scholarly journals Passive Microwave Radiometry for the Diagnosis of Coronavirus Disease 2019 Lung Complications in Kyrgyzstan

Diagnostics ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 259
Author(s):  
Batyr Osmonov ◽  
Lev Ovchinnikov ◽  
Christopher Galazis ◽  
Berik Emilov ◽  
Mustafa Karaibragimov ◽  
...  

The global spread of severe acute respiratory syndrome coronavirus 2, which causes coronavirus disease 2019 (COVID-19), could be due to limited access to diagnostic tests and equipment. Currently, most diagnoses use the reverse transcription polymerase chain reaction (RT-PCR) and chest computed tomography (CT). However, challenges exist with CT use due to infection control, lack of CT availability in low- and middle-income countries, and low RT-PCR sensitivity. Passive microwave radiometry (MWR), a cheap, non-radioactive, and portable technology, has been used for cancer and other diseases’ diagnoses. Here, we tested MWR use first time for the early diagnosis of pulmonary COVID-19 complications in a cross-sectional controlled trial in order to evaluate MWR use in hospitalized patients with COVID-19 pneumonia and healthy individuals. We measured the skin and internal temperature using 30 points identified on the body, for both lungs. Pneumonia and lung damage were diagnosed by both CT scan and doctors’ diagnoses (pneumonia+/pneumonia−). COVID-19 was determined by RT-PCR (covid+/covid−). The best MWR results were obtained for the pneumonia−/covid− and pneumonia+/covid+ groups. The study suggests that MWR could be used for diagnosing pneumonia in COVID-19 patients. Since MWR is inexpensive, its use will ease the financial burden for both patients and countries. Clinical Trial Number: NCT04568525.

2020 ◽  
Author(s):  
Batyr Osmonov ◽  
Lev Ovchinnikov ◽  
Christopher Galazis ◽  
Berik Emilov ◽  
Mustafa Karaibragimov ◽  
...  

AbstractIt becomes clear that the COVID-19 virus is spreading globally due to limited access to diagnostics tests and equipment. Now, most of the diagnostics has been focused on RT-PCR, chest CT manifestations of COVID-19. However, there are problems with CT due to infection control, lack of CT availability in LMIC (Low Middle Income Countries) and sensitivity of RT-PCR. Passive microwave radiometry (MWR) is a cheap, non-radioactive and portable technology. It has already been used for diagnostics of cancer, and other diseases. We have tested if MWR could be used for early diagnostics of pulmonary COVID-19 complications. This was a randomized controlled trial to evaluate MWR in patients with COVID-19 pneumonia in hospitals, and in healthy individuals. We have measured skin and internal temperature at 30 points on both lungs. Pneumonia and lung damage were diagnosed by CT scan and doctor diagnosis (pn+/pn-). COVID-19 was determined by RT-PCR tests (covid+/covid-). The best MWR results were obtained between pn-/covid- and pn+/covid+ groups with sensitivity 92% and specificity 75%. The study suggests that the MWR is a safe method for diagnostics of pneumonia in COVID-19 patients. Since MWR is an inexpensive, it will ease the financial burden for both patients and the countries.Clinical Trial NumberNCT04568525Study designRandomized controlled clinical trials


1984 ◽  
Vol 15 (1) ◽  
pp. 37-46 ◽  
Author(s):  
Teng Xuyan ◽  
Shi Changqing ◽  
Peng Hongxian ◽  
Xiao Jinkai ◽  
Lai Zhaosheng ◽  
...  

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