APPLYING VALUE UTERINE DOPPLER ASSOCIATED WITH PREECLAMPSIA

2016 ◽  
pp. 57-64
Author(s):  
Thi Linh Giang Truong ◽  
Vu Quoc Huy Nguyen ◽  
Quang Vinh Truong ◽  
Van Duc Vo
Keyword(s):  
Cohort Study ◽  
Key Words ◽  
Doppler Ultrasound ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Fetal Distress ◽  
Central Hospital ◽  
Study Results ◽  
Key Words Doppler

Background: Study on the correlation between the values of the Uterine Doppler with the type of preeclamsia and using uterine Doppler and predict fetal distress. Methods: Study on 116 patients with pre-eclampsia at Obs. & Gyn. Department - Hue Central Hospital were taken by an prospective cohort study. Results: There was correlation between morphology of uterine Doppler waves with the type of preeclamsia and fetal distress. Among 46 patients with server preeclamsia, the rate of abnormal of waves uterine Doppler is 78,2 %, and the rate of abnormal of waves uterine Doppler is 22% and fetal. This research also evaluate the relation between uterine Doppler with the fetal distress. The group patients with fetal distress also have the rate of abnormal uterine Doppler is 86,6% and the rate of nomal uterine dopple is 13,4 %. Conclusion: There was the correlation between the values of the Uterine Doppler with the type of preeclamsia and predict fetal distress. The value of uterine Doppler ultrasound can be predict the ricks happening for mother and fetal distress with preeclampsia. Key words: Doppler ultrosound, uterine Doppler, fetal distress, preeclampsia, IUGR.

APPLYING MIDDLE CELEBRAL ARTERY DOPPLER ON PREDICTING OF FETAL DISTRESS ASSOCIATED WITH PREECLAMPSIA

2015 ◽  
pp. 61-65
Author(s):  
Thi Duyen Hai Phan ◽  
Tran Thao Nguyen Nguyen ◽  
Lam Huong Le
Keyword(s):  
Cohort Study ◽  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Prospective Cohort ◽  
Resistance Index ◽  
Fetal Distress ◽  
Close Relation ◽  
Central Hospital ◽  
Study Results ◽  
Key Words Doppler

Objectives: To study the value of the Doppler resistance index of middle celebral artery and its correlation to predict fetal distress associated with pre-eclampsia. Methods: 102 patients with pre-eclampsia at Obs. & Gyn. Department – Hue Central Hospital were taken by a prospective cohort study. Results: Mean of RI middle cerebral artery was 0.70 ± 0.08 (0.49-0.92, 95% CI). The rate doppler resistance index of middle cerebral/umblical artery < 1 was 27/102 (26.4%). There was no correlation between resitance index of middle cerebral artery and fetal distress status. The rate doppler resistance index of middle cerebral/umblical artery had a close relation to abnormal fetal after delivery. Conclusion: The doppler resistance index of middle cerebral artery was not a predict factor of fetal distress associated with pre-eclampsia. Key words: Doppler, middle celebral artery, fetal distress, pre-eclampsia

scholarly journals Exploring the Role of Microbiome in Susceptibility, Treatment Response and Outcome among Tuberculosis Patients from Pakistan; Study Protocol for a Prospective Cohort Study (Micro-STOP)

2021 ◽  
Author(s):  
Muhammad Shahzad ◽  
Zia UlHaq ◽  
Simon C Andrews
Keyword(s):  
Immune Response ◽  
Cohort Study ◽  
Treatment Response ◽  
Prospective Cohort Study ◽  
Gut Microbiome ◽  
Prospective Cohort ◽  
Treatment Success ◽  
Anthropometric Measurement ◽  
Microbiome Diversity ◽  
Study Results

Introduction: Tuberculosis (TB) caused by Mycobacterium tuberculosis is a common infectious disease associated with significant morbidity and mortality, especially in low and middle-income countries. Successful treatment of the disease requires prolonged intake (6 to 8 months) of multiple antibiotics with potentially detrimental consequences on the composition and functional potential of the human microbiome. The protocol described in the current study aims to identify microbiome (oral and gut) signatures associated with TB pathogenesis, treatment response and, outcome in humans. Methods and analysis: Four hundred and fifty, newly diagnosed TB patients from three district levels (Peshawar, Mardan, Swat) TB diagnosis and treatment centers will be recruited in this non-interventional, prospective cohort study and will be followed and monitored until treatment completion. Demographic and dietary intake data, anthropometric measurement and blood, stool and salivary rinse samples will be collected at baseline, day 15, month-2 and end of the treatment. Additionally, we will recruit age and sex-matched healthy controls (n=30). Blood sampling will allow monitoring of the immune response during the treatment, while salivary rinse and fecal samples will allow monitoring of dynamic changes in oral and gut microbiome diversity. Within this prospective cohort study, a nested case-control study design will be conducted to assess perturbations in oral and gut microbiome diversity (microbial dysbiosis) and immune response and compare between the patients groups (treatment success vs failure). Ethics and dissemination The study has received ethics approval from the Ethic Board of Khyber Medical University Peshawar, and administrative approval from the Provincial TB Control Program of Khyber Pakhtunkhwa, Pakistan. The study results will be presented at national and international conferences and published in peer-reviewed journals. Trial registration number: NCT04985994; pre-results

scholarly journals Associations between the Grade of Placental Maturity at Third Trimester Ultrasound and Maternofetal Outcomes at the Maternity of the Yaoundé Central Hospital: A Prospective Cohort Study

2015 ◽  
Vol 9 (3) ◽  
pp. 230-233
Author(s):  
Jeanne Hortence Fouedjio ◽  
Florent Ymele Fouelifack ◽  
Jovanny Tsuala Fouogue ◽  
Thierry Tetka Tetka
Keyword(s):  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Obstet Gynecol ◽  
Close Monitoring ◽  
Central Hospital ◽  
Third Trimester ◽  
Grade 3 ◽  
Meconium Stained Amniotic Fluid ◽  
Singleton Pregnancies

ABSTRACT Background Placental maturity assessed by ultrasound has been classified into 3 grades by Grannum. Grade 3 before the 36th week of pregnancy is associated with adverse maternofetal morbidity. We sought to determine the prevalence of grade 3 placenta between the 34th and the 36th week of pregnancy and to assess its impact on maternofetal outcomes in Cameroon. Materials and methods This prospective cohort study was conducted from January 2012 to July 2013 in the maternity unit of the Yaoundé Central Hospital. Results One hundred and two women with singleton pregnancies between the 34th and 36th weeks were included. Grade 3 placenta accounted for 5.9% of our sample. Grade 3 was significantly associated with the following: anterior location of the placenta (RR = 5.36; 95% CI: 1.36–9.62; p = 0.03), pre-eclampsia (RR = 12; 95% CI: 3.52–20.8; p = 0,003), meconium-stained amniotic fluid (RR = 4.32; 95% CI: 1.65–11.51; p = 0.04) and intrauterine growth restriction (RR = 2.43; 95% CI: 1.33–15.6; p = 0.007). Conclusion Grade 3 placental maturity before the 36th week of pregnancy is significantly associated with some maternal and fetal morbidities. Therefore, it warrants close monitoring to detect and avoid complications. How to cite this article Hortence FJ, Florent FY, Fouogue JT, Thierry TT. Associations between the Grade of Placental Maturity at Third Trimester Ultrasound and Maternofetal outcomes at the Maternity of the Yaoundé Central Hospital: A Prospective Cohort Study. Donald School J Ultrasound Obstet Gynecol 2015;9(3):230-233.

scholarly journals Self-reported sleep in late pregnancy in relation to birth size and fetal distress: the E Moe, Māmā prospective cohort study

BMJ Open ◽  
2015 ◽  
Vol 5 (10) ◽  
pp. e008910 ◽  
Author(s):  
Laura D Howe ◽  
T Leigh Signal ◽  
Sarah-Jane Paine ◽  
Bronwyn Sweeney ◽  
Monique Priston ◽  
...  
Keyword(s):  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Late Pregnancy ◽  
Fetal Distress ◽  
Birth Size

scholarly journals Predictors of physical activity levels in children and adolescents with cerebral palsy: clinical cohort study protocol

BMJ Open ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. e047522
Author(s):  
Christina Esmann Fonvig ◽  
Jens Troelsen ◽  
Ulrike Dunkhase-Heinl ◽  
Jens Martin Lauritsen ◽  
Anders Holsgaard-Larsen
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Cerebral Palsy ◽  
Cohort Study ◽  
Children And Adolescents ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Increased Risk ◽  
Study Results

IntroductionChildren and adolescents with cerebral palsy may be trapped in a vicious circle of low physical fitness, resulting in deconditioning that causes a further decrease in physical activity (PA), a lower quality of life and an increased risk of developing non-communicable diseases. Therefore, establishing a healthy and active lifestyle during childhood is even more important for individuals with a disability. However, the factors that influence habitual PA in children and adolescents with cerebral palsy remain unknown.The present protocol outlines a prospective cohort study with the aim of investigating potential predictors of habitual PA in children and adolescents with cerebral palsy in order to provide evidence for optimising PA levels and associated overall health.Methods and analysisThis prospective cohort study will enrol participants with cerebral palsy between the ages of 8 and 15 years at Gross Motor Function Classification System levels I–III. Using a modified version of the International Classification of Functioning, Disability and Health model as a conceptual analytical framework, the analysis will be divided into six components and will provide predictors for habitual PA measured by accelerometry. The potential predictive variables are registry data on physical function (Danish Cerebral Palsy Follow-Up Programme); validated proxy-reported questionnaires on quality of life (Paediatric Quality of Life Inventory), overall health, pain and participation in daily activities (Paediatric Outcomes Data Collection Instrument) and supplementary questions regarding sleep, screen time and socioeconomic status.Ethics and disseminationThe project is approved by the Danish Data Protection Agency (19/16396) and has been declared not notifiable by the Regional Committee on Health Research Ethics, cf. Committee Act Art. 14, paragraph 1 (S-20192000-23). The study results will be published in international peer-reviewed journals, presented at international conferences, and published in a PhD dissertation.Trial registration numberNCT04614207.

Unlikely association between Kawasaki disease and intracranial aneurysms: a prospective cohort study

2019 ◽  
Vol 23 (5) ◽  
pp. 593-596
Author(s):  
Dan Laukka ◽  
Melissa Rahi ◽  
Riitta Parkkola ◽  
Tero Vahlberg ◽  
Arttu Rintala ◽  
...  
Keyword(s):  
Cohort Study ◽  
Kawasaki Disease ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Intracranial Aneurysms ◽  
Hospital District ◽  
Arterial Lesions ◽  
Study Results ◽  
History Of ◽  
The Mean

OBJECTIVEKawasaki disease (KD) is a vasculitis that can cause aneurysm formation in coronary arteries and, more rarely, in peripheral arteries. A possible connection between KD and intracranial aneurysms is unclear. The purpose of this study was to determine if KD is associated with intracranial aneurysms.METHODSIn this prospective cohort study, all patients hospitalized and diagnosed with KD in the authors’ hospital district area in the period from 1978 to 1995 were identified. Patients with a current age ≥ 25 years and a history of KD in childhood were included in the study, which was conducted between 2016 and 2017. Magnetic resonance angiography (MRA) of the brain was performed in all patients.RESULTSForty patients (25 males), whose mean age was 33.5 ± 3.9 years (mean ± standard deviation), were eligible for study inclusion. The mean age at KD diagnosis was 3.9 ± 3.1 years, and the mean follow-up was 29.5 ± 4.3 years. Six patients (15%) had coronary arterial lesions during the acute illness of KD. None of the patients (0%) had intracranial aneurysms on brain MRA, which is significantly under the prevalence of 10% (95% CI 0%–8.8%, p = 0.03) that is the recommended limit for intracranial aneurysm screening.CONCLUSIONSThe study results suggest that KD is not associated with an increased prevalence of intracranial aneurysms and that screening for intracranial aneurysms is not warranted in patients with a history of KD.

Single versus combination tocolytic regimen in the prevention of preterm births in women: a prospective cohort study

2015 ◽  
Vol 43 (4) ◽  
Author(s):  
Qiu Ju Ng ◽  
Muhammad Fairuz Bin Abdul Rahman ◽  
May Li Lim ◽  
Jing Jye Chee ◽  
Kok Hian Tan
Keyword(s):  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Preterm Labor ◽  
Preterm Births ◽  
Combination Regimen ◽  
Study Results ◽  
The Mean ◽  
Group 2 ◽  
Single Versus

AbstractOur objective is to compare the efficacy of combination regimen (salbutamol and nifedipine) against single regimen (nifedipine alone) in preventing preterm births among women with preterm labor.A total of 76 women with gestational age (GA) ranging from 24+0 to 35+6 weeks, who sought treatment for preterm labor with or without cervical dilatation, were recruited for the prospective cohort study. Of these, 38 (50%) had single tocolytic regimen and 38 (50%) had combination tocolytic regimen. The mean GAs at admission were similar for both groups at 31 weeks (±2.93) for Group 1 and 30.9 weeks (±2.88) for Group 2 (P=0.873). The mean GAs at delivery were 37.8 weeks (±1.98) for the single regimen and 36.2 weeks (±3.26) for the combined regimen (P=0.011). The mean tocolytic to delivery interval for the single regimen was longer at 6.74 weeks (±3.13) as compared with 5.21 weeks (±3.61) for the combination regimen (P<0.05). Those on the combination regimen complained of more adverse effects (P<0.001).Our study results suggested that the use of nifedipine as a single tocolytic regimen is as effective as the combination regimen in the delay of preterm births and has much less side effects. Hence, we recommend the sole use of nifedipine for the management of preterm labor.

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