scholarly journals Paper-Based Competitive Immunochromatography Coupled with an Enzyme-Modified Electrode to Enable the Wireless Monitoring and Electrochemical Sensing of Cotinine in Urine

Sensors ◽  
2021 ◽  
Vol 21 (5) ◽  
pp. 1659
Author(s):  
Nutcha Larpant ◽  
Pramod K. Kalambate ◽  
Tautgirdas Ruzgas ◽  
Wanida Laiwattanapaisal
Keyword(s):  
Glucose Oxidase ◽  
Modified Electrode ◽  
Near Field ◽  
Electrochemical Measurement ◽  
Electrochemical Sensing ◽  
Urine Samples ◽  
Lateral Flow Strip ◽  
Wireless Monitoring ◽  
Sensing Platform ◽  
Combined Strategy

This paper proposes a combined strategy of using paper-based competitive immunochromatography and a near field communication (NFC) tag for wireless cotinine determination. The glucose oxidase labeled cotinine antibody specifically binds free cotinine in a sample, whereas the unoccupied antibody attached to BSA-cotinine at the test line on a lateral flow strip. The glucose oxidase on the strip and an assistant pad in the presence of glucose generated H2O2 and imposed the Ag oxidation on the modified electrode. This enabled monitoring of immunoreaction by either electrochemical measurement or wireless detection. Wireless sensing was realized for cotinine in the range of 100–1000 ng/mL (R2 = 0.96) in PBS medium. Undiluted urine samples from non-smokers exhibited an Ag-oxidation rate three times higher than the smoker’s urine samples. For 1:8 diluted urine samples (smokers), the proposed paper-based competitive immunochromatography coupled with an enzyme-modified electrode differentiated positive and negative samples and exhibited cotinine discrimination at levels higher than 12 ng/mL. This novel sensing platform can potentially be combined with a smartphone as a reader unit.

Porous Carbon Modified Electrode as a Highly-sensitive Electrochemical Sensing Platform for Salvianolic Acid B

2015 ◽  
Vol 28 (1) ◽  
pp. 235-242
Author(s):  
Qin Cheng ◽  
Miao Zhang ◽  
Wensheng Huang ◽  
Piaopiao Wei ◽  
Kangbing Wu
Keyword(s):  
Modified Electrode ◽  
Porous Carbon ◽  
Salvianolic Acid B ◽  
Electrochemical Sensing ◽  
Salvianolic Acid ◽  
Sensing Platform ◽  
Highly Sensitive

scholarly journals Polyphenol oxidase/gold nanoparticles/mesoporous carbon-modified electrode as an electrochemical sensing platform for rutin in dark teas

RSC Advances ◽  
2019 ◽  
Vol 9 (4) ◽  
pp. 2152-2155 ◽  
Author(s):  
Tongsheng Zhong ◽  
Qianqiong Guo ◽  
Zhifang Yin ◽  
Xiaoyan Zhu ◽  
Rong Liu ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Modified Electrode ◽  
Polyphenol Oxidase ◽  
Mesoporous Carbon ◽  
Electrochemical Sensing ◽  
Sensing Platform ◽  
Great Surface ◽  
Enhanced Conductivity ◽  
Great Surface Area

By virtue of great surface area of mesoporous carbon, enhanced conductivity of AuNPs, and good electrochemical response of polyphenol oxidase to rutin, a PPO/AuNPs/FDU-15-modified electrode was used for the determination of rutin in dark teas.

scholarly journals Spot on Gold Nanoparticles/Silica Modified Electrode for Rapid Sensitive Determination of Dinoprostone

2019 ◽  
pp. 17-22 ◽  
Author(s):  
Shimaa A Atty ◽  
Mohammed Walash ◽  
Safaa Toubar ◽  
Maha M AbouEl-Alamin ◽  
Maha A Elabd ◽  
...  
Keyword(s):  
Modified Electrode ◽  
Pharmaceutical Preparation ◽  
Electrochemical Sensing ◽  
Modified Carbon Paste Electrode ◽  
Official Method ◽  
Carbon Paste ◽  
Experimental Conditions ◽  
Sensing Platform ◽  
Sensitive Determination

A novel simple and selective electrochemical procedure is utilized for the determination of Dinoprostone (DIN) in drug substance and pharmaceutical preparation with good recovery and without interference with other excipient. Herein, the electrochemical sensing platform based upon preparing gold nanoparticle sensor on silica modified carbon paste electrode. The surface morphology of the modified electrode was characterized by scanning electron microscope. Different experimental conditions, including electrode composition, effect of pH and scan rate were estimated carefully by cyclic voltammetry to obtain the highest electrochemical response. By using square wave voltammetry a good linear response was obtained in the range of, 2 x 10-5-4 x10-4 mol L-1, and 2 x 10-7-1.6 x 10-4 mol L-1, with low detection limit of 5 x 10-6 mol L-1, and 4.9 x 10-8 mol L-1 by CPE and GNP/SMCPE respectively. The obtained results are in good agreement with those obtained by official method. No electrochemical method was reported before for determination of DIN. The developed method was simple, rapid, economic and challenging to green analytical chemistry.

Copper sulfide nano-globules reinforced electrodes for high-performance electrochemical determination of toxic pollutant hydroquinone

2021 ◽  
Vol 45 (6) ◽  
pp. 3215-3223
Author(s):  
Selvarasu Maheshwaran ◽  
Ramachandran Balaji ◽  
Shen-Ming Chen ◽  
Ray Biswadeep ◽  
Vengudusamy Renganathan ◽  
...  
Keyword(s):  
Copper Sulfide ◽  
High Performance ◽  
Electrochemical Determination ◽  
Electrochemical Sensing ◽  
Sensing Platform ◽  
Toxic Pollutant

A high-performance electrochemical sensing platform based on CuS nano-globules is efficiently developed.

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