a core needle biopsy was undertaken. On the basis of core needle biopsy findings, 11 lymphomas and 82 non-lymphoma malignancies were diagnosed in the parotid gland. The sensitivity of the core needle biopsy predicting the accurate tumor type was 97.56% (95% CI 91.47–99.70%) and the specificity 94.64% (95% CI 85.13–98.88%). The accuracy for the correct histopathological diagnosis was 93.48% (95% CI 87.98–96.97%). Post-procedural minor complications occurred in 19 patients (13.8%). In conclusion, a core needle biopsy can identify malignancy in the parotid gland with high sensitivity and specificity in a safe manner and therefore guide surgical treatment.

Percutaneous Ultrasound-Guided Core Needle Biopsy: Comparison of 16-Gauge versus 14-Gauge Needle and the Effect of Coaxial Guidance in 1065 Breast Biopsies – A Prospective Randomized Clinical Noninferiority Trial

2019 ◽  
Vol 41 (05) ◽  
pp. 534-543
Author(s):  
Ines Gruber ◽  
Ernst Oberlechner ◽  
Kerstin Heck ◽  
Uta Hoopmann ◽  
Bettina Böer ◽  
...  
Keyword(s):  
Diagnostic Accuracy ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Histological Evaluation ◽  
Ultrasound Guided ◽  
Needle Size ◽  
Core Needle ◽  
Diagnostic Quality ◽  
Noninferiority Trial

Abstract Purpose Ultrasound-guided core needle biopsy (CNB) is considered the standard assessment to diagnose sonographically visible suspicious breast mass lesions. Based on nonrandomized trials, the current German guidelines recommend at least three cylinders with ≤ 14-gauge needle biopsy. However, no recommendation is made as to how many specimens are needed with a smaller needle size, such as 16-gauge, or if biopsy with coaxial guidance improves diagnostic accuracy and quality. Therefore, in a prospective monocentric unblinded randomized controlled clinical noninferiority trial, the diagnostic accuracy of 16-gauge versus 14-gauge core needle biopsy, with and without coaxial guidance, was evaluated. Materials and Methods 1065 breast biopsies were included in order to analyze the number of core samples necessary to obtain an appropriate rate of diagnostic quality adequate for histological evaluation, and to achieve high diagnostic accuracy and diagnostic yield. Histological results were verified by surgery or long-term follow-up of at least two years up to five years. Results In order to obtain an additive diagnostic accuracy of > 99 %, a minimum of two cylinders with 14-gauge biopsy were required. The diagnostic accuracy and the diagnostic quality of 14-gauge biopsy were not affected by the coaxial technique. When performing a 16-gauge biopsy, five cylinders were required to achieve an additive diagnostic accuracy of > 99 %. Without coaxial guidance, 16-gauge CNB required at least three samples, whereas five needle passes with coaxial-guided 16-gauge biopsy were needed. Conclusion The diagnostic accuracy and quality of ultrasound-guided 16-gauge core needle biopsy were inferior to the 14-gauge needle size, regardless of the use of a coaxial technique.

Sinh thiết kim dưới hướng dẫn của siêu âm chẩn đoán u sau phúc mạc ở trẻ em: hồi cứu trên 52 bệnh nhân

2020 ◽  
Author(s):  
Thanh Huong Nguyen Thi
Keyword(s):  
Diagnostic Accuracy ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Tissue Sample ◽  
Diagnostic Value ◽  
Retroperitoneal Tumor ◽  
Large Core ◽  
Ultrasound Guided ◽  
Core Needle ◽  
Ultrasound Features

Bachground: Ultrasound-guided large core needle biopsy technique has widely been applied in the diagnosis of adult abdominopelvic, mediastinal cavity, breast and neck tumors. There are few reports on ultrasound-guided biopsy using large-core needle in pediatric solid tumor. This study was to evaluate the ultrasound features and the diagnostic value of ultrasound-guided core needle biopsy for pediatric retroperitoneal tumors. Methods: The pediatric patients with retroperitoneal tumor that determined by ultrasound, CT or MRI examination and underwent ultrasound guided core needle biopsy from October 2018 to January 2020 were reviewed at Vietnam National Children’s Hospital. A minimum of five cores in each case was obtained. 13 patients were operated and had surgical pathology results. The ultrasound features and the diagnostic accuracy of ultrasound-guided core needle biopsy were evaluated. Results: Fifty - two patients (25 males, 27 females) were enrolled into the study. Conventional ultrasound examination showed irregular hypoechoic or mixed echo masses and calcification and liquefied necrosis. The ratio of vascular encased tumors was 61.5%. The quality of tissue sample was enough to make diagnosis was 98.1% (51/52). Only one case was misdiagnosed because of inadequate tissue sample. The diagnostic accuracy of ultrasound guided core needle biopsy compared to subsequent surgical histopathology was 76.9 % (10/13). Retroperitoneal tumor pathology varied with neuroblastic tumor was 86.3% (60.8% NB, 11.8% GNB and 13.7% GN), ACC was 5.9%, germ cell tumor was 4.0% (2.0% teratoma, 2.0% yolk sac tumor) and extra renal malignant rhadoid tumor was 2.0%. No serious complication, hemorrhage or infection occurred. Conclusions: Ultrasound-guided core needle biopsy seems to be an accurate, minimally invasive, and safe diagnostic method of pediatric retroperitoneal tumor.

High diagnostic accuracy of core needle biopsy of soft tissue tumors: An institutional experience

2016 ◽  
Vol 44 (4) ◽  
pp. 291-298 ◽  
Author(s):  
Shanna M. Colletti ◽  
Ghassan A. Tranesh ◽  
Chantel R. Whetsell ◽  
Larissa N. Chambers ◽  
Aziza Nassar
Keyword(s):  
Soft Tissue ◽  
Diagnostic Accuracy ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Soft Tissue Tumors ◽  
Core Needle ◽  
High Diagnostic Accuracy ◽  
Institutional Experience
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