Faculty Opinions recommendation of Abnormal high-density lipoprotein induces endothelial dysfunction via activation of Toll-like receptor-2.

Author(s):  
Andrew Gewirtz ◽  
Matam Vijay-Kumar (Vijay)
Immunity ◽  
2013 ◽  
Vol 38 (4) ◽  
pp. 754-768 ◽  
Author(s):  
Thimoteus Speer ◽  
Lucia Rohrer ◽  
Przemyslaw Blyszczuk ◽  
Rukshana Shroff ◽  
Kira Kuschnerus ◽  
...  

2019 ◽  
Vol 13 (4) ◽  
pp. 664-672.e1 ◽  
Author(s):  
Yuji Takaeko ◽  
Shogo Matsui ◽  
Masato Kajikawa ◽  
Tatsuya Maruhashi ◽  
Shinji Kishimoto ◽  
...  

Angiology ◽  
2017 ◽  
Vol 69 (1) ◽  
pp. 65-70 ◽  
Author(s):  
Nusret Acikgoz ◽  
Ertuğrul Kurtoğlu ◽  
Julide Yagmur ◽  
Yelda Kapicioglu ◽  
Mehmet Cansel ◽  
...  

Behçet disease (BD) is a multisystemic disorder characterized by endothelial dysfunction and inflammation. Monocyte to high-density lipoprotein cholesterol ratio (MHR) is a recently emerged indicator of inflammation and oxidative stress. Sixty patients with BD and 50 control individuals were included to investigate the relationship between MHR and endothelial dysfunction. Endothelial function was assessed by flow- and nitroglycerin-mediated dilatation technique (FMD and NMD, respectively). Serum high-sensitivity C-reactive protein (hsCRP) levels were measured in all study participants. The MHR and hsCRP levels were significantly higher in patients with active BD than in controls. Brachial artery FMD was significantly lower in patients with active BD than in controls. Brachial artery NMD was similar between groups. There was a strong inverse correlation between MHR and FMD and a strong positive correlation between MHR and serum hsCRP levels. Thus, elevated MHR may be a useful marker reflecting impaired endothelial function and systemic inflammation in patients with BD.


2009 ◽  
Vol 103 (9) ◽  
pp. 83B
Author(s):  
Seung Woon Rha ◽  
Soon Young Suh ◽  
Kanhaiya Lal Poddar ◽  
Kang Yin Chen ◽  
Yong Jian Li ◽  
...  

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