Correction of Myopic Astigmatism with Topography-Guided Laser In Situ Keratomileusis (TOPOLINK)

We aim to assess the feasibility of topography-guided laser in situ keratomileusis (TOPOLINK) for correcting pre-existing and surgical-induced astigmatism. A retrospective, single center cohort study was conducted. Patients with pre-existing irregular myopic astigmatism were recruited into the primary group and those with irregular myopic astigmatism following laser in situ keratomileusis (LASIK) were recruited into the enhancement group. The changes in uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), maximum astigmatism, spherical equivalent (SE) and patient satisfaction were recorded. The Chi-square test, Mann–Whitney U test and Generalized Linear Mixed Model were utilized for the analysis in the current study. A total of 18 eyes were studied in the primary group and 14 eyes were examined in the enhancement group. One year postoperatively, the UCVA, BCVA, maximum astigmatism and SE improved significantly in both the primary and the enhancement groups (all p < 0.05). The UCVA (p = 0.046) and SE (p = 0.003) were worse in the primary group preoperatively but became similar in both groups postoperatively, while the BCVA and maximum astigmatism remained identical between groups throughout the study period (all p < 0.05). In addition, the rate of high and moderate satisfaction reached 90.0% in the primary and the enhancement groups, without significant differences (p = 0.871). In conclusion, the TOPOLINK showed high predictability and will contribute to similar outcomes between primary and postoperative irregular myopic astigmatism concerning visual acuity, refractive status and subject satisfaction.

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Correction of Myopia and Myopic Astigmatism by Femtosecond Laser in Situ Keratomileusis

Czech and Slovak Ophthalmology ◽

10.31348/2019/2/2 ◽

2019 ◽

Vol 75 (2) ◽

pp. 65-71

Author(s):

Tereza Řeháková ◽

Věra Veliká ◽

Naďa Jirásková

Keyword(s):

Visual Acuity ◽

Femtosecond Laser ◽

High Myopia ◽

Laser In Situ Keratomileusis ◽

Patient’S Satisfaction ◽

The Mean ◽

One Year ◽

Myopic Astigmatism

Aim: We analysed one-year refractive results and the incidence of complications in patients with correction of low-to-high myopia or myopic astigmatism by femtosecond laser in situ keratomileusis (FS-LASIK) using femtosecond laser LenSx® (Alcon, Fort Worth, Texas, USA) a excimer laser Excimer Amaris 500 (Schwind eye-tech-solutions GmbH and Co KG, Kleinostheim, Germany). Methods: To the retrospective study were included 171 eyes of 87 patients (38 men, 49 women) who underwent correction of myopia and myopic astigmatism by FS-LASIK in the outpatient Department of Ophthalmology, University Hospital in Hradec Králové between 2013-2017. We assessed uncorrected visual acuity (UCVA) and best corrected visual acuity (BCVA), subjective refraction, central corneal thickness (CCT) in the thinnest point, patient’s satisfaction and the incidence of complications in the one-year follow-up period. Results: At the time of laser procedure the mean patient‘s age was 29,26 ± 6,47 years (range 18 to 46 years). In 21 eyes was corrected myopia (range -6,5 to -2,5 D sph) and in 150 eyes myopic astigmatism (range -8,75 to -0,25 D sph and -3,0 to -0,25 D cyl). The mean preoperative UCVA 0,06 ± 0,08 (range 0,02 to 0,8) got better to 1,12 ± 0,17 (range 0,8 to 1,5) at the end of follow-up period. There wasn’t statistically significant change in BCVA between preoperative and postoperative values. Preoperative mean value of subjective refraction was -4,14 ± 1,43 D sph (range -8,5 to -1 D sph) and -0,57 ± 0,58 D cyl (range -3 to 0 D cyl) and after 12 months -0,02 ± 0,16 D sph (range -0,1 to 0,75 D sph) and -0,01 ± 0,1 D cyl (range -0,5 to 0,5 D cyl). The initial mean CCT was 554,76 ± 30,07 μm (range 485 to 660 μm), after 6 months 494,06 ± 34,99 μm (range 421 to 594 μm) and after 12 months 492,92 ± 34,55 μm (range 411 to 592 μm). We observed peroperative complications in 3 eyes. The suction loss of femtosecond laser occurred during flap creation due to sudden eye movement. Postoperatively in one case we enrolled flap pucker first postoperative day. In other case flap dislocation occurred after abdonimal surgery under general anesthesia which was performed 3 months after refractive procedure and we had to indicate flap reposition. The mean grade of patient’s satisfaction was at the end of follow-up period 1,04. The most often complaints were the sensation of dry eye (10 patients) and blurry vision during computer working, inadequate lighting and fatique (6 pacients). Conclusions: According to our experience correction of low-to-high myopia or myopic astigmatism by using FS-LASIK is an effective, relatively safe and predictable method. The basic assumption of good postoperative results and patient’s satisfaction is thorough and comprehensive preoperative examination with respect to indication criteria.

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Outcomes of Wavefront-Optimized Laser-Assisted In-Situ Keratomileusis and Photorefractive Keratectomy for correction of Myopia and Myopic Astigmatism over One Year Follow-Up

The Open Ophthalmology Journal ◽

10.2174/1874364101812010256 ◽

2018 ◽

Vol 12 (1) ◽

pp. 256-263 ◽

Cited By ~ 1

Author(s):

Mohammad M. Shehadeh ◽

Mohammad T. Akkawi ◽

Ammar A. Aghbar ◽

Muna T. Musmar ◽

Malak N Khabbas ◽

...

Keyword(s):

Visual Acuity ◽

Excimer Laser ◽

Photorefractive Keratectomy ◽

Distance Visual Acuity ◽

Visual Outcomes ◽

Corrected Distance Visual Acuity ◽

One Year ◽

Myopic Astigmatism

Background: Laser corneal refractive surgery suits, technology and nomograms are improving with time. This may improve the refractive and visual outcomes of the patients. Objectives: To evaluate the safety, efficacy, stability, and predictability of wavefront-optimized photorefractive keratectomy and Laser-assisted in-situ keratomileusis in patients with myopia and myopic astigmatism over 1-year using WaveLight® EX500 Excimer Laser machine. Methods: In this prospective cohort study, refractive and visual outcomes in 596 eyes (365 patients), either having myopia or myopic astigmatism were assessed. Patients were divided into Two groups: 1) Patients who underwent PRK (53 eyes have myopia and 217 eyes have myopic astigmatism), 2) Patients who underwent LASIK (53 eyes have myopia and 273 eyes have myopic astigmatism). Results: At 12 months postoperatively 94.3% of the myopic patients reached their preoperative best corrected distance visual acuity at the final one year follow up visit post PRK and LASIK. In patients with myopic astigmatism who underwent LASIK and PRK, 95.2%, and 96.3% of the patients reached their preoperative best corrected distance visual acuity at the final one year follow up visit post LASIK and PRK, respectively. The efficacy and safety indices were 1.00 or more for all groups with no eye lost any line of best corrected distance visual acuity. Conclusion: Our study results confirm the excellent efficacy, safety, good predictability and stability of myopia / myopic astigmatism correction by either wavefront- optimized LASIK or PRK over 1-year follow-up without significant differences between them using the WaveLight® EX500 excimer laser system.

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Comparison of outcomes after topography-modified refraction versus wavefront-optimized versus manifest topography-guided LASIK

BMC Ophthalmology ◽

10.1186/s12886-020-01459-0 ◽

2020 ◽

Vol 20 (1) ◽

Cited By ~ 1

Author(s):

Jaeryung Kim ◽

Sung-Ho Choi ◽

Dong Hui Lim ◽

Gil-Joong Yoon ◽

Tae-Young Chung

Keyword(s):

Visual Acuity ◽

Vector Analysis ◽

Laser In Situ Keratomileusis ◽

Distance Visual Acuity ◽

Postoperative Astigmatism ◽

Uncorrected Distance Visual Acuity ◽

Manifest Refraction ◽

Corrected Distance Visual Acuity ◽

Myopic Astigmatism

Abstract Background To compare the outcomes of myopia and myopic astigmatism corrected with topography-modified refraction laser in situ keratomileusis (TMR-LASIK), wavefront-optimized (WFO) LASIK, and topography-guided (TG) LASIK with a correction target based on the manifest refraction (manifest TG-LASIK). Methods This observational, retrospective cohort study included patients who underwent LASIK using the WaveLight® EX500 excimer laser to correct myopia and myopic astigmatism between August 2016 and July 2017. Patients who underwent TMR-LASIK (85 patients), WFO-LASIK (70 patients), or manifest TG-LASIK (40 patients) were enrolled, and only one eye from each patient was analyzed. All participants underwent measurement of the uncorrected distance visual acuity (UDVA), best-corrected distance visual acuity (BCVA), manifest refraction, vector analysis of astigmatic change, corneal topography, and corneal wavefront analysis at baseline and at every posttreatment visit. Results Three months postoperatively, a UDVA of 0.0 logMAR or better and manifest refraction spherical equivalent (MRSE) within ±0.5 diopters (D) did not differ across the TMR-, WFO-, and manifest TG-LASIK groups. However, the residual cylinder in the TMR group was significantly larger than that in the WFO and manifest TG groups. The magnitude of error in the TMR group measured using astigmatism vector analysis was significantly higher than that in the WFO and manifest TG groups. Conclusions Although these three LASIK platforms achieved the predicted surgical outcomes, TMR-LASIK overcorrected astigmatism and showed a higher residual postoperative astigmatism compared with WFO- and manifest TG-LASIK.

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Outcomes of LASIK for Myopia or Myopic Astigmatism Correction with the FS200 Femtosecond Laser and EX500 Excimer Laser Platform

The Open Ophthalmology Journal ◽

10.2174/1874364101812010063 ◽

2018 ◽

Vol 12 (1) ◽

pp. 63-71 ◽

Cited By ~ 5

Author(s):

Muanploy Niparugs ◽

Napaporn Tananuvat ◽

Winai Chaidaroon ◽

Chulaluck Tangmonkongvoragul ◽

Somsanguan Ausayakhun

Keyword(s):

Visual Acuity ◽

Femtosecond Laser ◽

Excimer Laser ◽

Clinical Results ◽

Laser In Situ Keratomileusis ◽

Distance Visual Acuity ◽

Astigmatism Correction ◽

Full Correction ◽

One Year ◽

Myopic Astigmatism

Purpose: To evaluate the efficacy, predictability, stability and safety of laser in situ keratomileusis (LASIK) using the FS200 femtosecond laser and EX500 excimer laser platform. Methods: The outcomes of 254 eyes of 129 consecutive patients with myopia or myopic astigmatism who underwent full correction femtosecond laser-assisted LASIK at CMU LASIK Center were assessed. Pre-operative and post-operative parameters including manifest refraction, Uncorrected Distance Visual Acuity (UDVA), Best Corrected Distance Visual Acuity (BDVA), corneal topography and tomography were analyzed. The results between low to moderate myopia and high myopia were compared up to 12 months. Results: Mean pre-operative Spherical Equivalent (SE) was -5.15±2.41 Diopters (D) (range -0.50 to -11.50 D) and -0.13±0.28 D, -0.13±0.27 D, -0.13±0.28 D and -0.14±0.30 D at 1, 3, 6, and 12 months, post-operatively. At 12 months, the propor¬tion of eyes achieving UDVA ≥ 20/20 was 90.0% and ≥20/40 was 98.8%. The proportion of eyes achieving post-operative mean SE ±0.5 D, and ±1 D was 91.3%, and 98.5%. No eyes lost more than two lines of BDVA. The low to moderate myopic group had a statistically significant better UDVA at one (p=0.017) and three months (p=0.014) but no difference at six (p=0.061) and 12 months (p=0.091). The mean post-operative SE was better in low to moderate myopic group at every follow-up visit (p=0.001, 0.007, <0.001 and <0.001). Conclusion: One-year clinical results of LASIK with the FS200 femtosecond laser and EX500 excimer laser showed high efficacy, predictability, stability and safety.

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The Impact of Biographical Information About a Composer on Emotional Responses to Their Music

Musicae Scientiae ◽

10.1177/1029864920988883 ◽

2021 ◽

pp. 102986492098888

Author(s):

Frederic Kiernan ◽

Amanda E. Krause ◽

Jane W. Davidson

Keyword(s):

Mixed Model ◽

Linear Mixed Model ◽

Emotional Responses ◽

Predictor Variable ◽

Free Text ◽

Chi Square ◽

Biographical Information ◽

Generalised Linear Mixed Model ◽

Chi Square Test ◽

The Impact

This study investigated whether reading biographical information about the composer Jan Dismas Zelenka (1679–1745) before listening to his music would influence listeners’ self-reported emotional responses. The study involved 179 participants who completed an online listening exercise in which they read either a negative or a neutral biography of Zelenka, or no biography, before listening to two short excerpts of his music. After listening to each excerpt, participants completed a 27-item questionnaire concerning their emotional responses and were then asked to describe in their own words how the music made them feel. Two-factor analyses identified five factors underlying the emotional responses of participants for each musical excerpt. Generalised Linear Mixed Model analyses indicate that the biography condition affected participants’ emotional responses with regard to memories, associations, and mental images. Positive emotional contagion was also a significant predictor variable for several of the emotional factors that were identified. A thematic analysis of participants’ free-text responses supported both the BRECVEMAC model and persona theory as interpretative frameworks, albeit with caveats. Additionally, a chi-square test of contingencies revealed that participants who read the negative biography of Zelenka were more likely to make use of negative language to describe their emotional responses to the music, and that participants who read no biography were more likely to use neutral language. The findings suggest that contextual biographical information about composers (e.g., in programme notes) can have an impact on the emotional experiences of listeners.

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Three-year outcomes of small incision lenticule extraction (SMILE) and femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) for myopia and myopic astigmatism

British Journal of Ophthalmology ◽

10.1136/bjophthalmol-2018-312140 ◽

2018 ◽

Vol 103 (4) ◽

pp. 565-568 ◽

Cited By ~ 15

Author(s):

Tian Han ◽

Ye Xu ◽

Xiao Han ◽

Li Zeng ◽

Jianmin Shang ◽

...

Keyword(s):

Visual Acuity ◽

Femtosecond Laser ◽

Laser In Situ Keratomileusis ◽

Small Incision Lenticule Extraction ◽

Small Incision ◽

Lenticule Extraction ◽

Myopic Astigmatism

AimsTo compare long-term clinical outcomes following small incision lenticule extraction (SMILE) and femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) for myopia and myopic astigmatism correction.MethodsIn this retrospective study, we enrolled a total of 101 patients (101 eyes) who underwent SMILE or FS-LASIK 3 years prior. Measured parameters included uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), manifest refraction and corneal wavefront aberrations.ResultsNo significant differences in patient characteristics were found between the two groups. At the 3-year follow-up, UDVA was better than or equal to 20/20 in 90% and 85% (p=0.540) of the eyes; the efficacy indexes were 1.05±0.19 and 1.01±0.21 in the SMILE and FS-LASIK groups, respectively (p=0.352). Safety indexes were 1.19±0.17 and 1.15±0.20 in the SMILE and FS-LASIK groups, respectively (p=0.307). Eighty per cent and 65% of eyes were within ±0.50 D of the attempted spherical equivalent correction after SMILE and FS-LASIK, respectively (p=0.164). Vector analysis revealed no significant differences in astigmatic correction between the two groups (p>0.05). Surgically induced spherical aberration was higher in the FS-LASIK group than in the SMILE group (p<0.001).ConclusionLong-term follow-up analysis suggested that both SMILE and FS-LASIK were safe and equally effective for myopic and astigmatic correction.

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Avaliação da prevalência da perda precoce de molares decíduos na dentição mista

Orthodontic Science and Practice ◽

10.24077/2020;1352-102106 ◽

2020 ◽

Vol 13 (52) ◽

pp. 102-106

Author(s):

Ana de Lourdes Sá de Lira ◽

Cassius Wander Coelho Martins ◽

Luis Paulo da Silva Dias ◽

Tito Cacau Sousa Santos

Keyword(s):

Mixed Dentition ◽

Deciduous Teeth ◽

Chi Square ◽

Space Maintainer ◽

Chi Square Test ◽

Fixed Space ◽

Deciduous Molar ◽

One Year ◽

Deciduous Molars ◽

Lower Arch

Objective: To assess primary molars early loss in mixed dentition prevalence. Method: A study was carried out in children aged 6 to 12 years. Deciduous molar loss was considered early when it occurred before Nolla stage 6 (full formed crown) of the permanent successor or one year before its physiological exfoliation. Periapical radiographs were obtained to verify the presence of the permanent successor and the level of root formation, as well as the need for placement of fixed space maintainer lingual arch or Nance button. For the study of frequency distribution of early dental loss in relation to gender and dentition, we used the Chi-square test of 5% probability level and the non-parametric Mann-Whitney test for adequate statistical analysis. Results: Of the 315 children examined, 159 (50.47%) were male and 156 (49.52%) were female. Only 25 (7.9%) presented multiple dental losses in the posterior region, 19 in the lower arch and 6 in the upper arch. In the inferior one there was predominance of first and second deciduous molars loss. There was no difference in the association between genders and the occurrence of multiple dental losses (χ² (1) = 0.03, p>0.05). Conclusion: The prevalence of deciduous teeth premature loss was of 7.9% and the most affected teeth were the first and second molars in the lower arch. Lingual arch space holders were installed in 6 children, who will remain with it until the permanent successors erupt into the oral cavity.

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