scholarly journals Malignant Keratitis Caused by a Highly-Resistant Strain of Fusarium Tonkinense from the Fusarium Solani Complex

2021 ◽  
Vol 7 (12) ◽  
pp. 1093
Author(s):  
Jens Schrecker ◽  
Berthold Seitz ◽  
Tim Berger ◽  
Loay Daas ◽  
Wolfgang Behrens-Baumann ◽  
...  
Keyword(s):  
Virulence Factors ◽  
Fusarium Solani ◽  
Antifungal Agents ◽  
Etiologic Agent ◽  
Fusarium Spp ◽  
Opportunistic Fungi ◽  
Corneal Infection ◽  
Exact Determination ◽  
Progressive Course

Fusarium spp. are moulds ubiquitously distributed in nature and only occasionally pathogenic for humans. Species of the Fusarium solani complex are the predominant keratitis-inducing pathogens, because they are endowed with proper virulence factors. These fungi can adhere to the cornea creating a biofilm and, with the help of enzymes and cytotoxins, penetrate the cornea. Whereas an intact cornea is hardly able to be invaded by Fusarium spp. in spite of appropriate virulence factors, these opportunistic fungi may profit from predisposing conditions, for example mechanical injuries. This can lead to a progressive course of corneal infection and may finally affect the whole eye up to the need for enucleation. Here, we present and discuss the clinical, microbiological and histopathological aspects of a particular case due to Fusarium tonkinense of the Fusarium solani complex with severe consequences in a patient without any obvious predisposing factors. A broad portfolio of antifungal agents was applied, both topically and systemically as well as two penetrating keratoplasties were performed. The exact determination of the etiologic agent of the fungal infection proved likewise to be very challenging.

scholarly journals A case of mycotic keratitis caused by Fusarium solani

1995 ◽  
Vol 37 (2) ◽  
pp. 181-183 ◽  
Author(s):  
Junia Soares Hamdan ◽  
Maria Aparecida de Resende ◽  
Sarah Piancastelli Franzot ◽  
Daniel Vieira Dias ◽  
Evelin Márcia Viana ◽  
...  
Keyword(s):  
Fusarium Solani ◽  
Ocular Trauma ◽  
Systemic Disease ◽  
Mycotic Keratitis ◽  
Opportunistic Fungi ◽  
Corneal Infection ◽  
Sabouraud Dextrose Agar ◽  
Fungal Hyphae ◽  
History Of ◽  
Black Man

A 36-year-old black man, without history of systemic disease or ocular trauma developed a corneal infection in his left eye. He was treated with antibacterial antibiotic and corticosteroids for one month prior to diagnosis. Fungal hyphae and chlamydospores were found in a KOH preparation of the corneal scrapings, and positive cultures for Fusarium solani were obtained in Sabouraud dextrose agar. It is emphasized the cautious use of antibiotics and steroids in corneal diseases, and the need of considering the involvement of opportunistic fungi in the etiology of these infections.

Identificación de aislamientos clínicos de Fusarium spp mediante técnicas moleculares en Colombia.

2014 ◽  
Vol 12 (1) ◽  
pp. 143 ◽  
Author(s):  
Yesid Fabián Acevedo-Granados ◽  
Luz Elena Cano ◽  
Adelaida María Gaviria Rivera
Keyword(s):  
Fusarium Solani ◽  
Fusarium Spp

Fusariumes un género fúngico amplio y diverso de diferentes complejos deespecies, causante de una gran variedad de enfermedades en plantas, productor dediversas toxinas y representa un importante patógeno oportunista en humanos. Laidentificación de las especies de Fusarium ha sido por mucho tiempo una tareacompleja y controversial. Esto es debido principalmente a la aplicación de diferentessistemas taxonómicos y la inherente variabilidad morfológica de algunas de estasespecies. Estas características requieren de la revisión por parte de un expertomicólogo, con el fin de lograr un acertado y confiable diagnóstico, el cual es crucialen el manejo de enfermedades o infecciones y estudios de diversidad genética. EnColombia, se ha reportado un incremento anual del 317 % de casos de infeccionescausadas por Fusarium, entre 1995 y 2003, sin embargo en centros especializados anivel nacional en micología médica, no se lleva a cabo un diagnóstico a nivel deespecie. El objetivo de este estudio fue el de establecer la identidad de aislamientosclínicos de Fusarium, mediante el uso de un marcador molecular. Para lograr esteobjetivo se llevó a cabo la identificación de los 59 aislamientos mediante consulta enla base de datos Fusarium-ID con base en secuencias codificantes del factor deelongación de la traducción EF-1a. Los resultados obtenidos permitieron observar laagrupación de los 59 aislamientos en tres complejos de especies: Fusariumoxysporum(FOSC), Fusarium solani (FSSC) y Fusarium incarnanatum-equiseti(FIESC). Basado en los resultados, se observa que el uso de las secuenciascodificantes para el factor de elongación de traducción permiten una confiableclasificación de los aislamientos de origen clínico y permite ratificar la utilidad queposee este marcador molecular en los distintos complejos de Fusarium.

The Determination of Virulence Factors among Fish Originated Enterococci

2016 ◽  
Vol 27 (2) ◽  
pp. 98-103 ◽  
Author(s):  
Serap SAVAŞAN ◽  
Şükrü KIRKAN ◽  
Göksel ERBAŞ ◽  
Uğur PARIN ◽  
Alper ÇİFTCİ
Keyword(s):  
Virulence Factors

Activity of cinnamaldehyde, carvacrol and thymol combined with antifungal agents against Fusarium spp

2021 ◽  
pp. 1-7
Author(s):  
Tarcieli Pozzebon Venturini ◽  
Luana Rossato ◽  
Francieli Chassot ◽  
Maria Isabel De Azevedo ◽  
Abdullah M. S. Al-Hatmi ◽  
...  
Keyword(s):  
Antifungal Agents ◽  
Fusarium Spp

scholarly journals III. Further experiments on the vapour densities of potassium and sodium

1879 ◽  
Vol 29 (196-199) ◽  
pp. 490-493 ◽  
Keyword(s):  
Considerable Error ◽  
Exact Determination ◽  
The Way

In one former communication “On the Vapour Densities of Potas­sium and Sodium,” we pointed out the chief obstacles which lay in the way of an exact determination of these constants. Having overcome the chief manipulative difficulties in connexion with the method we described, there still remained the problem for solution as to how far the use of iron bottles in our experiments might affect the results. If the iron retained the metals or allowed their vapours to diffuse with rapidity through it, a considerable error might be produced without its being easily detected.

TO THE CALCULATION OF LENGTH OF GEOPHYSICAL OBJECTS OF HYPERBOLIC OUTLINE

2021 ◽  
pp. 85-89
Author(s):  
K. N. ANAKHAEV ◽  
◽  
B. KH. AMSHOKOV ◽  
K. K. ANAKHAEV
Keyword(s):  
Water Management ◽  
Applied Research ◽  
Free Fall ◽  
Linear Interpolation ◽  
Close Approximation ◽  
Tabular Data ◽  
Exact Determination ◽  
Complex Dependence ◽  
Incomplete Elliptic Integrals

Hyperbolic curves are used in various theoretical and practical studies, including in the field of water management and environmental construction when calculating various geophysical objects with hyperbolic outlines (surfaces of coastal slopes, sliding lines of landslide massifs, directing dams, spillway surfaces of watersheds, water free fall trajectories, etc.). The exact determination of the length of the hyperbola arc is represented by a rather complex dependence based on “unbreakable” incomplete elliptic integrals, which makes it difficult to carry out analytical calculations and involves the use of tabular data with a time-consuming cross and non-linear interpolation of them, etc. Elementary dependencies are proposed to determine the length of the hyperbola arc, which give a very close approximation (up to 1%) to exact values. The obtained calculated analytical dependencies for determining the length of the hyperbola arc are recommended for practical use in theoretical and applied research in various fi elds of science and technology.

scholarly journals On the surface-tension of liquids investigated by the method of jet vibration

1907 ◽  
Vol 80 (535) ◽  
pp. 26-27 ◽  
Keyword(s):  
Surface Tension ◽  
Cross Section ◽  
Wave Length ◽  
Standing Waves ◽  
Exact Determination ◽  
Relative Measurements

1. According to Lord Rayleigh’s theory of jet-vibrations, measurement of the length of the standing waves and the velocity and cross-section of a jet, together with the density of the liquid, affords the necessary constants for the calculation of the surface-tension. Notwithstanding the great fundamental advantages of this method, it has only been used in very few cases, and only for relative measurements of the surface-tension. The explanation hereof is to be found in the great difficulties connected with the adequate exact determination of the wave-length, and cross-section or velocity of the jet. As none of the methods in use for the measurement of these quantities could be taken as satisfactory, the main object of this investigation has been to work out really good methods for them.

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