scholarly journals Mesoporous Silica Nanoparticles in Bioimaging

Materials ◽  
2020 ◽  
Vol 13 (17) ◽  
pp. 3795
Author(s):  
Daohe Yuan ◽  
Connor M. Ellis ◽  
Jason J. Davis
Keyword(s):  
Magnetic Resonance ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Multimodal Imaging ◽  
Mesoporous Silica Nanoparticles ◽  
Physiochemical Properties ◽  
Structural Types ◽  
Optical Modes ◽  
Surface Functionalisation ◽  
Flexible Imaging

A biomedical contrast agent serves to enhance the visualisation of a specific (potentially targeted) physiological region. In recent years, mesoporous silica nanoparticles (MSNs) have developed as a flexible imaging platform of tuneable size/morphology, abundant surface chemistry, biocompatibility and otherwise useful physiochemical properties. This review discusses MSN structural types and synthetic strategies, as well as methods for surface functionalisation. Recent applications in biomedical imaging are then discussed, with a specific emphasis on magnetic resonance and optical modes together with utility in multimodal imaging.

Fluorinated Mesoporous Silica Nanoparticles for Binuclear Probes in 1H and 19F Magnetic Resonance Imaging

Langmuir ◽  
2017 ◽  
Vol 33 (40) ◽  
pp. 10531-10542 ◽  
Author(s):  
Meryem Bouchoucha ◽  
Ruud B. van Heeswijk ◽  
Yves Gossuin ◽  
Freddy Kleitz ◽  
Marc-André Fortin
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Resonance Imaging ◽  
19F Magnetic Resonance Imaging

The potential of peptide dendron functionalized and gadolinium loaded mesoporous silica nanoparticles as magnetic resonance imaging contrast agents

2016 ◽  
Vol 4 (13) ◽  
pp. 2322-2331 ◽  
Author(s):  
Chunhua Guo ◽  
Jiani Hu ◽  
Ashika Bains ◽  
Dayi Pan ◽  
Kui Luo ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Resonance Imaging ◽  
Contrast Imaging ◽  
Mri Contrast ◽  
Imaging Probes ◽  
Magnetic Resonance Imaging Contrast

Peptide dendron functionalized and gadolinium loaded mesoporous silica nanoparticles demonstrated potential as MRI contrast imaging probes owing to good biosafety and increased T1 relaxivity.

Polydopamine-coated magnetic mesoporous silica nanoparticles for multimodal cancer theranostics

2019 ◽  
Vol 7 (3) ◽  
pp. 368-372 ◽  
Author(s):  
Menghan Shi ◽  
Jiulong Zhang ◽  
Jingchao Li ◽  
Yu Fan ◽  
Jianhong Wang ◽  
...  
Keyword(s):  
Combination Therapy ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Multimodal Imaging ◽  
Mesoporous Silica Nanoparticles ◽  
Cancer Theranostics ◽  
Magnetic Mesoporous Silica

Polydopamine-coated mesoporous silica nanoparticles loaded with ultrasmall Fe3O4 nanoparticles can be prepared for multimodal imaging and combination therapy of tumors.

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