Faculty Opinions recommendation of Direct measurement of the thermodynamic parameters of amyloid formation by isothermal titration calorimetry.

Author(s):  
George Perry
2004 ◽  
Vol 279 (53) ◽  
pp. 55308-55314 ◽  
Author(s):  
József Kardos ◽  
Kaori Yamamoto ◽  
Kazuhiro Hasegawa ◽  
Hironobu Naiki ◽  
Yuji Goto

2016 ◽  
Vol 46 (8) ◽  
pp. 1491-1497
Author(s):  
Monique Barreto Santos ◽  
Bernardo de Sá Costa ◽  
Edwin Elard Garcia Rojas

ABSTRACT: The interactions between biological macromolecules have been important for biotechnology, but further understanding is needed to maximize the utility of these interactions. Calorimetric techniques provide information regarding these interactions through the thermal energy that is produced or consumed during interactions. Notable techniques include differential scanning calorimetry, which generates a thermodynamic profile from temperature scanning, and isothermal titration calorimetry that provide the thermodynamic parameters directly related to the interaction. This review described how calorimetric techniques can be used to study interactions between proteins and polysaccharides, and provided valuable insight into the thermodynamics of their interaction.


2016 ◽  
Vol 45 (43) ◽  
pp. 17216-17222 ◽  
Author(s):  
Seraj A. Ansari ◽  
Prasanta K. Mohapatra ◽  
Willem Verboom ◽  
Linfeng Rao

Isothermal titration calorimetry has been used for the direct measurement of the enthalpy of extraction (ΔHextr) of metal ions in a solvent extraction process.


2013 ◽  
Vol 172 ◽  
pp. 61-67 ◽  
Author(s):  
Saori Hayashi ◽  
Jun Tamogami ◽  
Takashi Kikukawa ◽  
Haruka Okamoto ◽  
Kazumi Shimono ◽  
...  

2019 ◽  
Vol 2 (1) ◽  
Author(s):  
Yi-Yang Zhan ◽  
Qi-Chun Jiang ◽  
Kentaro Ishii ◽  
Takuya Koide ◽  
Osamu Kobayashi ◽  
...  

AbstractTrue understanding of dispersion interaction in solution remains elusive because of difficulty in the precise evaluation of its interaction energy. Here, the effect of substituents with different polarizability on dispersion interactions in water is discussed based on the thermodynamic parameters determined by isothermal titration calorimetry for the formation of discrete aggregates from gear-shaped amphiphiles (GSAs). The substituents with higher polarizability enthalpically more stabilize the nanocube, which is due to stronger dispersion interactions and to the hydrophobic effect. The differences in the thermodynamic parameters for the nanocubes from the GSAs with CH3 and CD3 groups are also discussed to lead to the conclusion that the H/D isotope effect on dispersion interactions is negligibly small, which is due to almost perfect entropy-enthalpy compensation between the two isotopomers.


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