APPLYING MIDDLE CELEBRAL ARTERY DOPPLER ON PREDICTING OF FETAL DISTRESS ASSOCIATED WITH PREECLAMPSIA

2015 ◽  
pp. 61-65
Author(s):  
Thi Duyen Hai Phan ◽  
Tran Thao Nguyen Nguyen ◽  
Lam Huong Le

Objectives: To study the value of the Doppler resistance index of middle celebral artery and its correlation to predict fetal distress associated with pre-eclampsia. Methods: 102 patients with pre-eclampsia at Obs. & Gyn. Department – Hue Central Hospital were taken by a prospective cohort study. Results: Mean of RI middle cerebral artery was 0.70 ± 0.08 (0.49-0.92, 95% CI). The rate doppler resistance index of middle cerebral/umblical artery < 1 was 27/102 (26.4%). There was no correlation between resitance index of middle cerebral artery and fetal distress status. The rate doppler resistance index of middle cerebral/umblical artery had a close relation to abnormal fetal after delivery. Conclusion: The doppler resistance index of middle cerebral artery was not a predict factor of fetal distress associated with pre-eclampsia. Key words: Doppler, middle celebral artery, fetal distress, pre-eclampsia

2016 ◽  
pp. 57-64
Author(s):  
Thi Linh Giang Truong ◽  
Vu Quoc Huy Nguyen ◽  
Quang Vinh Truong ◽  
Van Duc Vo

Background: Study on the correlation between the values of the Uterine Doppler with the type of preeclamsia and using uterine Doppler and predict fetal distress. Methods: Study on 116 patients with pre-eclampsia at Obs. & Gyn. Department - Hue Central Hospital were taken by an prospective cohort study. Results: There was correlation between morphology of uterine Doppler waves with the type of preeclamsia and fetal distress. Among 46 patients with server preeclamsia, the rate of abnormal of waves uterine Doppler is 78,2 %, and the rate of abnormal of waves uterine Doppler is 22% and fetal. This research also evaluate the relation between uterine Doppler with the fetal distress. The group patients with fetal distress also have the rate of abnormal uterine Doppler is 86,6% and the rate of nomal uterine dopple is 13,4 %. Conclusion: There was the correlation between the values of the Uterine Doppler with the type of preeclamsia and predict fetal distress. The value of uterine Doppler ultrasound can be predict the ricks happening for mother and fetal distress with preeclampsia. Key words: Doppler ultrosound, uterine Doppler, fetal distress, preeclampsia, IUGR.


2019 ◽  
Vol 37 (05) ◽  
pp. 491-496
Author(s):  
Ahmed M. Maged ◽  
Amira Y. Shoab ◽  
Eman A. Hussein ◽  
Ahmed H. Alsawaf ◽  
Doaa S. Mahmoud ◽  
...  

Abstract Objective This study aimed to evaluate the effect of vaginal progesterone (P) administration during the second and third trimesters of pregnancy on Doppler velocimetry of uterine, umbilical, and middle cerebral vessels. Study Design A prospective cohort study conducted on 80 women at risk for preterm labor. Uterine artery, umbilical artery, and middle cerebral artery (MCA) Doppler indices were measured before and after 1 week of administration of 200 mg twice daily vaginal P. The primary outcome parameter was the change of MCA pulsatility index (PI) after P administration. Secondary outcomes included changes in uterine artery and umbilical artery Doppler measurement. Results There was no significant changes of umbilical artery resistance index (RI) (0.69 ± 0.049 vs. 0.68 ± 0.041), umbilical artery PI (1.14 ± 0.118 vs. 1.11 ± 0.116), uterine artery RI (0.66 ± 0.12 vs. 0.66 ± 0.107), uterine artery PI (1.00 ± 0.26 vs. 1.016 ± 0.24), and MCA PI (1.27 ± 0.18 vs. 1.26 ± 0.23) measurements before and after 1 week of P administration, respectively. Conclusion Administration of vaginal P has no significant effects on uterine artery, umbilical artery, and MCA Doppler indices.


2014 ◽  
pp. 9-18
Author(s):  
Thi Linh Giang Truong ◽  
Vu Quoc Huy Nguyen

Background: Assessment of fetal health plays the most important role in prenatal care because of influence of the prediction of gestational outcome. One of the main aims of routine antenatal care is to identify the ‘ at risk ‘ fetus in order to apply clinical interventions which could results in reduced perinatal morbidity and mortality. Doppler ultrasound is a non invasive technique whereby the movement of blood is studied by detecting the change in frequence of reflected sound, Doppler blood flow velocity waves form of fetal side (umbilical artery, middle cerebral artery ...) and maternal side ( uterine arteries) are discussed and monograms for routine practice are presented. Recently this method is important tool for qualifying high risk pregnancies and help early forecasts the health of the babies and mothers disorder. Doppler sonography in obstetrics is a widely accepted functional method of examining the prediction of gestational outcome. Key words: Doppler, umbilical artery, middle cerebral artery, uterine arteries


2012 ◽  
Vol 2 (2) ◽  
pp. 77-80
Author(s):  
Md Abu Taher ◽  
Nuzhat Tasmin ◽  
AS Mohiuddin ◽  
Md Mohit Ul Alam ◽  
Md Mofazzal Sharif ◽  
...  

This observational type of descriptive study was carried out in the Department of Radiology and Imaging, BIRDEM selecting 70 Bangladeshi pregnant babies with the aim to find out the normogram of foetal middle cerebral artery Doppler flow velocity indices and correlation between Doppler flow velocity indices [Resistance Index (RI), Pulsatility Index (PI), Systolic/Diastolic ratio (S/D) & Peak Systolic Velocity (PSV)] of foetal middle cerebral artery and gestational age in normal pregnancies of 20 to 40 weeks. It was observed that RI, PI and S/D were decreased with the advance of gestational age but PSV was increases with the advance of gestational age. Statistical analyses showed there were significant difference between mean PSV, RI and PI before and after 25 weeks of gestation. No significant difference was found between mean S/D before and after 25 weeks of gestation. It was observed from Correlation analysis between Doppler indices with independent gestational age that all the Doppler indices of foetal middle cerebra artery was positively correlated with the whole gestation period. The statistical analysis showed only PSV and RI were significantly correlated with the gestational age. Simple regression analysis between dependent Doppler index with independent gestational age before and after 25 weeks revealed that all the Doppler indices had positive relationship with the corresponding gestational age but relationship between PSV and PI (before 25 weeks) with their corresponding gestational ages were only statistically significant.DOI: http://dx.doi.org/10.3329/birdem.v2i2.12306 Birdem Med J 2012; 2(2) 77-80


2021 ◽  
Author(s):  
Muhammad Shahzad ◽  
Zia UlHaq ◽  
Simon C Andrews

Introduction: Tuberculosis (TB) caused by Mycobacterium tuberculosis is a common infectious disease associated with significant morbidity and mortality, especially in low and middle-income countries. Successful treatment of the disease requires prolonged intake (6 to 8 months) of multiple antibiotics with potentially detrimental consequences on the composition and functional potential of the human microbiome. The protocol described in the current study aims to identify microbiome (oral and gut) signatures associated with TB pathogenesis, treatment response and, outcome in humans. Methods and analysis: Four hundred and fifty, newly diagnosed TB patients from three district levels (Peshawar, Mardan, Swat) TB diagnosis and treatment centers will be recruited in this non-interventional, prospective cohort study and will be followed and monitored until treatment completion. Demographic and dietary intake data, anthropometric measurement and blood, stool and salivary rinse samples will be collected at baseline, day 15, month-2 and end of the treatment. Additionally, we will recruit age and sex-matched healthy controls (n=30). Blood sampling will allow monitoring of the immune response during the treatment, while salivary rinse and fecal samples will allow monitoring of dynamic changes in oral and gut microbiome diversity. Within this prospective cohort study, a nested case-control study design will be conducted to assess perturbations in oral and gut microbiome diversity (microbial dysbiosis) and immune response and compare between the patients groups (treatment success vs failure). Ethics and dissemination The study has received ethics approval from the Ethic Board of Khyber Medical University Peshawar, and administrative approval from the Provincial TB Control Program of Khyber Pakhtunkhwa, Pakistan. The study results will be presented at national and international conferences and published in peer-reviewed journals. Trial registration number: NCT04985994; pre-results


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