Faculty Opinions recommendation of Long-term follow-up of type II endoleak embolization reveals the need for close surveillance.

ABSTRACT Background Achalasia is a chronic disease that can be managed with effective endoscopic modalities. Aim To evaluate the effectiveness of single setting of pneumatic balloon dilatation for achalasia and assess the long-term success and outcomes. Materials and methods This is a retrospective study of all achalasia patients who underwent pneumatic balloon dilatation at our institute. Patients who could be contacted were inquired regarding their symptoms and dysphagia-free interval after dilatation. Results A total of 72 patients were enrolled. Out of this, 14 patients lost to follow-up. Mean age of 58 patients was 45.02 ± 16.51 years. Male:female ratio was 13:16. Mean predilatation Eckardt score was 7.16 ± 0.834. Type I achalasia was present in 10 (17.2%), type II in 44 (75.9%), type III in 4 (6.9%). Predilatation basal integrated relaxation pressure (IRP) was 28.14 ± 14.76 mm Hg. Postdilatation Eckardt score was 2.40 ± 1.67. Postdilatation dysphagia-free interval was 17.28 ± 6.70 months. A total of 9 patients (15.51%) failed to respond to first dilatation and 49 (84.48%) patients benefited from single setting of pneumatic dilatation. Esophageal perforation occurred in 2/58 (3.44%). We did not find any significant difference in gender distribution, age of presentation, duration of symptom, pre- and postdilatation Eckardt score, type of achalasia, and basal IRP on manometry between type of achalasia. Postdilatation dysphagia-free interval in type II achalasia (18.09 ± 5.976 months) was more than types I and III achalasia cardia (p = 0.066), which showed trend toward significance. Conclusion Pneumatic balloon dilatation of achalasia cardia is a highly effective endoscopic procedure with minimal complications and mortality. Even the single setting of dilatation can have long-lasting dysphagia-free interval. How to cite this article Gupta SJ, Gaikwad NR, Samarth AR, Gattewar SR. Pneumatic Balloon Dilatation for Achalasia Cardia: Outcome, Complications, Success, and Long-term Follow-up. Euroasian J Hepato-Gastroenterol 2017;7(2):138-141.

Download Full-text

Tibial Agenesis: A New Rationale in Management of Type II—Report of Three Cases with Long-Term Follow-Up

Journal of Pediatric Orthopaedics ◽

10.1097/01241398-199003000-00012 ◽

1990 ◽

Vol 10 (2) ◽

pp. 198-201 ◽

Cited By ~ 16

Author(s):

Nando de Sanctis ◽

Emilio Razzano ◽

Raffaele Scognamiglio ◽

Antonetta Nunziata Rega

Keyword(s):

Type Ii ◽

Long Term Follow Up

Download Full-text

Long-term progression in type II spinal muscular atrophy

Neurology ◽

10.1212/wnl.0000000000008166 ◽

2019 ◽

Vol 93 (13) ◽

pp. e1241-e1247 ◽

Cited By ~ 7

Author(s):

Eugenio Mercuri ◽

Simona Lucibello ◽

Maria Carmela Pera ◽

Sara Carnicella ◽

Giorgia Coratti ◽

...

Keyword(s):

Spinal Muscular Atrophy ◽

Noninvasive Ventilation ◽

Muscular Atrophy ◽

Type Ii ◽

Piecewise Regression ◽

Long Term Follow Up ◽

Slope Change ◽

Changes Over Time

ObjectiveTo report the long-term progression in a cohort of patients with type II spinal muscular atrophy (SMA) assessed with the Hammersmith Functional Motor Scale–Expanded.MethodsSeventy-three patients (age 2.6–25 years) were included in the study. Twenty-eight of the 73 were first assessed before the age of 5 years and had been followed up for ≈5 years or longer. We observed an overall progression that was not linear. A piecewise regression analysis showed an improvement of scores in the younger patients with a point of slope change at ≈5 years of age, a decline between 5 and 13 years of age, and stability/slower decline after that.ResultsPatients with the lowest scores at baseline had the earliest onset of scoliosis and a higher need for noninvasive ventilation compared to those with higher scores. Our results confirm that on the long-term follow-up all patients with type II SMA show a clear and progressive decline.ConclusionThe severity of functional impairment at baseline can help to predict the magnitude of changes over time and the overall progression, including onset of scoliosis and need for noninvasive ventilation.

Download Full-text

S1252 Presentation and Long Term Follow-Up of Refractory Celiac Disease (RCD): Comparison of Rcd of Type I with Rcd of Type II

Gastroenterology ◽

10.1016/s0016-5085(08)60974-9 ◽

2008 ◽

Vol 134 (4) ◽

pp. A-211

Author(s):

Georgia Malamut ◽

Pauline Afchain ◽

Thierry Lecomte ◽

Dominique Cazals-Hatem ◽

Virginie Verkarre ◽

...

Keyword(s):

Celiac Disease ◽

Type I ◽

Type Ii ◽

Refractory Celiac Disease ◽

Long Term Follow Up

Download Full-text

Higher preprocedural fibrinogen levels are associated with aneurysm sac regression after EVAR

VASA ◽

10.1024/0301-1526/a000783 ◽

2019 ◽

Vol 48 (4) ◽

pp. 347-354

Author(s):

Mária Rašiová ◽

Martin Koščo ◽

Ľubomír Špak ◽

Matej Moščovič ◽

Jozef Židzik ◽

...

Keyword(s):

Multivariate Analysis ◽

Abdominal Aortic Aneurysm Repair ◽

Lower Probability ◽

Type Ii ◽

Type Ii Endoleak ◽

All Cause Mortality ◽

Long Term Follow Up ◽

Aneurysm Repair ◽

The Impact

Summary. Background: The aim of our study was to determine the diameter of the aneurysm sac 24 months after endovascular abdominal aortic aneurysm repair (EVAR); to identify factors associated with sac regression, and to determine the impact of sac regression on all-cause mortality during long-term follow-up. Patients and methods: We conducted a retrospective review of prospectively collected data from patients treated with EVAR between January, 2010 and July, 2016. Sac regression was defined as at least 5 mm decrease in aneurysm diameter in relation to the preprocedural diameter seen on computed tomography angiography. Sociodemographic information, comorbidities, treatment, laboratory parameters, selected anatomical and genetic factors were all analysed to determine their impact on sac regression. Results: During the study period, 124 patients with mean age of 71.2 ± 7.2 years met the inclusion criteria. Sac regression was found in 45.2% of patients. Higher preprocedural fibrinogen was found in patients with sac regression in comparison with patients with stable sac or sac expansion (3.84 g/l vs 3.47 g/l; p = 0.028). In multivariate analysis after adjustment for age, hypertension, sex, smoking, dyslipidaemia, volume and percentage of intraluminal thrombus higher fibrinogen was associated with an increased probability of sac regression (OR 2.47; 95% CI 1.29–4.72; p = 0.006). Persistent type II endoleak was associated with significantly lower probability of sac regression in univariate and multivariate analysis after adjustment for age, hypertension, sex, smoking and dyslipidaemia (OR 0.26; 95% CI 0.10–0.66; p = 0.004). Higher age was a significant predictor of sac regression in multivariate analysis after adjustment for hypertension, sex, smoking and dyslipidaemia (OR 1.07; 95% CI 1.02–1.14; p = 0.012). No difference was found between patient subgroups with and without sac regression in all-cause mortality during follow-up. Conclusions: Higher preprocedural fibrinogen, absence of persistent type II endoleak and higher age were predictive factors of aneurysm sac regression post-EVAR.

Download Full-text