scholarly journals Predicting the Appearance of Hypotension During Hemodialysis Sessions Using Machine Learning Classifiers

Author(s):  
Juan A. Gómez-Pulido ◽  
José M. Gómez-Pulido ◽  
Diego Rodríguez-Puyol ◽  
María-Luz Polo-Luque ◽  
Miguel Vargas-Lombardo

A patient suffering from advanced chronic renal disease undergoes several dialysis sessions on different dates. Several clinical parameters are monitored during the different hours of any of these sessions. These parameters, together with the information provided by other parameters of analytical nature, can be very useful to determine the probability that a patient may suffer from hypotension during the session, which should be specially watched since it represents a proven factor of possible mortality. However, the analytical information is not always available to the healthcare personnel, or it is far in time, so the clinical parameters monitored during the session become key to the prevention of hypotension. This article presents an investigation to predict the appearance of hypotension during a dialysis session, using predictive models trained from a large dialysis database, which contains the clinical information of 98,015 sessions corresponding to 758 patients. The prediction model takes into account up to 22 clinical parameters measured five times during the session, as well as the gender and age of the patient. This model was trained by means of machine learning classifiers, providing a success in the prediction higher than 80%.

2021 ◽  
Vol 13 (8) ◽  
pp. 1433
Author(s):  
Shobitha Shetty ◽  
Prasun Kumar Gupta ◽  
Mariana Belgiu ◽  
S. K. Srivastav

Machine learning classifiers are being increasingly used nowadays for Land Use and Land Cover (LULC) mapping from remote sensing images. However, arriving at the right choice of classifier requires understanding the main factors influencing their performance. The present study investigated firstly the effect of training sampling design on the classification results obtained by Random Forest (RF) classifier and, secondly, it compared its performance with other machine learning classifiers for LULC mapping using multi-temporal satellite remote sensing data and the Google Earth Engine (GEE) platform. We evaluated the impact of three sampling methods, namely Stratified Equal Random Sampling (SRS(Eq)), Stratified Proportional Random Sampling (SRS(Prop)), and Stratified Systematic Sampling (SSS) upon the classification results obtained by the RF trained LULC model. Our results showed that the SRS(Prop) method favors major classes while achieving good overall accuracy. The SRS(Eq) method provides good class-level accuracies, even for minority classes, whereas the SSS method performs well for areas with large intra-class variability. Toward evaluating the performance of machine learning classifiers, RF outperformed Classification and Regression Trees (CART), Support Vector Machine (SVM), and Relevance Vector Machine (RVM) with a >95% confidence level. The performance of CART and SVM classifiers were found to be similar. RVM achieved good classification results with a limited number of training samples.


Author(s):  
Chunyan Ji ◽  
Thosini Bamunu Mudiyanselage ◽  
Yutong Gao ◽  
Yi Pan

AbstractThis paper reviews recent research works in infant cry signal analysis and classification tasks. A broad range of literatures are reviewed mainly from the aspects of data acquisition, cross domain signal processing techniques, and machine learning classification methods. We introduce pre-processing approaches and describe a diversity of features such as MFCC, spectrogram, and fundamental frequency, etc. Both acoustic features and prosodic features extracted from different domains can discriminate frame-based signals from one another and can be used to train machine learning classifiers. Together with traditional machine learning classifiers such as KNN, SVM, and GMM, newly developed neural network architectures such as CNN and RNN are applied in infant cry research. We present some significant experimental results on pathological cry identification, cry reason classification, and cry sound detection with some typical databases. This survey systematically studies the previous research in all relevant areas of infant cry and provides an insight on the current cutting-edge works in infant cry signal analysis and classification. We also propose future research directions in data processing, feature extraction, and neural network classification fields to better understand, interpret, and process infant cry signals.


2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Joshua E. Lewis ◽  
Melissa L. Kemp

AbstractResistance to ionizing radiation, a first-line therapy for many cancers, is a major clinical challenge. Personalized prediction of tumor radiosensitivity is not currently implemented clinically due to insufficient accuracy of existing machine learning classifiers. Despite the acknowledged role of tumor metabolism in radiation response, metabolomics data is rarely collected in large multi-omics initiatives such as The Cancer Genome Atlas (TCGA) and consequently omitted from algorithm development. In this study, we circumvent the paucity of personalized metabolomics information by characterizing 915 TCGA patient tumors with genome-scale metabolic Flux Balance Analysis models generated from transcriptomic and genomic datasets. Metabolic biomarkers differentiating radiation-sensitive and -resistant tumors are predicted and experimentally validated, enabling integration of metabolic features with other multi-omics datasets into ensemble-based machine learning classifiers for radiation response. These multi-omics classifiers show improved classification accuracy, identify clinical patient subgroups, and demonstrate the utility of personalized blood-based metabolic biomarkers for radiation sensitivity. The integration of machine learning with genome-scale metabolic modeling represents a significant methodological advancement for identifying prognostic metabolite biomarkers and predicting radiosensitivity for individual patients.


Sign in / Sign up

Export Citation Format

Share Document