scholarly journals Diagnostic Performance of Different Simulated Low-Dose Levels in Patients with Suspected Cervical Abscess Using a Third-Generation Dual-Source CT Scanner

Diagnostics ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 1072
Author(s):  
Moritz T. Winkelmann ◽  
Saif Afat ◽  
Sven S. Walter ◽  
Eva Stock ◽  
Vincent Schwarze ◽  
...  
Keyword(s):  
Image Quality ◽  
Diagnostic Accuracy ◽  
Iterative Reconstruction ◽  
Low Dose ◽  
Sternocleidomastoid Muscle ◽  
Third Generation ◽  
Dual Source Ct ◽  
Diagnostic Confidence ◽  
Subjective Image Quality ◽  
Dual Source

The aim of this study was to investigate the effects of dose reduction on diagnostic accuracy and image quality of cervical computed tomography (CT) in patients with suspected cervical abscess. Forty-eight patients (mean age 45.5 years) received a CT for suspected cervical abscess. Low-dose CT (LDCT) datasets with 25%, 50%, and 75% of the original dose were generated with a realistic simulation. The image data were reconstructed with filtered back projection (FBP) and with advanced modeled iterative reconstruction (ADMIRE) (strengths 3 and 5). A five-point Likert scale was used to assess subjective image quality and diagnostic confidence. The signal-to-noise ratio (SNR) of the sternocleidomastoid muscle and submandibular gland and the contrast-to-noise ratio (CNR) of the sternocleidomastoid muscle and submandibular glandular fat were calculated to assess the objective image quality. Diagnostic accuracy was calculated for LDCT using the original dose as the reference standard. The prevalence of cervical abscesses was high (72.9%) in the cohort; the mean effective dose for all 48 scans was 1.8 ± 0.8 mSv. Sternocleidomastoid and submandibular SNR and sternocleidomastoid muscle fat and submandibular gland fat CNR increased with higher doses and were significantly higher for ADMIRE compared to FBP, with the best results in ADMIRE 5 (all p < 0.001). Subjective image quality was highest for ADMIRE 5 at 75% and lowest for FBP at 25% of the original dose (p < 0.001). Diagnostic confidence was highest for ADMIRE 5 at 75% and lowest for FBP at 25% (p < 0.001). Patient-based diagnostic accuracy was high for all LDCT datasets, down to 25% for ADMIRE 3 and 5 (sensitivity: 100%; specificity: 100%) and lower for FBP at 25% dose reduction (sensitivity: 88.6–94.3%; specificity: 92.3–100%). The use of a modern dual-source CT of the third generation and iterative reconstruction allows a reduction in the radiation dose to 25% (0.5 mSv) of the original dose with the same diagnostic accuracy for the assessment of neck abscesses.

scholarly journals Radiation dose and image quality of high-pitch emergency abdominal CT in obese patients using third-generation dual-source CT (DSCT)

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Robert Forbrig ◽  
Michael Ingrisch ◽  
Robert Stahl ◽  
Katharina Stella Winter ◽  
Maximilian Reiser ◽  
...  
Keyword(s):  
Image Quality ◽  
Radiation Dose ◽  
Third Generation ◽  
Obese Patients ◽  
Dual Source Ct ◽  
High Pitch ◽  
Subjective Image Quality ◽  
Dual Source ◽  
Group A

Abstract In this third-generation dual-source CT (DSCT) study, we retrospectively investigated radiation dose and image quality of portal-venous high-pitch emergency CT in 60 patients (28 female, mean age 56 years) with a body mass index (BMI) ≥ 30 kg/m2. Patients were dichotomized in groups A (median BMI 31.5 kg/m2; n = 33) and B (36.8 kg/m2; n = 27). Volumetric CT dose index (CTDIvol), size-specific dose estimate (SSDE), dose length product (DLP) and effective dose (ED) were assessed. Contrast-to-noise ratio (CNR) and dose-independent figure-of-merit (FOM) CNR were calculated. Subjective image quality was assessed using a five-point scale. Mean values of CTDIvol, SSDE as well as normalized DLP and ED were 7.6 ± 1.8 mGy, 8.0 ± 1.8 mGy, 304 ± 74 mGy * cm and 5.2 ± 1.3 mSv for group A, and 12.6 ± 3.7 mGy, 11.0 ± 2.6 mGy, 521 ± 157 mGy * cm and 8.9 ± 2.7 mSv for group B (p < 0.001). CNR of the liver and spleen as well as each calculated FOM CNR were significantly higher in group A (p < 0.001). Subjective image quality was good in both groups. In conclusion, third-generation abdominal high-pitch emergency DSCT yields good image quality in obese patients. Radiation dose increases in patients with a BMI > 36.8 kg/m2.

scholarly journals Assessment of thoracic disk herniation by using virtual noncalcium dual-energy CT in comparison with standard grayscale CT

2021 ◽  
Author(s):  
Vitali Koch ◽  
Ibrahim Yel ◽  
Leon D. Grünewald ◽  
Sebastian Beckers ◽  
Iris Burck ◽  
...  
Keyword(s):  
Image Quality ◽  
Diagnostic Accuracy ◽  
Dual Energy ◽  
Spinal Nerve ◽  
Dual Energy Ct ◽  
Third Generation ◽  
Spinal Nerve Root ◽  
Disk Herniation ◽  
Diagnostic Confidence ◽  
Dual Source

Abstract Objectives To determine the diagnostic accuracy of dual-energy CT (DECT) virtual noncalcium (VNCa) reconstructions for assessing thoracic disk herniation compared to standard grayscale CT. Methods In this retrospective study, 87 patients (1131 intervertebral disks; mean age, 66 years; 47 women) who underwent third-generation dual-source DECT and 3.0-T MRI within 3 weeks between November 2016 and April 2020 were included. Five blinded radiologists analyzed standard DECT and color-coded VNCa images after a time interval of 8 weeks for the presence and degree of thoracic disk herniation and spinal nerve root impingement. Consensus reading of independently evaluated MRI series served as the reference standard, assessed by two separate experienced readers. Additionally, image ratings were carried out by using 5-point Likert scales. Results MRI revealed a total of 133 herniated thoracic disks. Color-coded VNCa images yielded higher overall sensitivity (624/665 [94%; 95% CI, 0.89–0.96] vs 485/665 [73%; 95% CI, 0.67–0.80]), specificity (4775/4990 [96%; 95% CI, 0.90–0.98] vs 4066/4990 [82%; 95% CI, 0.79–0.84]), and accuracy (5399/5655 [96%; 95% CI, 0.93–0.98] vs 4551/5655 [81%; 95% CI, 0.74–0.86]) for the assessment of thoracic disk herniation compared to standard CT (all p < .001). Interrater agreement was excellent for VNCa and fair for standard CT (ϰ = 0.82 vs 0.37; p < .001). In addition, VNCa imaging achieved higher scores regarding diagnostic confidence, image quality, and noise compared to standard CT (all p < .001). Conclusions Color-coded VNCa imaging yielded substantially higher diagnostic accuracy and confidence for assessing thoracic disk herniation compared to standard CT. Key Points • Color-coded VNCa reconstructions derived from third-generation dual-source dual-energy CT yielded significantly higher diagnostic accuracy for the assessment of thoracic disk herniation and spinal nerve root impingement compared to standard grayscale CT. • VNCa imaging provided higher diagnostic confidence and image quality at lower noise levels compared to standard grayscale CT. • Color-coded VNCa images may potentially serve as a viable imaging alternative to MRI under circumstances where MRI is unavailable or contraindicated.

Limits of the possible: diagnostic image quality in coronary angiography with third-generation dual-source CT

2017 ◽  
Vol 106 (7) ◽  
pp. 485-492 ◽  
Author(s):  
Marco M. Ochs ◽  
Fabian aus dem Siepen ◽  
Thomas Fritz ◽  
Florian Andre ◽  
Gitsios Gitsioudis ◽  
...  
Keyword(s):  
Image Quality ◽  
Coronary Angiography ◽  
Diagnostic Image Quality ◽  
Third Generation ◽  
Dual Source Ct ◽  
Diagnostic Image ◽  
Dual Source
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