scholarly journals Data on the Quantification of Aspartate, GABA and Glutamine Levels in the Spinal Cord of Larval Sea Lampreys after a Complete Spinal Cord Injury

Data ◽  
2021 ◽  
Vol 6 (6) ◽  
pp. 54
Author(s):  
Blanca Fernández-López ◽  
Natividad Pereiro ◽  
Anunciación Lafuente ◽  
María Rodicio ◽  
Antón Barreiro-Iglesias
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
High Performance ◽  
Spinal Cord Transection ◽  
Cord Injury ◽  
Sea Lampreys ◽  
Complete Spinal Cord Injury

We used high-performance liquid chromatography (HPLC) methods to quantify aspartate, GABA, and glutamine levels in the spinal cord of larval sea lampreys following a complete spinal cord injury. Mature larval sea lampreys recover spontaneously from a complete spinal cord transection and the changes in neurotransmitter systems after spinal cord injury might be related to their amazing regenerative capabilities. The data presented here show the concentration of the aminoacidergic neurotransmitters GABA (and its precursor glutamine) and aspartate in the spinal cord of control (non-injured) and 2-, 4-, and 10-week post-lesion animals. Statistical analyses showed that GABA and aspartate levels significantly increase in the spinal cord four weeks after a complete spinal cord injury and that glutamine levels decrease 10 weeks after injury as compared to controls. These data might be of interest to those studying the role of neurotransmitters and neuromodulators in recovery from spinal cord injury in vertebrates.

scholarly journals Extensive neurological recovery from a complete spinal cord injury: a case report and hypothesis on the role of cortical plasticity

2013 ◽  
Vol 7 ◽  
Author(s):  
Ann S. Choe ◽  
Visar Belegu ◽  
Shoko Yoshida ◽  
Suresh Joel ◽  
Cristina L. Sadowsky ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Case Report ◽  
Cortical Plasticity ◽  
Neurological Recovery ◽  
Cord Injury ◽  
Complete Spinal Cord Injury

AB0614 Role of wnt antagonists (sclerostin and dkk-1) on bone turnover markers and bone mass, in patients with complete spinal cord injury. preliminary results

2013 ◽  
Vol 72 (Suppl 3) ◽  
pp. A977.2-A977
Author(s):  
L. Gifre ◽  
J. Vidal ◽  
S. Ruiz-Gaspà ◽  
E. Portell ◽  
A. Monegal ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Bone Mass ◽  
Bone Turnover ◽  
Bone Turnover Markers ◽  
Preliminary Results ◽  
Cord Injury ◽  
Turnover Markers ◽  
Complete Spinal Cord Injury

Role of Wnt antagonists (sclerostin and Dkk-1) on bone turnover markers and bone mass, in patients with complete spinal cord injury: preliminary results

2013 ◽  
Author(s):  
Laia Gifre ◽  
Joan Vidal ◽  
Silvia Ruiz-Gaspa ◽  
Enric Portell ◽  
Ana Monegal ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Bone Mass ◽  
Bone Turnover ◽  
Bone Turnover Markers ◽  
Preliminary Results ◽  
Cord Injury ◽  
Turnover Markers ◽  
Complete Spinal Cord Injury

scholarly journals Modeling of a Different Volume Spinal Cord Injury in Rats and Methods for Evaluation of Lost Functions Restoration (part 2)

2015 ◽  
Vol 22 (4) ◽  
pp. 60-64
Author(s):  
S. P Mironov ◽  
S. V Kolesov ◽  
G. A Stepanov ◽  
M. L Sazhnev ◽  
S. P Gubin ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Evoked Potentials ◽  
Sharp Decrease ◽  
Spinal Cord Transection ◽  
Laboratory Animals ◽  
Incomplete Spinal Cord Injury ◽  
Study Results ◽  
Cord Injury ◽  
Complete Spinal Cord Injury

The purpose of the study was to work out the methods for somatosensory evoked potentials registration under conditions of nerve paths injury in experiment. Evoked potentials were recorded in laboratory animals divided into 5 groups according to the volume of injury inflicted by the technique worked through previously. Potentials were recorded prior to intervention and on 1st, 7th, 14th, 21st, 30th and 45th postoperative day. On the 1st day sharp decrease of potential amplitudes was observed in groups with incomplete spinal cord injury. In groups with complete spinal cord injury no potentials were recorded. Slight restoration of nerve conductivity was observed only in rats with 50% spinal cord transection. Study results showed the efficacy of the technique in the assessment of spinal cord tissues conductivity and confirmed the absence of spontaneous nerve paths restoration after more than 50% of spinal cord transection.

Sign in / Sign up

Export Citation Format

Share Document