scholarly journals Effects of Sleep Deprivation by Olfactorily Induced Sexual Arousal Compared to Immobilization Stress and Manual Sleep Deprivation on Neuromessengers and Time Keeping Genes in the Suprachiasmatic Nuclei and Other Cerebral Entities of Syrian Hamsters—An Immunohistochemical Study

2021 ◽  
Vol 18 (17) ◽  
pp. 9169
Author(s):  
Christian Knöchel ◽  
Hagen Frickmann ◽  
Frank Nürnberger
Keyword(s):  
Sleep Deprivation ◽  
Sexual Arousal ◽  
Immobilization Stress ◽  
Steroid Receptors ◽  
Suprachiasmatic Nuclei ◽  
Syrian Hamsters ◽  
Sexual Stimulation ◽  
Sexual Steroid ◽  
Olfactory Stimuli ◽  
Light:Dark Cycle

We investigated the effects of sexual arousal induced by olfactory stimuli on the expression of neuromodulators, neurotransmitters and sexual steroid receptors in the suprachiasmatic nucleus (SCN, the circadian pacemaker of mammals) and other cerebral entities of Syrian hamsters (Mesocricetus auratus) compared to manual sleep deprivation and immobilization stress. The hamsters kept under a 12:12 hours (h) light:dark cycle were deprived of sleep by sexual stimulation, gentle manual handling or immobilization stress for 1 h at the beginning of the light phase and subsequently sacrificed at zeitgeber time 01:00, respectively; for comparison, hamsters were manually sleep deprived for 6 or 20 h or sacrificed after completing a full sleep phase. As demonstrated by immunohistochemistry, apart from various alterations after manual sleep deprivation, sexual stimulation caused down-regulation of arginine-vasopressin (AVP), vasointestinal peptide (VIP), serotonin (5-HT), substance P (SP), and met-enkephalin (ME) in the SCN. Somatostatin (SOM) was diminished in the medial periventricular nucleus (MPVN). In contrast, an increase in AVP was observed in the PVN, that of oxytocin (OXY) in the supraoptic nucleus (SON), of tyrosine-hydroxylase (TH) in the infundibular nucleus (IN), and dopamine beta-hydroxylase (DBH) in the A7 neuron population of the brain stem (A7), respectively. Testosterone in plasma was increased. The results indicate that sexual arousal extensively influences the neuropeptide systems of the SCN, suggesting an involvement of the SCN in reproductive behavior.

scholarly journals The Efficiency of Synthetic Sex Pheromones in Sexual Arousal Stimulation in Domestic Dogs

2017 ◽  
Vol 20 (3) ◽  
pp. 429-437 ◽  
Author(s):  
M. Dzięcioł ◽  
W. Niżański ◽  
T. Jezierski ◽  
A. Szumny ◽  
E.J. Godzińska ◽  
...  
Keyword(s):  
Blood Flow ◽  
Sexual Arousal ◽  
Adult Male ◽  
Sex Pheromones ◽  
Domestic Dogs ◽  
Behavioral Arousal ◽  
Sexual Stimulation ◽  
Penile Artery ◽  
Increased Blood Flow ◽  
Stimulation Of

Abstract The aim of this study was to evaluate the suitability of synthetic bitch sex pheromones (Eau’ De Estrus®, Synbiotics USA) for the stimulation of the reproductive reflexes in adult male dogs. In experiment I: anoestral bitches were applied synthetic (n=6) or natural (n=6) pheromones and their attractiveness was compared to the attractiveness of bitches in natural oestrus, In experiment II: swabs socked in natural estrual discharge or Eau D’Estrus were presented to male dogs and behavioral arousal (Exp. II a) and changes in blood flow in the penile artery reflecting erection (Exp. II b) were recorded. In experiment III the time dedicated for sniffing in experimental dogs was analyzed in relation to the type of attractant presented (natural estrual discharge or Eau D’Estrus). In all three experiments we observed the signs of sexual arousal, increased blood flow in the penile artery and increased time of sniffing only with natural pheromones. No signs of excitation or changes in penis perfusion were noted after the use of artificial pheromones. Our results did not support the suitability of Eau D’Estrus for male dog sexual stimulation.

The Effects of Partner Presence and Sexual Stimulation on the Appraisal of Vaginal Pressure and Sexual Arousal

2018 ◽  
Vol 15 (4) ◽  
pp. 539-549 ◽  
Author(s):  
Marieke Dewitte ◽  
Jan Schepers ◽  
Reinhilde Melles
Keyword(s):  
Sexual Arousal ◽  
Sexual Stimulation

Sleep homeostasis in suprachiasmatic nuclei-lesioned rats: effects of sleep deprivation and triazolam administration

1992 ◽  
Vol 589 (2) ◽  
pp. 253-261 ◽  
Author(s):  
Lorenz Trachsel ◽  
Dale M. Edgar ◽  
Wesley F. Seidel ◽  
H. Craig Heller
Keyword(s):  
Sleep Deprivation ◽  
Suprachiasmatic Nuclei ◽  
Sleep Homeostasis

scholarly journals Effect of Oxytocin on the Contractile Response in Rat Vagina

2016 ◽  
Vol 9 (1) ◽  
pp. 129-129
Author(s):  
K. Park ◽  
◽  
S. Kim ◽  
Z. Li ◽  
H. Lee ◽  
...  
Keyword(s):  
Sexual Arousal ◽  
Isometric Tension ◽  
Human Reproduction ◽  
Sprague Dawley ◽  
Vaginal Tissue ◽  
Bilateral Ovariectomy ◽  
Sexual Stimulation ◽  
Arousal Response ◽  
Induced Changes ◽  
Vaginal Smooth Muscle

Objective: Oxytocin (OT) is involved in human reproduction and serves an important role in sexual arousal. Previous studies have documented that OT levels increase during sexual stimulation and arousal with a peak during orgasm in women. The purpose of this study was to investigate the effect of OT on vaginal tissue contractility in normal and castrated rats. Design and Method: Female Sprague-Dawley rats (230–240 g, n=30) were divided into three groups: control (n=10), bilateral ovariectomy (Ovx, n=10), and bilateral ovariectomy followed by subcutaneous injections of 17β-estradiol (Ovx+Est, 50 μg/kg/day, n=10). After 4 weeks, OT receptor level and distribution was assessed in rat vaginal tissue by Western blot analyses and immunohistochemistry. In organ baths, OT-induced changes in isometric tension were also assessed in isolated strips of vaginal tissue. Results: The OT receptor was well localized in subepithelial connective tissue and vaginal smooth muscle. Exogenous application of OT (10-9 - 10-5 M.) showed a dose dependent contractile effect. In the Ovx groups, the contractile effects of OT were significantly decreased compared to control and Ovx+Est groups (p<0.05). Conclusions: These data suggest that OT receptor may have a role in female sexual function. Further studies are needed to evaluate the role of oxytocin in female sexual arousal response.

EFFECT OF SEXUAL STIMULATION AND AGE ON GENITAL BLOOD FLOW IN WOMEN WITH SEXUAL AROUSAL DISORDER

1999 ◽  
pp. 178 ◽  
Author(s):  
Tiffany Werbin ◽  
Pedram Salimpour ◽  
Laura Berman ◽  
Robert J. Krane ◽  
Irwin Goldstein ◽  
...  
Keyword(s):  
Blood Flow ◽  
Sexual Arousal ◽  
Sexual Stimulation ◽  
Arousal Disorder ◽  
Sexual Arousal Disorder

scholarly journals To rebound or not to rebound

eLife ◽  
2017 ◽  
Vol 6 ◽  
Author(s):  
Bethany A Stahl ◽  
Alex C Keene
Keyword(s):  
Sleep Deprivation ◽  
Sexual Arousal

Sexual arousal in flies counteracts the effects of sleep deprivation.

Stimulus Preference and Mental Imagery: Influencing the Way Sexual Stimuli are Viewed and the Intensity of Subjective Sexual Arousal

2018 ◽  
Author(s):  
Gabriella Boccone
Keyword(s):  
Sexual Arousal ◽  
Mental Imagery ◽  
Imagery Ability ◽  
Stimulus Preference ◽  
Sexual Stimuli ◽  
Sex Research ◽  
Sexual Stimulation ◽  
Subjective Sexual Arousal ◽  
The Relationship ◽  
Preferred Stimulus

Background: The connection between mental imagery and feelings of presence within a film has not yet been investigated in sex research in relation to observational stance (imagining oneself as either a spectator or participant while viewing a film). Several studies have shown that people who take a participant stance when viewing a sexual film are more likely to report greater subjective sexual arousal (SSA). Research on observational stance has also found that viewing a preferred stimulus is predictive of taking a participant stance. Despite this, very few studies have allowed participants to select their own stimuli. Methodology: Sexual films that were researcher-selected or participant-selected will be presented to women and men, while continuously measuring their SSA. Information will be collected about observational stance and vividness of mental imagery via questionnaires. Expected Results: 1. Greater mental imagery ability will be associated with adopting a participant stance. 2. The relationship between mental imagery ability and taking a participant stance will be stronger for participant-selected sexual stimuli than for researcher-selected sexual stimuli. 3. Taking a participant stance will be associated with greater SSA. 4. The relationship between taking a participant stance and SSA will be stronger for participant-selected sexual stimuli than for researcher-selected stimuli. Conclusions: This project is the first to examine the relationship between mental imagery and observational stance for sexual stimuli, and is among the first to allow participants to self-select stimuli. Results of this project will encourage the development of standardized procedures for providing participants with optimal sexual stimulation.

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