scholarly journals Biomimetic Functional Surfaces towards Bactericidal Soft Contact Lenses

Micromachines ◽  
2020 ◽  
Vol 11 (9) ◽  
pp. 835
Author(s):  
Tianyu Mao ◽  
Fengzhou Fang
Keyword(s):  
Aspect Ratio ◽  
High Aspect Ratio ◽  
Contact Lenses ◽  
Influence Factors ◽  
Interaction Mechanism ◽  
Holistic Approach ◽  
Geometrical Parameters ◽  
Physical Interaction ◽  
Soft Contact ◽  
Soft Contact Lenses

The surface with high-aspect-ratio nanostructure is observed to possess the bactericidal properties, where the physical interaction between high-aspect-ratio nanostructure could exert sufficient pressure on the cell membrane eventually lead to cell lysis. Recent studies in the interaction mechanism and reverse engineering have transferred the bactericidal capability to artificial surface, but the biomimetic surfaces mimicking the topographical patterns on natural resources possess different geometrical parameters and surface properties. The review attempts to highlight the recent progress in bactericidal nanostructured surfaces to analyze the prominent influence factors and cell rupture mechanism. A holistic approach was utilized, integrating interaction mechanisms, material characterization, and fabrication techniques to establish inclusive insights into the topographical effect and mechano-bactericidal applications. The experimental work presented in the hydrogel material field provides support for the feasibility of potentially broadening applications in soft contact lenses.

scholarly journals Changes in the geometry of modern daily disposable soft contact lenses during wear

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Patryk Mlyniuk ◽  
Joanna Stachura ◽  
Alfonso Jiménez-Villar ◽  
Ireneusz Grulkowski ◽  
Bartlomiej J. Kaluzny
Keyword(s):  
Optical Coherence Tomography ◽  
Contact Lenses ◽  
Correlation Coefficients ◽  
Geometrical Parameters ◽  
Soft Contact ◽  
Corneal Surface ◽  
Swept Source ◽  
Silicone Hydrogel ◽  
Soft Contact Lenses ◽  
The Mean

AbstractThe geometry of contact lenses can be altered by wear but determining the changes that occur in soft contact lenses (SCLs) is challenging. This study aimed to investigate the shape alterations of daily disposable SCLs after wear using swept-source optical coherence tomography (SS-OCT). Forty-five eyes with myopia of − 3.00 diopters (D) were enrolled. The participants wore three types of SCLs: hydrogel lens (nesofilcon A) and silicone hydrogel lenses (delefilcon A and stenfilcon A). The SCLs were scanned 3–6 min after lens removal. We found a significant decrease in the SCL anterior curvature: 0.24 ± 0.17 mm for nesofilcon A, 0.44 ± 0.21 mm for delefilcon A, and 0.53 ± 0.29 mm for stenfilcon A. The changes in the anterior curvature of SCLs correlated moderately with the mean corneal keratometry; Pearson’s correlation coefficients for nesofilcon A and delefilcon A were 0.57 and 0.52, respectively (P < 0.001). A statistically significant change in the total diameter was observed in SCL made of stenfilcon A (0.39 mm, P < 0.001). To conclude, the central radii of curvature decreased after a wearing period for all three types of daily disposable SCLs to imitate the anterior corneal surface, however, the changes in other geometrical parameters measured with SS-OCT were lens-specific.

Peculiarities of cultivation of the monolayer of fetal fibroblasts on the soft contact lenses, with contain the collagen

2009 ◽  
Vol 21 (5) ◽  
pp. 46-50
Author(s):  
N. Pasechnikova ◽  
◽  
G. Drozhzhina ◽  
O. Ivanova ◽  
I. Nasinnik ◽  
...  
Keyword(s):  
Contact Lenses ◽  
Soft Contact ◽  
Soft Contact Lenses ◽  
Fetal Fibroblasts

Modification of therapeutic silicone-hydrogel soft contact lenses

2016 ◽  
Vol 16 (3) ◽  
pp. 117-120 ◽  
Author(s):  
T.N. Safonova ◽  
◽  
I.A. Novikov ◽  
V.I. Boev ◽  
O.V. Gladkova ◽  
...  
Keyword(s):  
Contact Lenses ◽  
Soft Contact ◽  
Silicone Hydrogel ◽  
Soft Contact Lenses

scholarly journals Myopia Control with Combination Low-Dose Atropine and Peripheral Defocus Soft Contact Lenses: A Case Series

2021 ◽  
pp. 548-554
Author(s):  
Nir Erdinest ◽  
Naomi London ◽  
Nadav Levinger ◽  
Yair Morad
Keyword(s):  
Low Dose ◽  
Contact Lenses ◽  
Case Series ◽  
Concentric Circle ◽  
Retrospective Case ◽  
Soft Contact ◽  
Myopia Progression ◽  
Soft Contact Lenses ◽  
Center Distance ◽  
Myopia Control

The goal of this retrospective case series is to demonstrate the effectivity of combination low-dose atropine therapy with peripheral defocus, double concentric circle design with a center distance soft contact lenses at controlling myopia progression over 1 year of treatment. Included in this series are 3 female children aged 8–10 years with progressing myopia averaging −4.37 ± 0.88 D at the beginning of treatment. Their average annual myopic progression during the 3 years prior to therapy was 1.12 ± 0.75 D. They had not attempted any myopia control treatments prior to this therapy. The children were treated with a combination of 0.01% atropine therapy with spherical peripheral defocus daily replacement soft lenses MiSight<sup>®</sup> 1 day (Cooper Vision, Phoenix, AZ, USA). They underwent cycloplegic refraction, and a slit-lamp evaluation every 6 months which confirmed no adverse reactions or staining was present. Each of the 3 children exhibited an average of 0.25 ± 0.25 D of myopia progression at the end of 1 year of treatment. To the best of the authors’ knowledge, this is the first published study exhibiting that combining low-dose atropine and peripheral defocus soft contact lenses is effective at controlling children’s moderate to severe myopia progression during 1 year of therapy.

Six-month evaluation of extended wear soft contact lenses among armor troops: Part I, clinical findings

1989 ◽  
Vol 16 (6) ◽  
pp. 162-168 ◽  
Author(s):  
William G. Bachman ◽  
Bruce C. Leibrecht ◽  
John K. Crosley ◽  
Dudley R. Price ◽  
Patrick M. Leas ◽  
...  
Keyword(s):  
Contact Lenses ◽  
Clinical Findings ◽  
Soft Contact ◽  
Soft Contact Lenses
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