scholarly journals Bio-Inspired Systems in Nonsurgical Periodontal Therapy to Reduce Contaminated Aerosol during COVID-19: A Comprehensive and Bibliometric Review

2020 ◽  
Vol 9 (12) ◽  
pp. 3914
Author(s):  
Andrea Butera ◽  
Carolina Maiorani ◽  
Valentino Natoli ◽  
Ambra Bruni ◽  
Carmen Coscione ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Bacterial Load ◽  
Periodontal Therapy ◽  
Clinical Practices ◽  
Immunological Parameters ◽  
Aerosol Generation ◽  
Global Pandemic ◽  
Probing Depth ◽  
Nonsurgical Periodontal Therapy ◽  
Bibliometric Review

Background: On 30 January 2020, a public health emergency of international concern was declared as a result of the new COVID-19 disease, caused by the SARS-CoV-2 virus. This virus is transmitted by air and, therefore, clinical practices with the production of contaminant aerosols are highly at risk. The purpose of this review was to assess the effectiveness of bio-inspired systems, as adjuvants to nonsurgical periodontal therapy, in order to formulate bio-inspired protocols aimed at restoring optimal condition, reducing bacteremia and aerosols generation. Methods: A comprehensive and bibliometric review of articles published in English. Research of clinical trials (RCTs) were included with participants with chronic or aggressive periodontal disease, that have compared benefits for nonsurgical periodontal therapy (NSPT). Results: Seventy-four articles have been included. For probing depth (PPD) there was a statically significant improvement in laser, probiotic, chlorhexidine groups, such as gain in clinical attachment level (CAL). Bleeding on probing (BOP) reduction was statistically significant only for probiotic and chlorhexidine groups. There were changes in microbiological and immunological parameters. Conclusions: The use of bio-inspired systems in nonsurgical periodontal treatment may be useful in reducing risk of bacteremia and aerosol generation, improving clinical, microbiological and immunological parameters, of fundamental importance in a context of global pandemic, where the reduction of bacterial load in aerosols becomes a pivotal point of clinical practice, but other clinical trials are necessary to achieve statistical validity.

scholarly journals Adjunctive air-polishing with erythritol in nonsurgical periodontal therapy: a randomized clinical trial

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Holger F. R. Jentsch ◽  
Christian Flechsig ◽  
Benjamin Kette ◽  
Sigrun Eick
Keyword(s):  
Test Group ◽  
Nonparametric Tests ◽  
Periodontal Therapy ◽  
Periodontal Pocket ◽  
Control Group ◽  
Clinical Variables ◽  
Air Polishing ◽  
Probing Depth ◽  
Nonsurgical Periodontal Therapy ◽  
Attachment Level

Abstract Background This study was aimed to investigate if the adjunctive use of erythritol air-polishing powder applied with the nozzle-system during subgingival instrumentation (SI) has an effect on the outcome of non-surgical periodontal treatment in patients with moderate to severe periodontitis. Methods Fourty-two individuals with periodontitis received nonsurgical periodontal therapy by SI without (controls, n = 21) and with adjunctive air-polishing using nozzle + erythritol powder (test, n = 21). They were analyzed for the clinical variables BOP (primary outcome at six months), probing depth (PD), attachment level, four selected microorganisms and two biomarkers at baseline, before SI as well as three and six months after SI. Statistical analysis included nonparametric tests for intra- and intergroup comparisons. Results In both groups, the clinical variables PD, attachment level and BOP significantly improved three and six months after SI. The number of sites with PD ≥ 5 mm was significantly lower in the test group than in the control group after six months. At six months versus baseline, there were significant reductions of Tannerella forsythia and Treponema denticola counts as well as lower levels of MMP-8 in the test group. Conclusions Subgingival instrumentation with adjunctive erythritol air-polishing powder does not reduce BOP. But it may add beneficial effects like reducing the probing depth measured as number of residual periodontal pocket with PD ≥ 5 mm when compared with subgingival instrumentation only. Clinical relevance The adjunctive use of erythritol air-polishing powder applied with the nozzle-system during SI may improve the clinical outcome of SI and may reduce the need for periodontal surgery. Trial registration The study was retrospectively registered in the German register of clinical trials, DRKS00015239 on 6th August 2018, https://www.drks.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL.

scholarly journals Effect of hyperlipidemia on response to nonsurgical periodontal therapy: Statin users versus nonusers

2016 ◽  
Vol 10 (01) ◽  
pp. 069-076 ◽  
Author(s):  
Aditi Sangwan ◽  
Shikha Tewari ◽  
Harpreet Singh ◽  
Rajinder Kumar Sharma ◽  
Satish Chander Narula
Keyword(s):  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Periodontal Therapy ◽  
Periodontal Treatment ◽  
Clinical Attachment Level ◽  
Nonpharmacological Therapy ◽  
Probing Depth ◽  
Nonsurgical Periodontal Therapy ◽  
Attachment Level

ABSTRACT Objective: To evaluate the response to nonsurgical periodontal therapy among hyperlipidemic subjects and whether statin use by hyperlipidemic subjects influences the response. Materials and Methods: This study was conducted on 107 chronic periodontitis subjects (35 normolipidemic [NL] controls, 36 hyperlipidemics on nonpharmacological therapy and 36 hyperlipidemics on statins). Periodontal (plaque index, gingival index [GI], probing depth [PD], and clinical attachment level [CAL]) and biochemical (plasma triglyceride [TG], total cholesterol [TC], low-density lipoprotein cholesterol [LDL-C], and high-DL-C [HDL-C] levels) examination was done at baseline and 3 months after nonsurgical periodontal treatment. Results: Both the NL and statin groups exhibited significantly greater improvement in GI as compared to the hyperlipidemic group on nonpharmacological therapy (P = 0.004 and 0.006, respectively). Mean change in PD correlated negatively with baseline TC (r = −0.306) and LDL-C (r = −0.360) while mean change in GI positively correlated with baseline HDL-C (r = 0.219). Regression analyses revealed that mean change in PD was negatively associated with LDL-C (β = −0.358, P < 0.001) while mean change in GI was positively associated with HDL-C (β = 0.219, P = 0.023). Conclusions: While higher baseline lipid levels were somewhat detrimental to the resolution of inflammation postperiodontal treatment, the inclusion of statin therapy among hyperlipidemic subjects seemed to improve clinical response as compared to those devoid of the drug. The findings of the study are suggestive of a possible adjunctive role of statins in periodontal treatment that warrants future studies.

scholarly journals Adjunctive air-polishing with erythritol in nonsurgical periodontal therapy – a randomized clinical trial

2020 ◽  
Author(s):  
Holger F.R. Jentsch ◽  
Christian Flechsig ◽  
Benjamin Kette ◽  
Sigrun Eick
Keyword(s):  
Test Group ◽  
Nonparametric Tests ◽  
Periodontal Therapy ◽  
Periodontal Pocket ◽  
Control Group ◽  
Clinical Variables ◽  
Air Polishing ◽  
Probing Depth ◽  
Nonsurgical Periodontal Therapy ◽  
Attachment Level

Abstract Background: This study was aimed to investigate if the adjunctive use of erythritol air-polishing powder applied with the nozzle-system during subgingival instrumentation (SI) has an effect on the outcome of non-surgical periodontal treatment in patients with moderate to severe periodontitis. Methods:Forty-two individuals with periodontitis received nonsurgical periodontal therapy by SI without (controls, n=21) and with adjunctive air-polishing using nozzle + erythritol powder (test, n=21). They were analyzed for the clinical variables BOP (primary outcome at six month), probing depth (PD), attachment level (AL), four selected microorganisms and two biomarkers at baseline, before SI as well as three and six months after SI. Statistical analysis included nonparametric tests for intra- and intergroup comparisons. Results: In both groups, the clinical variables probing depth (PD), attachment level and BOP significantly improved three and six months after SI. The number of sites with PD ≥ 5mm was significantly lower in the test group than in the control group after six months. At six months vs. baseline, there were significant reductions of Tannerella forsythia and Treponema denticola counts as well as lower levels of MMP-8 in the test group. Conclusions:Subgingival instrumentation with adjunctive erythritol air-polishing powder does not reduce BOP. But it may add beneficial effects like reducing the probing depth measured as number of residual periodontal pocket with PD ≥ 5mm when compared with subgingival instrumentation only. Clinical relevanceThe adjunctive use of erythritol air-polishing powder applied with the nozzle-system during SI may improve the clinical outcome of SI and may reduce the need for periodontal surgery.

scholarly journals Use of Lasers in Nonsurgical Periodontal Therapy

2013 ◽  
Vol 2 (1) ◽  
pp. 29-32
Author(s):  
Varun Kulkarni ◽  
Juhi Uttamani ◽  
Imaad Shaikh
Keyword(s):  
Soft Tissue ◽  
Laser Therapy ◽  
Periodontal Diseases ◽  
Bacterial Load ◽  
Periodontal Therapy ◽  
Periodontal Treatment ◽  
Periodontal Pocket ◽  
Current Evidence ◽  
Area Of Interest ◽  
Nonsurgical Periodontal Therapy

ABSTRACT The use of dental lasers for treatment of periodontal diseases has been the area of interest in the recent years. Current evidence indicates that the use of lasers for the treatment of adult chronic periodontitis—either used solely or as an adjunct to traditional scaling and root planning therapy—offers minimal benefit. This article which is a peer review of various articles provides a brief explanation of the mechanism behind soft tissue lasers. The use of laser therapy in addition to traditional nonsurgical periodontal treatment in the management of periodontal diseases is reviewed. Lasers have been applied for hard and soft tissue debridement, as also for the bacterial load reduction from the periodontal pocket. Although, subgingival application of few of them during nonsurgical periodontal therapy can result in undesired outcomes, even when using manufacturer-recommended parameters. Over the past 20 years the research conducted regarding the clinical application of lasers is very limited. This article tries to fill in the void by reviewing the current and potential application of laser therapy. It has in turn proven to be a promising field in nonsurgical periodontal treatment of diseases. How to cite this article Uttamani J, Shaikh I, Kulkarni V. Use of Lasers in Nonsurgical Periodontal Therapy. Int J Experiment Dent Sci 2013;2(1):29-32.

scholarly journals Antiseptics as Adjuncts to Scaling and Root Planing in the Treatment of Periodontitis: A Systematic Literature Review

2020 ◽  
Author(s):  
Egle Ramanauskaite ◽  
Vita Machiulskiene
Keyword(s):  
Sustained Release ◽  
Meta Analysis ◽  
Periodontal Therapy ◽  
Current Evidence ◽  
Randomized Controlled Clinical Trials ◽  
Probing Depth ◽  
Central Register ◽  
Nonsurgical Periodontal Therapy ◽  
Clinical Benefits ◽  
Antiseptic Agent

Abstract Background : Periodontitis is microbially-associated, host-mediated inflammatory condition that results in loss of periodontal attachment. The goals of periodontal therapy include arresting the disease progression, establishing healthy, stable, maintainable periodontal conditions. A fundamental strategy of treating periodontitis is scaling and root planning (SRP), however its efficacy may be restricted in areas inaccessible for mechanical instrumentation. As periodontitis is infectious in nature, it might be helpful to use additional antimicrobial adjuncts, in order to eliminate or inactivate pathogenic microflora. The aim of this study is to evaluate the current evidence regarding the potential clinical benefits of using additional antiseptics for SRP in nonsurgical periodontal therapy. Methods: An electronic literature search was conducted in the MEDLINE (Ovid) and Cohrane Central Register of Controlled Trials (CENTRAL) databases for articles published between January 1, 2000 and September 22, 2019. Randomized controlled clinical trials in English that compare the effectiveness of one or more antiseptic agents as adjuncts to SRP with a follow-up of ≥ 6 months were included. A meta-analysis using the random-effects model was performed on the selected qualifying articles. Results: The search resulted in 12 articles that met the inclusion criteria. Based on the vehicle employed to deliver the antiseptic agent, studies were divided into adjunctive sustained-release antiseptics (gels, chips and varnish) and adjunctive irrigation with antiseptics. The meta-analysis demonstrated significant improvements in probing depth (PD) reduction (p = 0.001), clinical attachment level (CAL) gain (p = 0.001), and bleeding on probing (BOP) values (p = 0.001) following the adjunctive subgingival application of sustained-release antiseptics. Additional subgingival irrigation with antiseptics failed to show significant improvements in PD (p = 0.321), CAL (p = 0.7568), or BOP values (p = 0.3549) over SRP alone. Conclusions: Adjunctive subgingivally delivered antiseptics with a sustained-release delivery have significant clinical benefits compared to SRP alone.

scholarly journals Antiseptics as Adjuncts to Scaling and Root Planing in the Treatment of Periodontitis: A Systematic Literature Review

2020 ◽  
Author(s):  
Egle Ramanauskaite ◽  
Vita Machiulskiene
Keyword(s):  
Sustained Release ◽  
Meta Analysis ◽  
Periodontal Therapy ◽  
Current Evidence ◽  
Randomized Controlled Clinical Trials ◽  
Probing Depth ◽  
Central Register ◽  
Nonsurgical Periodontal Therapy ◽  
Clinical Benefits ◽  
Antiseptic Agent

Abstract Background : Periodontitis is microbially-associated, host-mediated inflammatory condition that results in loss of periodontal attachment. The goals of periodontal therapy include arresting the disease progression, establishing healthy, stable, maintainable periodontal conditions. A fundamental strategy of treating periodontitis is scaling and root planning (SRP), however its efficacy may be restricted in areas inaccessible for mechanical instrumentation. As periodontitis is infectious in nature, it might be helpful to use additional antimicrobial adjuncts, in order to eliminate or inactivate pathogenic microflora. The aim of this study is to evaluate the current evidence regarding the potential clinical benefits of using additional antiseptics for SRP in nonsurgical periodontal therapy. Methods: An electronic literature search was conducted in the MEDLINE (Ovid) and Cohrane Central Register of Controlled Trials (CENTRAL) databases for articles published between January 1, 2000 and September 22, 2019. Randomized controlled clinical trials in English that compare the effectiveness of one or more antiseptic agents as adjuncts to SRP with a follow-up of ≥ 6 months were included. A meta-analysis using the random-effects model was performed on the selected qualifying articles. Results: The search resulted in 12 articles that met the inclusion criteria. Based on the vehicle employed to deliver the antiseptic agent, studies were divided into adjunctive sustained-release antiseptics (gels, chips and varnish) and adjunctive irrigation with antiseptics. The meta-analysis demonstrated significant improvements in probing depth (PD) reduction (p = 0.001), clinical attachment level (CAL) gain (p = 0.001), and bleeding on probing (BOP) values (p = 0.001) following the adjunctive subgingival application of sustained-release antiseptics. Additional subgingival irrigation with antiseptics failed to show significant improvements in PD (p = 0.321), CAL (p = 0.7568), or BOP values (p = 0.3549) over SRP alone. Conclusions: Adjunctive subgingivally delivered antiseptics with a sustained-release delivery have significant clinical benefits compared to SRP alone.

scholarly journals Improvement of an anterior infrabone defect using combined periodontal and orthodontic therapy: A 6-year follow-up case report

2014 ◽  
Vol 08 (03) ◽  
pp. 407-411 ◽  
Author(s):  
Rafael Scaf de Molon ◽  
Yeon Jung Kim ◽  
Ary dos Santos-Pinto ◽  
Joni Augusto Cirelli
Keyword(s):  
Case Report ◽  
Periodontal Therapy ◽  
Orthodontic Movement ◽  
Novel Approach ◽  
Probing Depth ◽  
Nonsurgical Periodontal Therapy ◽  
Osseous Defect ◽  
Intraosseous Lesion ◽  
Root Movement

ABSTRACTExtensive intraosseous lesions represent a clinical challenge for the periodontist. Sites with bone defects have been shown to be at higher risk of periodontitis progression in patients who had not received periodontal therapy. Thus, the aim of this case report was to describe a novel approach for the treatment of 1-walled intraosseous defect by combining nonsurgical periodontal therapy and orthodontic movement toward the bone defect, avoiding regenerative and surgical procedures. A 47-year-old woman underwent the proposed procedures for the treatment of her left central incisor with 9 mm probing depth and 1-walled intraosseous defect in its mesial aspect. Initially, basic periodontal therapy with scaling and root planning was accomplished. Two months later, an orthodontic treatment was planned to eliminate the intraosseous lesion and to improve the interproximal papillary area. Orthodontic root movement toward the osseous defect was performed for 13 months with light forces. After 6 years postoperative it was concluded that combined basic periodontal therapy and orthodontic movement was capable of eliminating the intraosseous defect and improve the esthetics in the interproximal papillary area between the central incisors.

scholarly journals Adjunctive air-polishing with erythritol in nonsurgical periodontal therapy – a randomized clinical trial

2020 ◽  
Author(s):  
Holger F.R. Jentsch ◽  
Christian Flechsig ◽  
Benjamin Kette ◽  
Sigrun Eick
Keyword(s):  
Test Group ◽  
Nonparametric Tests ◽  
Periodontal Therapy ◽  
Periodontal Pocket ◽  
Control Group ◽  
Clinical Variables ◽  
Air Polishing ◽  
Probing Depth ◽  
Nonsurgical Periodontal Therapy ◽  
Attachment Level

Abstract Background: This study was aimed to investigate if the adjunctive use of erythritol air-polishing powder applied with the nozzle-system during subgingival instrumentation (SI) has an effect on the outcome of non-surgical periodontal treatment in patients with moderate to severe periodontitis. Methods: Fourty-two individuals with periodontitis received nonsurgical periodontal therapy by SI without (controls, n=21) and with adjunctive air-polishing using nozzle + erythritol powder (test, n=21). They were analyzed for the clinical variables BOP (primary outcome at six month), probing depth (PD), attachment level (AL), four selected microorganisms and two biomarkers at baseline, before SI as well as three and six months after SI. Statistical analysis included nonparametric tests for intra- and intergroup comparisons. Results: In both groups, the clinical variables probing depth (PD), attachment level and BOP significantly improved three and six months after SI. The number of sites with PD ≥ 5mm was significantly lower in the test group than in the control group after six months. At six months vs. baseline, there were significant reductions of Tannerella forsythia and Treponema denticola counts as well as lower levels of MMP-8 in the test group. Conclusions: Subgingival instrumentation with adjunctive erythritol air-polishing powder does not reduce BOP. But it may add beneficial effects like reducing the probing depth measured as number of residual periodontal pocket with PD ≥ 5mm when compared with subgingival instrumentation only. Clinical relevance: The adjunctive use of erythritol air-polishing powder applied with the nozzle-system during SI may improve the clinical outcome of SI and may reduce the need for periodontal surgery. Trial registration: The study was retrospectively registered in the German register of clinical trials, DRKS00015239 on 6th August 2018, https://www.drks.de/drks_web/navigate.do?navigationId =trial.HTML&TRIAL

scholarly journals Adjunctive air-polishing with erythritol in nonsurgical periodontal therapy – a randomized clinical trial

2020 ◽  
Author(s):  
Holger F.R. Jentsch ◽  
Christian Flechsig ◽  
Benjamin Kette ◽  
Sigrun Eick
Keyword(s):  
Test Group ◽  
Periodontal Therapy ◽  
Periodontal Pocket ◽  
Clinical Variable ◽  
Control Group ◽  
Clinical Variables ◽  
Air Polishing ◽  
Probing Depth ◽  
Nonsurgical Periodontal Therapy ◽  
Significant Difference

Abstract Background: This study was aimed to investigate if the adjunctive use of erythritol air-polishing powder applied with the nozzle-system during subgingival instrumentation (SI) has an effect on the outcome of non-surgical periodontal treatment in patients with moderate to severe periodontitis. Methods: Fourty-two individuals with periodontitis receiving nonsurgical periodontal therapy by SI without (controls, n=21) and with adjunctive air-polishing using nozzle + erythritol powder (test, n=21) were analyzed for clinical variables, four selected microorganisms and two biomarkers at baseline, before SI as well as three and six months after SI. Statistical analysis included nonparametric tests for intra- and intergroup comparisons. Results: In both groups, the clinical variables probing depth (PD), attachment level and BOP significantly improved three and six months after SI. The number of sites with PD ≥ 5 mm was significantly lower in the test group than in the control group after six months. At six months vs. baseline, there were significant reductions of Tannerella forsythia and Treponema denticola counts as well as lower levels of MMP-8 in the test group but not in the controls. There was no further significant difference of any clinical and non-clinical variable between both groups at three and six months after SI. Conclusions: Subgingival instrumentation with adjunctive erythritol air-polishing powder may add beneficial effects like reducing the probing depth measured as number of residual periodontal pocket with PD ≥ 5 mm when compared with subgingival instrumentation only. Clinical relevanceThe adjunctive use of erythritol air-polishing powder applied with the nozzle-system during SI may improve the clinical outcome of SI. Trial registration: The study was retrospectively registered in the German register of clinical trials, DRKS00015239 on 6th August 2018, https://www.drks.de/drks_web/navigate.do?navigationId =trial.HTML&TRIAL

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