scholarly journals Mobile-Based Analysis of Malaria-Infected Thin Blood Smears: Automated Species and Life Cycle Stage Determination

Sensors ◽  
2017 ◽  
Vol 17 (10) ◽  
pp. 2167 ◽  
Author(s):  
Luís Rosado ◽  
José da Costa ◽  
Dirk Elias ◽  
Jaime Cardoso

2018 ◽  
Vol 82 (3) ◽  
pp. 283-295 ◽  
Author(s):  
Naveed Abbas ◽  
Tanzila Saba ◽  
Amjad Rehman ◽  
Zahid Mehmood ◽  
Hoshang kolivand ◽  
...  


2016 ◽  
Author(s):  
Vrushali Shah ◽  
Sarang Shankar Bhola


2021 ◽  
Author(s):  
Kokou S. Dogbevi ◽  
Paul Gordon ◽  
Kimberly L. Branan ◽  
Bryan Khai D. Ngo ◽  
Kevin B. Kiefer ◽  
...  

Effective staining of peripheral blood smears which enhances the contrast of intracellular components and biomarkers is essential for the accurate characterization, diagnosis, and monitoring of various diseases such as malaria.



1988 ◽  
Vol 13 (4) ◽  
pp. 5-13 ◽  
Author(s):  
Tapio Aittola




2018 ◽  
Vol 17 (1) ◽  
Author(s):  
Muneaki Hashimoto ◽  
Hirokazu Sakamoto ◽  
Yusuke Ido ◽  
Masato Tanaka ◽  
Shouki Yatsushiro ◽  
...  


2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Oscar Daniel Rivera Baena ◽  
Maria Valentina Clavijo Mesa ◽  
Carmen Elena Patino Rodriguez ◽  
Fernando Jesus Guevara Carazas

PurposeThis paper aims to determine the stage of the life cycle where the trucks of a waste collection fleet from a Colombian city are located through a reliability approach. The reliability analysis and the evaluation of curve of operational costs allow to know the moment in which it is necessary to make decisions regarding an asset, its maintenance or possible replacement.Design/methodology/approachFor a dataset presented as maintenance work orders, the time to failures (TTFs) for each vehicle in the fleet were calculated. Then, a probability density function for those TTFs was fitted to locate each vehicle in a region of the bathtub curve and to calculate the reliability of the whole fleet. A general functional analysis was also developed to understand the function of the vehicles.FindingsIt was possible to determine that the largest proportion of the fleet was in the final stage of the life cycle, in this sense, the entire fleet represent critical assets which in most of cases could be worth replacement or overhaul.Originality/valueIn this study, an address is exposed for the identification of critical equipment by reliability and statistical analysis. This analysis is also integrated with the maintenance management process. This is a broadly interested topic since it allows to support the maintenance and operational decision-making process, indicating the focus of resource allocation all over the entire asset life cycle.



Science ◽  
1930 ◽  
Vol 71 (1831) ◽  
pp. 134-135
Author(s):  
Chas. W. Rees


1994 ◽  
Vol 14 (5) ◽  
pp. 2975-2984
Author(s):  
H Charest ◽  
G Matlashewski

Leishmania protozoans are the causative agents of leishmaniasis, a major parasitic disease in humans. During their life cycle, Leishmania protozoans exist as flagellated promastigotes in the sand fly vector and as nonmotile amastigotes in the mammalian hosts. The promastigote-to-amastigote transformation occurs in the phagolysosomal compartment of the macrophage cell and is a critical step for the establishment of the infection. To study this cytodifferentiation process, we differentially screened an amastigote cDNA library with life cycle stage-specific cDNA probes and isolated seven cDNAs representing amastigote-specific transcripts. Five of these were closely related (A2 series) and recognized, by Northern (RNA) blot analyses, a 3.5-kb transcript in amastigotes and in amastigote-infected macrophages. Expression of the amastigote-specific A2 gene was induced in promastigotes when they were transferred from culture medium at 26 degrees C and pH 7.4 to medium at 37 degrees C and pH 4.5, conditions which mimic the macrophage phagolysosomal environment. A2 genes are clustered in tandem arrays, and a 6-kb fragment corresponding to a unit of the cluster was cloned and partially sequenced. An open reading frame found within the A2-transcribed region potentially encoded a 22-kDa protein containing repetitive sequences. The recombinant A2 protein produced in Escherichia coli cells was specifically recognized by immune serum from a patient with visceral leishmaniasis. The A2 protein repetitive element has strong homology with an S antigen of Plasmodium falciparum, the protozoan parasite responsible for malaria. Both the A2 protein of Leishmania donovani and the S antigen of P. falciparum are stage specific and developmentally expressed in mammalian hosts.



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