scholarly journals Human Biomonitoring of Selected Hazardous Compounds in Portugal: Part I—Lessons Learned on Polycyclic Aromatic Hydrocarbons, Metals, Metalloids, and Pesticides

Molecules ◽  
2021 ◽  
Vol 27 (1) ◽  
pp. 242
Author(s):  
Angelina Pena ◽  
Sofia Duarte ◽  
André M. P. T. Pereira ◽  
Liliana J. G. Silva ◽  
Célia S. M. Laranjeiro ◽  
...  

Human biomonitoring (HBM) data provide information on total exposure regardless of the route and sources of exposure. HBM studies have been applied to quantify human exposure to contaminants and environmental/occupational pollutants by determining the parent compounds, their metabolites or even their reaction products in biological matrices. HBM studies performed among the Portuguese population are disperse and limited. To overcome this knowledge gap, this review gathers, for the first time, the published Portuguese HBM information concerning polycyclic aromatic hydrocarbons (PAHs), metals, metalloids, and pesticides concentrations detected in the urine, serum, milk, hair, and nails of different groups of the Portuguese population. This integrative insight of available HBM data allows the analysis of the main determinants and patterns of exposure of the Portuguese population to these selected hazardous compounds, as well as assessment of the potential health risks. Identification of the main difficulties and challenges of HBM through analysis of the enrolled studies was also an aim. Ultimately, this study aimed to support national and European policies promoting human health and summarizes the most important outcomes and lessons learned through the HBM studies carried out in Portugal.

Molecules ◽  
2021 ◽  
Vol 27 (1) ◽  
pp. 130
Author(s):  
Angelina Pena ◽  
Sofia Duarte ◽  
André M. P. T. Pereira ◽  
Liliana J. G. Silva ◽  
Célia S. M. Laranjeiro ◽  
...  

Human biomonitoring (HBM) data provide information on total exposure regardless of the route and sources of exposure. HBM studies have been applied to quantify human exposure to contaminants and environmental/occupational pollutants by means of determining the parent compounds, their metabolites, or even their reaction products in biological matrices. HBM studies performed among the Portuguese population are dispersed and limited. Thus, to overcome this knowledge gap, this work reviews the published Portuguese HBM information concerning mycotoxins detected in the urine, serum, milk, hair, and nails of different groups of the Portuguese population. This integrative approach to the available HBM data allows us to analyze the main determinants and patterns of exposure of the Portuguese population to the selected hazardous compounds, as well as to assess the potential health risks. We also aimed to identify the main difficulties and challenges of HBM through the analysis of the enrolled studies. Ultimately, this study aims to support national and European policies in promoting human health by summarizing the most important outcomes and lessons learned through the HBM studies carried out in Portugal.


2019 ◽  
Vol 37 (4) ◽  
pp. 394-401 ◽  
Author(s):  
Weihua Gu ◽  
Jianfeng Bai ◽  
Wenyi Yuan ◽  
En Ma ◽  
Chenglong Zhang ◽  
...  

Polycyclic aromatic hydrocarbons (PAHs) are considered to be persistent organic pollutants, which pose a great threat to human health and the surrounding environment. In order to explore the influence of informal electronic waste (e-waste) dismantling activities on inhabitants who live nearby, soil samples were collected from informal e-waste dismantling areas in Xinqiao, China and analysed for 16 United States Environmental Protection Agency (USEPA) priority PAHs. Results indicated that the 16 USEPA priority PAHs were found at all seven sampling locations. Sampling location 3, which was only 10 m away from a residential area, had 1053.69 μg kg−1 of PAHs and seriously exceeded the standard value specified by the Netherlands. The total percents of 4-ring and 5-ring PAHs accounted for 61.74 and 71.70%, respectively, indicating that most of the detected PAHs belonged to high-ring PAHs. The informal e-waste dismantling activities are the major sources of soil PAHs in Xinqiao. Furthermore, the concentration of seven carcinogenic PAHs was 114.76 μg kg−1 and represented a potential health risk to humans. Thereinto, benzo[a]pyrene contributed the most, accounting for more than 50% in these locations. Our results may provide a reference about the influence of informal e-waste dismantling activities on the surrounding inhabitants and suggest that e-waste dismantling activities must be conducted in a formal enterprise which is far away from residential areas.


2016 ◽  
Vol 2016 (1) ◽  
Author(s):  
Giovanna Tranfo* ◽  
Lisa Bauleo ◽  
Carla Ancona ◽  
Francesco Forastiere ◽  
Enrico Paci ◽  
...  

2019 ◽  
Vol 8 (3) ◽  
pp. 58
Author(s):  
A. Dokubo ◽  
F. U. Igwe

Polycyclic Aromatic Hydrocarbons (PAHs) were assessed in shellfishes (whelk, oyster and periwinkle) from Kula, Rivers State, Nigeria. The PAHs determination was done using gas chromatography (GC) coupled with flame ionization detector (FID) (Hewlett Packard, Wilmington, DE, USA), powered with HP chemstation Rev. A09:01 (10206) software. Human health risk assessment models based on United States Environmental Protection Agency (USEPA) was used to characterize risks of PAHs exposure to non cancer (Hazard Index) while and excess cancer risk (ECR). From the results, Benzo [a] Anthrancene (BaA) had highest concentrations in whelk (0.689±0.003) and Periwinkle (0.930±0.001) while Naphthalene had highest concentration in oyster (2.000±0.000). The Total concentration of PAHs in µ g/kg for whelk, oyster and periwinkle were 1.797±0.013, 3.977 ±0.024 and 1.564±0.017 while the estimated daily intake (EDI) of PAHs (mg/kg/day) via consumption of shell fish ranged from 2.00x10-4 to 6.40x10-2, 7.0x10-4 to 1.86 x10-1 and 0 to 8.64x10-2 far above oral reference dose (RFD) respectively. The toxic equivalents (TEQs) values were 1.276x10-4, 1.252x10-4 and 4.034x10-4 for whelk, oyster and periwinkle respectively, were significantly (p<0.05) higher than the screening value (SV) for shellfish 1.81x10-5mg/kg. The estimated excess cancer risk (ECR) obtained for whelk was (3.0x10-4), oyster (2.00x10-4) and periwinkle (3.24x10-4). These values were far above the USEPA acceptable (1x10-4). From this study, it can be deduced that bioaccumulation of PAHs in the shellfish is a potential health hazard to consumers. Carcinogenic indices indicated that daily Intake of contaminated shellfishes exposures the local populace to cancer risks.


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