scholarly journals Handgrip Strength: Associations with Clinical Variables, Body Composition, and Bone Mineral Density in Adults with Cystic Fibrosis

Nutrients ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 4107
Author(s):  
Victoria Contreras-Bolívar ◽  
Casilda Olveira ◽  
Ignacio Ruiz-García ◽  
Nuria Porras ◽  
Maria García-Olivares ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Cystic Fibrosis ◽  
Body Composition ◽  
Bone Mineral ◽  
Muscle Function ◽  
Respiratory Function ◽  
Handgrip Strength ◽  
Fat Free Mass ◽  
Mineral Density ◽  
The Mean

Background: Loss of fat-free mass (FFM) is associated with an increase in morbidity and mortality in cystic fibrosis (CF) patients. Handgrip strength (HGS) measures muscle function and may be associated with clinical parameters with prognostic value. Our objectives were to evaluate muscle strength through HGS in CF patients and to determine if there are any associations with respiratory clinical variables, FFM, and bone mineral density (BMD). Methods: A cross-sectional study conducted in clinically stable patients. We evaluated muscle function through HGS, respiratory function—forced expiratory volume in 1 s (FEV1) (%), forced vital capacity (FVC) (%), bronchorrhea, annual exacerbations, and body composition (FFM and FFM index, FFMI: fat-free mass in kg/height in m2) and Bone Mineral Density (BMD) through densitometry (DXA). Results: The study included 53 CF patients (58.5% females, mean age 28.3 ± 8.1, body mass index (BMI) 21.7 ± 3.4). The mean values for dynamometry were 40.2 ± 8.1 kg in males and 23.1 ± 7.0 kg in women, being 20.8% below the 10th percentile. Patients with lower muscle strength showed significantly more exacerbations and lower FEV1% and FVC%, as well as lower BMI, worse BMD (g/cm2), T-score, and Z-score. A significant and positive correlation was found between the mean and maximum dynamometry values and age, FVC%, BMI, FFMI, FFM (kg), and BMD. Conclusions: For adults with CF, HGS is a practical tool for assessment of health status. Low values reflect poor nutritional status and are associated with poor respiratory function, low fat-free mass and low bone mineral density.

scholarly journals Bone mineral density and body composition in adolescents with failure to thrive

2010 ◽  
Vol 8 (2) ◽  
pp. 168-174
Author(s):  
Thiago Sacchetto de Andrade ◽  
Luiz Anderson Lopes ◽  
Marcelo de Medeiros Pinheiro ◽  
Vera Lucia Szejnfeld ◽  
José Augusto de Aguiar Carrazedo Taddei
Keyword(s):  
Bone Mineral Density ◽  
Body Composition ◽  
Bone Mass ◽  
Bone Mineral ◽  
Fat Mass ◽  
Failure To Thrive ◽  
Fat Free Mass ◽  
Z Score ◽  
Mineral Density ◽  
Total Fat

ABSTRACT Objective To evaluate bone mineral mass in adolescents with failure to thrive in relation to body composition. Methods A case control study involving 126 adolescents (15 to 19 years), in final puberty maturation being 76 eutrophic and 50 with failure to thrive (genetic or constitutional delay of growth), of matching ages, gender and pubertal maturation. The weight, height and calculated Z score for height/age and body mass index; bone mineral content, bone mineral density and adjusted bone mineral density were established for total body, lower back and femur; total fat-free mass and height-adjusted fat-free mass index, total fat mass and height-adjusted. The statistical analyses were performed using the Student's t-test (weight, height and body composition); Mann-Whitney test (bone mass) and multiple linear regression (bone mass determinants). Results weight, height and height/age Z-score were significantly higher among eutrophic subjects. Both groups did not show statistically significant differences for fat mass, percentage of fat mass, total fat mass height adjusted and fat-free mass index height sadjusted. However, total free fat maass was smaller for the failure to thrive group. Conclusions There was no statistically significant difference for bone mass measurements among adolescents with failure to thrive; however, the factors that determine bone mass formation should be better studied due to the positive correlation with free fat mass detected in these individuals.

scholarly journals Bone mineral density and body composition in adult patients with cystic fibrosis.

Thorax ◽  
1993 ◽  
Vol 48 (6) ◽  
pp. 589-593 ◽  
Author(s):  
A B Grey ◽  
R W Ames ◽  
R D Matthews ◽  
I R Reid
Keyword(s):  
Bone Mineral Density ◽  
Cystic Fibrosis ◽  
Body Composition ◽  
Bone Mineral ◽  
Adult Patients ◽  
Mineral Density

scholarly journals Comparison of Muscle Function, Bone Mineral Density and Body Composition of Early Starting and Later Starting Older Masters Athletes

2019 ◽  
Vol 10 ◽  
Author(s):  
Jessica Piasecki ◽  
Alex Ireland ◽  
Mathew Piasecki ◽  
Kevin Deere ◽  
Kimberley Hannam ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Body Composition ◽  
Bone Mineral ◽  
Muscle Function ◽  
Mineral Density ◽  
Masters Athletes

scholarly journals Recurrent pulmonary exacerbations are associated with low fat free mass and low bone mineral density in young adults with cystic fibrosis

2014 ◽  
Vol 13 (3) ◽  
pp. 328-334 ◽  
Author(s):  
Gianfranco Alicandro ◽  
Arianna Bisogno ◽  
Alberto Battezzati ◽  
Maria Luisa Bianchi ◽  
Fabiola Corti ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Cystic Fibrosis ◽  
Young Adults ◽  
Bone Mineral ◽  
Fat Free Mass ◽  
Mineral Density ◽  
Low Fat ◽  
Low Bone Mineral Density ◽  
Pulmonary Exacerbations

Associations among Geriatric Nutrition Risk Index, bone mineral density, body composition and handgrip strength in patients receiving hemodialysis

Nutrition ◽  
2019 ◽  
Vol 65 ◽  
pp. 6-12 ◽  
Author(s):  
Szu-Chia Chen ◽  
Wei-Shiuan Chung ◽  
Pei-Yu Wu ◽  
Jiun-Chi Huang ◽  
Yi-Wen Chiu ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Body Composition ◽  
Bone Mineral ◽  
Handgrip Strength ◽  
Risk Index ◽  
Mineral Density ◽  
Nutrition Risk

scholarly journals Bone Mineral Density in Cystic Fibrosis Patients with the CFTR I1234V Mutation in a Large Kindred Family Is Associated with Pancreatic Sufficiency

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Atqah Abdul Wahab ◽  
M. Hammoudeh ◽  
Mona Allangawi ◽  
Fawziya Al-Khalaf ◽  
Prem Chandra
Keyword(s):  
Bone Mineral Density ◽  
Cystic Fibrosis ◽  
Lumbar Spine ◽  
Bone Mineral ◽  
Whole Body ◽  
Mineral Density ◽  
Total Hip ◽  
Radiographic Absorptiometry ◽  
The Mean ◽  
Total Body

Objectives. To study bone mineral density (BMD) in cystic fibrosis (CF) children and adults with the CFTR I1234V mutation associated with pancreatic sufficiency.Methods. Lumbar spine, total hip, and whole-body mineral density were measured by dual-energy radiographic absorptiometry (DEXA) scan.Zscore was used for those less than 21 years andTscore was used for those 21 years or older.Results. Twenty-one CF patients were younger than 21 years and 5 CF patients were 21 years or older. Mean age was 17.29 ± 4.95 years, ranging from 10 to 33 years. The mean BMDZscores for patients younger than 21 years were −0.69 ± 0.96 (lumbar spine = L1–L4), −0.48 ± 0.92 (total hip), and −0.38 ± 0.86 (total body). The meanTscores for patients 21 years or older were 0.14 ± 0.7 (L1–L4), 0.38 ± 1 (total hip), and 0.52 ± 1.03 (total body). BMD reduction less than −1 was found in 7 (26.9%) CF patients. Vitamin D deficiency in 20 CF patients (76.9%) tended to be lower in CF patients with low BMD. BMD was significantly correlated with FEV1; however, no significant association was observed withP. aeruginosacolonization.Conclusion. BMD reduction does occur in patients with mild CFTR mutation associated with pancreatic sufficiency.

Sign in / Sign up

Export Citation Format

Share Document