scholarly journals Evaluation of Corrosion Behavior and In Vitro of Strontium-Doped Calcium Phosphate Coating on Magnesium

Materials ◽  
2021 ◽  
Vol 14 (21) ◽  
pp. 6625
Author(s):  
Jung-Eun Park ◽  
Yong-Seok Jang ◽  
Ji-Bong Choi ◽  
Tae-Sung Bae ◽  
Il-Song Park ◽  
...  
Keyword(s):  
Corrosion Resistance ◽  
Calcium Phosphate ◽  
Pure Magnesium ◽  
Calcium Phosphate Coating ◽  
Orthopedic Implant ◽  
Phosphate Coating ◽  
Immersion Method ◽  
Magnesium Surface ◽  
Biodegradable Magnesium

This study investigated the biocompatibility of strontium-doped calcium phosphate (Sr-CaP) coatings on pure magnesium (Mg) surfaces for bone applications. Sr-CaP coated specimens were obtained by chemical immersion method on biodegradable magnesium. In this study, Sr-CaP coated magnesium was obtained by immersing pure magnesium in a solution containing Sr-CaP at 80 °C for 3 h. The corrosion resistance and biocompatibility of magnesium according to the content of Sr-CaP coated on the magnesium surface were evaluated. As a result, the corrosion resistance of Sr-CaP coated magnesium was improved compared to pure magnesium. In addition, it was confirmed that the biocompatibility of the group containing Sr was increased. Thus, the Ca-SrP coating with a reduced degradation and improved biocompatibility could be used in Mg-based orthopedic implant applications.

Corrosion resistance of glucose-induced hydrothermal calcium phosphate coating on pure magnesium

2019 ◽  
Vol 465 ◽  
pp. 1066-1077 ◽  
Author(s):  
Ling-Yu Li ◽  
Lan-Yue Cui ◽  
Bin Liu ◽  
Rong-Chang Zeng ◽  
Xiao-Bo Chen ◽  
...  
Keyword(s):  
Corrosion Resistance ◽  
Calcium Phosphate ◽  
Pure Magnesium ◽  
Calcium Phosphate Coating ◽  
Phosphate Coating

Calcium Phosphate Coating on Blast-Treated Titanium Implants by RF Magnetron Sputtering

2009 ◽  
Vol 631-632 ◽  
pp. 211-216 ◽  
Author(s):  
Kyosuke Ueda ◽  
Takayuki Narushima ◽  
Takashi Goto ◽  
T. Katsube ◽  
Hironobu Nakagawa ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Magnetron Sputtering ◽  
Bonding Strength ◽  
Rf Magnetron Sputtering ◽  
Titanium Implants ◽  
Calcium Phosphate Coating ◽  
Phosphate Coating ◽  
Coating Films

Calcium phosphate coating films were fabricated on Ti-6Al-4V plates and screw-type implants with a blast-treated surface using radiofrequency (RF) magnetron sputtering and were evaluated in vitro and in vivo. Amorphous calcium phosphate (ACP) and oxyapatite (OAp) films obtained in this study could cover the blast-treated substrate very efficiently, maintaining the surface roughness. For the in vitro evaluations of the calcium phosphate coating films, bonding strength and alkaline phosphatase (ALP) activity were examined. The bonding strength of the coating films to a blast-treated substrate exceeded 60 MPa, independent of film phases except for the film after post-heat-treatment in silica ampoule. When compared with an uncoated substrate, the increase in the ALP activity of osteoblastic SaOS-2 cells on a calcium phosphate coated substrate was confirmed by a cell culture test. The removal torque of screw-type Ti-6Al-4V implants with a blast-treated surface from the femur of Japanese white rabbit increased with the duration of implantation and it was statistically improved by coating an ACP film 2 weeks after implantation. The in vitro and in vivo studies suggested that the application of the sputtered ACP film as a coating on titanium implants was effective in improving their biocompatibility with bones.

Calcium Phosphate Coating on Titanium Using Dry Process

2010 ◽  
Vol 654-656 ◽  
pp. 2162-2167
Author(s):  
Takayuki Narushima ◽  
Kyosuke Ueda ◽  
Takashi Goto ◽  
Jun Kurihara ◽  
Hiroshi Kawamura
Keyword(s):  
Calcium Phosphate ◽  
Magnetron Sputtering ◽  
Bonding Strength ◽  
Rf Magnetron Sputtering ◽  
Calcium Phosphate Coating ◽  
Phosphate Coating ◽  
Coating Films ◽  
Removal Torque

Oxyapatite, amorphous calcium phosphate, and double-layered calcium phosphate coating films were fabricated on mirror-polished commercially pure titanium (CP Ti) and blasted Ti-6Al-4V alloy substrates by radiofrequency (RF) magnetron sputtering; the properties of these films were evaluated in vivo and in vitro. The bonding strength between the calcium phosphate films and the Ti substrates was higher than 50 MPa. This value is higher than the bonding strength reported in the case of plasma-sprayed calcium phosphate coating films fabricated on Ti substrates. The removal torque of screw-type blasted Ti-6Al-4V alloy implants in the femurs of Japanese white rabbits increased with the duration of implantation, and the removal torque values of the coated implants was observed to be higher than those of the non-coated implants. In vitro and in vivo studies indicate that coating Ti implants with calcium phosphate films using RF magnetron sputtering is effective in improving the bone compatibility of Ti implants. Finally, the factors that should be considered in fabricating biomedical coating films were discussed.

Enhancing the corrosion resistance and surface bioactivity of a calcium-phosphate coating on a biodegradable AZ60 magnesium alloy via a simple fluorine post-treatment method

RSC Advances ◽  
2015 ◽  
Vol 5 (69) ◽  
pp. 56001-56010 ◽  
Author(s):  
Yingchao Su ◽  
Yanbo Lu ◽  
Yichang Su ◽  
Jiangjiang Hu ◽  
Jianshe Lian ◽  
...  
Keyword(s):  
Corrosion Resistance ◽  
Magnesium Alloy ◽  
Calcium Phosphate ◽  
Treatment Method ◽  
Post Treatment ◽  
Calcium Phosphate Coating ◽  
Phosphate Coating

A simple fluorine post-treatment was attempted on a calcium-phosphate coating on an AZ60 alloy. Optimum fluorine post-treatment parameters were obtained. The fluorine post-treated coating showed improved corrosion protectiveness and surface bioactivity.

scholarly journals Effect of strontium doping on the biocompatibility of calcium phosphate-coated titanium substrates

2019 ◽  
Vol 17 (1) ◽  
pp. 228080001982651 ◽  
Author(s):  
Thuy-Duong Thi Nguyen ◽  
Yong-Seok Jang ◽  
Min-Ho Lee ◽  
Tae-Sung Bae
Keyword(s):  
Calcium Phosphate ◽  
Bone Regeneration ◽  
Molar Ratio ◽  
Calcium Phosphate Coating ◽  
Phosphate Coating ◽  
Biomedical Devices ◽  
Ion Release ◽  
Anodized Titanium ◽  
Strontium Doping

Background: Titanium biomedical devices coated with strontium-doped calcium phosphate ceramics can support desirable bone regeneration through anabolic and anti-catabolic effects of strontium and the compositions close to that of natural mineral tissue. Methods: Strontium was doped into the calcium phosphate coating using the cyclic pre-calcification method on the anodized titanium plate. The effects of the different concentration of strontium in treatment solution and cycle numbers of the pre-calcification treatment on the biocompatibility were investigated in terms of the changes in morphology and chemical composition of coating, ion release pattern and cytocompatibility in vitro. Results: At a high substitution ratio of strontium in the calcium phosphate coating, the size of precipitated particles was decreased and the solubility of the coating was increased. ASH55 group, which was coated by pre-calcification treatment of 20 cycles in coating solution with Sr:Ca molar ratio of 5:5, exhibited superior cellular attachment at 1 day and proliferation after 7 days of culturing in comparison with the non-doped surface and other doped surfaces. Conclusion: Sufficient strontium doping concentrations in calcium phosphate coating can enhance cell adhesion and proliferation on the titanium biomedical devices for bone regeneration.

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