scholarly journals Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study

2021 ◽  
Vol 18 (5) ◽  
pp. 2718
Author(s):  
Siret Läänelaid ◽  
Francisco B. Ortega ◽  
Theodora Kunovac Kallak ◽  
Lana Joelsson ◽  
Jonatan R. Ruiz ◽  
...  
Keyword(s):  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Infertility Treatment ◽  
Reproductive Technology ◽  
Physical Activities ◽  
Vitro Fertilization ◽  
Positive Pregnancy Test ◽  
Sedentary Activities

Background: The aim of this study was to investigate the association of physical activity (PA) with assisted reproductive technology (ART) treatment and pregnancy outcomes among couples seeking infertility treatment. Methods: This prospective cohort study was carried out among 128 infertile individuals (64 couples), entering the infertility clinic for ART procedures. Baseline PA (before entering any treatment) was assessed using accelerometry for both women and men. For every couple the infertility treatment outcomes were recorded. Results: The couples that required invasive ART procedures such as in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) spent less time in vigorous PA (−73 min/week per couple, woman + man) than those couples who became spontaneously pregnant after entering the study (p = 0.001). We observed no significant associations between the time spent in physical activities and positive pregnancy test or live birth. Conclusions: Our results do not support a positive nor negative relation between the time the couples spent in physical activities and the chances of getting pregnant or having a baby among patients seeking infertility treatment. However, couples undergoing invasive ART procedures did less vigorous PA than couples that became spontaneously pregnant, suggesting that PA may interfere with their reproductive health.

scholarly journals Factor V Leiden and prothrombin gene G20210A mutation and in vitro fertilization: prospective cohort study

2011 ◽  
Vol 26 (11) ◽  
pp. 3068-3077 ◽  
Author(s):  
G. Ricci ◽  
P. Bogatti ◽  
L. Fischer-Tamaro ◽  
E. Giolo ◽  
S. Luppi ◽  
...  
Keyword(s):  
Cohort Study ◽  
In Vitro Fertilization ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Factor V Leiden ◽  
Factor V ◽  
Vitro Fertilization ◽  
G20210a Mutation ◽  
Prothrombin Gene

scholarly journals Value of endometrial echo pattern transformation after hCG trigger in predicting IVF pregnancy outcome: a prospective cohort study

2019 ◽  
Vol 17 (1) ◽  
Author(s):  
Zhaojuan Hou ◽  
Qiong Zhang ◽  
Jing Zhao ◽  
Aizhuang Xu ◽  
Aihua He ◽  
...  
Keyword(s):  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Embryo Implantation ◽  
Implantation Rate ◽  
Endometrial Receptivity ◽  
Roc Curve Analysis ◽  
Vitro Fertilization ◽  
Hcg Trigger

Abstract Background There is much value in identifying non-invasive ways of measuring endometrial receptivity, as it has the potential to improve outcomes following in vitro fertilization (IVF). It has been suggested that endometrial echogenicity on the day of hCG administration was a good marker of endometrial receptivity. In the daily practice, we notice that patients with non-homogeneous hyperechoic endometrium on the embryo transfer day usually have lower pregnancy rates. We therefore extended the research onward transformation of echo pattern after hCG trigger to analyze the relationship between endometrial echogenicity transformation and IVF outcomes. Methods A total of 146 infertile women undergoing their first IVF cycle were recruited in the prospective cohort study from August 2017 through August 2018. A series of endometrial echo pattern monitoring was carried out in these patients after hCG trigger: hCG day, from 1 through 3 days after ovum pick-up (OPU + 1, OPU + 2, OPU + 3). Results The endometrial echogenicity value was calculated as the ratio of the hyperechogenic endometrial area over the whole endometrial area. Clinical pregnancy rate and embryo implantation rate had positive relationship with echogenicity value. The ROC curve analysis of endometrial echogenicity showed the area under curve was greatest on the second day after oocyte retrieval (OPU + 1, 2, 3 were 0.738, 0.765, 0.714 respectively) versus pregnancy. Endometrial echogenicity value on OPU + 2 had a higher predictive efficiency, and the cutoff value was 76.5%. The sensitivity was 61.3% and specificity was 82.0%. When putting the cut-off at <60%, the sensitivity was 93.8% and the specificity was 23.1%. Conclusions The endometrial echogenicity value on OPU + 2 was recommended to evaluate endometrial receptivity. It seemed appropriate for clinicians to provide a ‘freeze all’ IVF cycle and transfer in a subsequent frozen-thawed embryos cycle when echogenicity value <60% on OPU + 2. Trial registration The registration number was ChiCTR-OOC-17012214 and the registration date was August 1st, 2017.

scholarly journals Anxiety and depressive symptoms, and stress biomarkers in pregnant women after in vitro fertilization: a prospective cohort study

2018 ◽  
Vol 33 (7) ◽  
pp. 1237-1246 ◽  
Author(s):  
Ana García-Blanco ◽  
Vicente Diago ◽  
David Hervás ◽  
Farah Ghosn ◽  
Máximo Vento ◽  
...  
Keyword(s):  
Cohort Study ◽  
Depressive Symptoms ◽  
In Vitro Fertilization ◽  
Pregnant Women ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Vitro Fertilization ◽  
Stress Biomarkers
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