Faculty Opinions recommendation of Evolutionary origins of human herpes simplex viruses 1 and 2.

Author(s):  
Nancy Sawtell
2014 ◽  
Vol 31 (9) ◽  
pp. 2356-2364 ◽  
Author(s):  
Joel O. Wertheim ◽  
Martin D. Smith ◽  
Davey M. Smith ◽  
Konrad Scheffler ◽  
Sergei L. Kosakovsky Pond

1992 ◽  
Vol 13 (3) ◽  
pp. 107-111
Author(s):  
Ann M. Arvin ◽  
Charles G. Prober

There are six recognized members of the human herpes group of viruses. These include type 1 and type 2 herpes simplex viruses (HSV-1 and HSV-2), cytomegalovirus (CMV), Epstein-Barr virus (EBV), varicellazoster virus (VZV), and human herpes virus type 6 (HHV-6). These ubiquitous double-stranded DNA viruses are relatively large and lipid-enveloped. The capacity to induce a state of latency in the infected host has been proved for all of the herpes viruses. That is, after primary infection, the viruses remain forever with the host with the possibility for subsequent reactivations. The mechanisms of these reactivations are not understood completely. Both primary infections and recurrences may be associated with clinical illness or may be asymptomatic. To a large extent, the status of the host immune system determines the severity of the infection and the likelihood of recurrences. In general, infections are more severe and recurrences are more frequent in the most compromised hosts. This review focuses on HSV-1 and HSV-2, with emphasis on neonatal infections and maternal genital infections as a source of infection in the newborn. The clinical illnesses caused by HSV-1 and HSV-2 are usually quite distinct. HSV-1 is the predominant cause of oral, ocular, and central nervous system infections occurring after the neonatal period, and HSV-2 is the predominant cause of genital and neonatal infections.


2003 ◽  
Vol 71 (3) ◽  
pp. 423-428 ◽  
Author(s):  
Yongjiang Sun ◽  
Roy Kum Wah Chan ◽  
Suat Hoon Tan ◽  
Patricia Pei Lin Ng

2020 ◽  
Author(s):  
Amanda M. Casto ◽  
Meei-Li Huang ◽  
Hong Xie ◽  
Keith R. Jerome ◽  
Anna Wald ◽  
...  

AbstractHuman herpes simplex viruses (HSV) 1 and 2 are most often typed via molecular assays. Here we describe the first known case of HSV mistyping due to a previously undescribed HSV-1 x HSV-2 recombination event in UL27, the gene that encodes glycoprotein B. This is the first reported HSV interspecies recombination event impacting this gene, which is frequently used as a target for diagnostics and experimental therapeutics.


2010 ◽  
Vol 221 (2) ◽  
pp. 193-200 ◽  
Author(s):  
Kirk Jensen ◽  
Aneeta Patel ◽  
Alexander Larin ◽  
Victoria Hoperia ◽  
Motoyasu Saji ◽  
...  

2002 ◽  
Vol 9 (3) ◽  
pp. 716-719 ◽  
Author(s):  
Makoto Hirano ◽  
Shin Nakamura ◽  
Fusako Mitsunaga ◽  
Maki Okada ◽  
Shuya Shirahama ◽  
...  

ABSTRACT By adding betaine to the PCR mixture, we previously established a PCR method to amplify a DNA segment of the glycoprotein G gene of B virus (BV) derived from a rhesus macaque. We have found that DNA of other BV strains derived from cynomolgus, pigtail, and lion-tailed macaques can also serve as the template in our PCR assay. Under the same conditions no product was obtained with DNA of simian agent 8 of green monkeys and Herpesvirus papio 2 of baboons, or the human herpes simplex viruses types 1 and 2. Thus, this PCR method is useful to discriminate BV from other closely related primate alphaherpesviruses.


Sign in / Sign up

Export Citation Format

Share Document