scholarly journals The Anti-Inflammatory and Antimicrobial Potential of Selected Ethnomedicinal Plants from Sri Lanka

Molecules ◽  
2020 ◽  
Vol 25 (8) ◽  
pp. 1894
Author(s):  
Mayuri Napagoda ◽  
Jana Gerstmeier ◽  
Hannah Butschek ◽  
Sudhara De Soyza ◽  
Simona Pace ◽  
...  
Keyword(s):  
Sri Lanka ◽  
Secondary Metabolites ◽  
Medicinal Plant ◽  
Plant Species ◽  
Medicinal Plant Species ◽  
Human Neutrophils ◽  
Scavenging Activity ◽  
Garcinia Cambogia ◽  
Ms Analysis ◽  
Anti Inflammatory

Traditional folk medicine in Sri Lanka is mostly based on plants and plant-derived products, however, many of these medicinal plant species are scientifically unexplored. Here, we evaluated the anti-inflammatory and antimicrobial potency of 28 different extracts prepared from seven popular medicinal plant species employed in Sri Lanka. The extracts were subjected to cell-based and cell-free assays of 5-lipoxygenase (5-LO), microsomal prostaglandin E2 synthase (mPGES)-1, and nitric oxide (NO) scavenging activity. Moreover, antibacterial and disinfectant activities were assessed. Characterization of secondary metabolites was achieved by gas chromatography coupled to mass spectrometric (GC-MS) analysis. n-Hexane- and dichloromethane-based extracts of Garcinia cambogia efficiently suppressed 5-LO activity in human neutrophils (IC50 = 0.92 and 1.39 µg/mL), and potently inhibited isolated human 5-LO (IC50 = 0.15 and 0.16 µg/mL) and mPGES-1 (IC50 = 0.29 and 0.49 µg/mL). Lipophilic extracts of Pothos scandens displayed potent inhibition of mPGES-1 only. A methanolic extract of Ophiorrhiza mungos caused significant NO scavenging activity. The lipophilic extracts of G. cambogia exhibited prominent antibacterial and disinfectant activities, and GC-MS analysis revealed the presence of fatty acids, sesquiterpenes and other types of secondary metabolites. Together, our results suggest the prospective utilization of G. cambogia as disinfective agent with potent anti-inflammatory properties.

scholarly journals Synthetic Seed Production as a Tool for the Conservation and Domestication of Celastrus paniculatus: A Rare Medicinal Plant

2019 ◽  
pp. 1-8
Author(s):  
D. L. C. K. Fonseka ◽  
W. W. U. I. Wickramaarachchi ◽  
R. P. S. Madushani
Keyword(s):  
Sri Lanka ◽  
Medicinal Plant ◽  
Plant Species ◽  
Synthetic Seeds ◽  
Shoot Tips ◽  
Medicinal Plant Species ◽  
Synthetic Seed ◽  
Black Oil ◽  
Celastrus Paniculatus

The black-oil tree (Celastrus paniculatus Willd) is a highly valued medicinal plant species belong to the Celastraceae family, known as Jyothishmathi in Ayurveda and Duhundu in Sri Lanka and grows as a perennial vine. It is an endangered medicinal plant species recorded in the red list of endangered fauna and flora of Sri Lanka in 1999. The seed oil of Celastrus paniculatus contains sesquiterpene alkaloids namely; celapagine, celapanigine, celapanine and celastrol, used in traditional system of medicine for various disorders and because of its high pharmaceutical value, plants are over exploited in natural habitats. Owing to poor seed germination and lack of successful vegetative propagation methods, domestication and commercial planting of this important medicinal plant species to meet the demand seems impossible. Therefore, it is of high importance to develop a reliable and efficient in vitro propagation to produce black oil plants for commercial use. In this study, it was attempted to produce synthetic seeds of Celestrus paniculatus via in vitro multiple shoot proliferation. Nodal segment explants were collected from freshly emerged age of sprouts, surface sterilized and cultured in Murashige and Skoog medium supplemented with different 6-benzylaminopurine (BAP) and Thidiazuron (TDZ) concentrations for shoot induction. The highest soot proliferation rate; 25 shoot tips/explant were observed with 0.1 mg/L TDZ. Induced shoot tips were used for synthetic seed production after encapsulating with BAP and a-naphthalene acetic (NAA) enriched sodium alginate. Shoot tip encapsulated beads produced with 4% sodium alginate were firm, clear, round and uniform in size and easy to handle. The influence of growth regulators (BAP and NAA) and storage period on the germination of encapsulated shoot tips was studied to evaluate the success of encapsulated shoot tips as a propagule. The beads germinated with 2 mg/L BAP and 0.2 mg/L NAA provided 80% in vitro germination percentage. Shoot tips of synthetic seeds remained green and healthy after storage at 5°C for a period of 8 weeks. Current findings suggest that encapsulated micro shoots (synthetic seeds) could be produced successfully, as the first step in domestication and conservation of Celastrus paniculatus. Further studies required on rooting of micro shoots, acclimatization and transferring of plantlets produced from synthetic seeds to in vivo conditions for domestication and conservation purposes.

scholarly journals Phytochemical screening of some antidysenteric medicinal plants of Bangladesh

2014 ◽  
Vol 39 (2) ◽  
pp. 139-146
Author(s):  
ANM Alamgir ◽  
Kaniz Fatema
Keyword(s):  
Medicinal Plants ◽  
Secondary Metabolites ◽  
Medicinal Plant ◽  
Plant Species ◽  
Relative Effectiveness ◽  
Qualitative Assessment ◽  
Medicinal Plant Species ◽  
Phytochemical Screening ◽  
Test Plants ◽  
Better Than

In this report, 40 antidysenteric medicinal plant species representing 24 families were considered for qualitative assessment of their secondary metabolites like alkaloids, flavonoids, glycosides, sterols and tannins. Alkaloids were present in all plant species, though in different degrees and the relative effectiveness of Dragendorffs’ reagent was better than others. Distribution of flavonoids, glycosides, sterols and tannins was sporadic in different plant species except A. cepa, A. marmelos, I. coccinea, M. indica, S. dulcis and Z. officinale, where all these metabolites were present. Abundance and mode of distribution of secondary metabolites in different test plants and their organs were discussed. DOI: http://dx.doi.org/10.3329/jasbs.v39i2.17850 J. Asiat. Soc. Bangladesh, Sci. 39(2): 139-146, December 2013

Uncommon fatty acids, Iridoids and other secondary metabolites from the medicinal plant species Ixora cibdela Craib (Rubiaceae)

2019 ◽  
Vol 33 ◽  
pp. 77-80 ◽  
Author(s):  
Raveevatoo Buathong ◽  
Florian Schindler ◽  
Johann Schinnerl ◽  
Karin Valant-Vetschera ◽  
Markus Bacher ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Secondary Metabolites ◽  
Medicinal Plant ◽  
Plant Species ◽  
Medicinal Plant Species

scholarly journals Dormancy break in seeds of "quina" (Strychnos pseudoquina A. St.-Hil.)

2011 ◽  
Vol 13 (4) ◽  
pp. 507-511 ◽  
Author(s):  
J.M. Vasconcelos ◽  
M.A. Rodrigues ◽  
S.C. Vasconcelos Filho ◽  
J.F. Sales ◽  
F.G. Silva ◽  
...  
Keyword(s):  
Sulfuric Acid ◽  
Medicinal Plant ◽  
Gibberellic Acid ◽  
Plant Species ◽  
Germination Percentage ◽  
Boiling Water ◽  
Medicinal Plant Species ◽  
Distilled Water ◽  
Brazilian Cerrado ◽  
Germination Speed

"Quina" (Strychnos pseudoquina A. St. Hil) is a medicinal plant species from the Brazilian Cerrado. As its seeds show dormancy, they were subjected to the treatments pre-cooling at 5ºC during 7 days, pre-heating at 40ºC during 7 days, pre-soaking in sulfuric acid PA during 5 and 15 min, pre-soaking in boiling water during 5 and 15 min, pre-soaking in 100 and 200 ppm gibberellic acid during 48 h, pre-soaking in distilled water during 24 and 48 h, and mechanical scarification to break dormancy. Counts were daily conducted from the 2nd day after the experiment implementation until the germination stabilization at the 65th day. The germination speed index (GSI) and the germination percentage were evaluated. Germination rates above 96% were reached in seeds pre-soaked in water during 48 h and substrate moistened with water or KNO3.

Sign in / Sign up

Export Citation Format

Share Document