Faculty Opinions recommendation of Enhanced effect of platelet-rich plasma containing a new carrier on hair growth.

2014 ◽  
Author(s):  
Juan Ferrando ◽  
José M Mir-Bonafé
Keyword(s):  
Hair Growth ◽  
Platelet Rich Plasma

Platelet‐rich plasma and microneedling improves hair growth in patients ofandrogenetic alopecia when used as an adjuvant to minoxidil

2019 ◽  
Vol 18 (5) ◽  
pp. 1330-1335 ◽  
Author(s):  
Abhijeet Kumar Jha ◽  
Keshavamurthy Vinay ◽  
Md Zeeshan ◽  
Prasoon Kumar Roy ◽  
R. K. P. Chaudhary ◽  
...  
Keyword(s):  
Hair Growth ◽  
Platelet Rich Plasma

Platelet-rich Plasma for Hair Growth

2019 ◽  
Vol 2 (1) ◽  
pp. 151-159
Author(s):  
Christina Wong ◽  
Shilpi Khetarpal
Keyword(s):  
Hair Growth ◽  
Platelet Rich Plasma

Stromal Vascular Fraction and Platelet-Rich Plasma Upregulate Vascular Endothelial Growth Factor Expression to Promote Hair Growth via the Wnt/β-Catenin Signaling Pathway

2019 ◽  
Vol 11 (12) ◽  
pp. 1685-1692
Author(s):  
Yarui Liu ◽  
Jindou Jiang ◽  
Yuan Ye ◽  
Zhehao Li ◽  
Meijun Tan ◽  
...  
Keyword(s):  
Vascular Endothelial Growth Factor ◽  
Growth Factor ◽  
Hair Follicle ◽  
Signaling Pathway ◽  
Hair Growth ◽  
Platelet Rich Plasma ◽  
Stromal Vascular Fraction ◽  
Follicle Cells ◽  
Vascular Endothelial ◽  
Endothelial Growth Factor

Androgenetic alopecia (AGA) is a hair loss disease. At present, use of the stromal vascular fraction (SVF) and platelet-rich plasma (PRP) are thought to be the novel, safe, and effective treatment options of AGA, but the mechanism by which SVF and PRP promote hair growth is unclear. Here, we investigated the mechanism underlying the effects of SVF and PRP on hair growth by in vitro culture and in vivo modeling. SVF and PRP promoted hair growth, as was evident from the observation and counting of hair on the back skin of nude mice using ImageJ software. SVF and PRP promoted hair growth, and SVF worked better. We performed nucleic acid extraction with nanomagnetic beads, and the protein levels were extracted with a bicinchoninic acid protein assay kit. The results of western blot analysis and quantitative polymerase chain reaction (qPCR) showed that both SVF and PRP promoted the expression of anti-apoptotic genes. The effect of SVF was better than that of PRP. The results of EdU and hematoxylin and eosin staining showed that SVF and PRP induced the proliferation of hair follicle cells. SVF exerted better effects on the proliferation of hair follicle cells than PRP. Enzyme-linked immunosorbent assay (ELISA) results showed that the expression of the proteins associated with the Wnt/β-catenin process, including vascular endothelial growth factor (VEGF), platelet-derived growth factor (PDGF), alkaline phosphatase (ALP), Wnt10b, and β-catenin, significantly increased in the SVF-treated and PRP-treated dermal/epidermal cells as compared with the control cells. Therefore, SVF and PRP increased the expression of VEGF and PDGF through the Wnt/β-catenin signaling pathway to promote hair growth. The effect of SVF on dermal cells/epidermal cells was stronger than that of PRP, and the difference was statistically significant (P < 0.05).

scholarly journals Platelet-rich plasma stimulates angiogenesis in mice which may promote hair growth

2017 ◽  
Vol 22 (1) ◽  
Author(s):  
Hanxiao Cheng ◽  
Jufang Zhang ◽  
Jinsheng Li ◽  
Ming Jia ◽  
Yuyan Wang ◽  
...  
Keyword(s):  
Hair Growth ◽  
Platelet Rich Plasma

scholarly journals Estudo do padrão de melhora da alopecia androgenética em pacientes com uso de microagulhamento associado a minoxidil e/ou plasma rico em plaquetas e mesoterapia / Study of the pattern of improvement in androgenetic alopecia in patients using microneedling associated with minoxidil and/or platelet-rich plasma and mesotherapy

2021 ◽  
Author(s):  
Mario Henrique Quim Ferreira ◽  
Isabella Bessegatto Rodrigues ◽  
Marcella Bessegatto Rodrigues
Keyword(s):  
Topical Application ◽  
Hair Loss ◽  
Conventional Therapy ◽  
Hair Growth ◽  
Platelet Rich Plasma ◽  
Hormonal Factors ◽  
Adjuvant Therapies ◽  
Rolling Method ◽  
The Subject ◽  
Slight Growth

Introdução: a alopécia ligada a fatores hormonais androgênicos é algo que há muito tempo tem sido alvo de estudos e aplicações de conhecimento científico em todo mundo. Este padrão de perda capilar, principalmente ligada ao sexo masculino dispõe de terapias que atualmente se limitam à interrupção da queda de fios com leve progressão de crescimento em alguns casos. Neste tocante, uma nova técnica de microagulhamento, com ou sem terapias adjuvantes, associado a métodos já consagradas como minoxidil tem levado o tratamento desta alteração estética para melhores níveis de resultado. Objetivo: conduzir uma investigação sobre os resultados atuais de pesquisas que envolvam o  microagulhamento associado ao uso de Minoxidil, plasma rico em plaquetas e/ou mesoterapia. Metodologia: foram feitas pesquisas no banco de dados da PubMed e Scielo em abril de 2021 buscando-se os termos “minoxidil AND microneedling”. Resultados e Discussões: os resultados obtidos têm convergido para a proposta de que a associação do método de rolagem (microagulhamento) com a aplicação tópica do vasodilatador (minoxidil) apresenta um padrão de crescimento capilar nunca alcançado pela terapia convencional disponível, e que, se acrescentar plasma rico em plaquetas e/ou soluções através da mesoterapia, os resultados podem ser ainda mais vantajosos.  Conclusão: novos estudos são necessários para abranger as vertentes ainda não elucidadas para o tratamento da alopecia, contudo, os resultados até aqui obtidos são promissores para o sucesso da reposição capilar.Palavras chave: Microagulhamento, Minoxidil, Alopecia AbstractIntroduction: alopecia linked to androgenic hormonal factors is something that has long been the subject of studies and knowledge applications worldwide. This pattern of hairloss, mainly related to males, has therapies that are currently limited to interruption of hair loss with slight growth progression in some cases. In this regard, a new microneedlingtechnique, with or without adjuvant therapies, associated with well-established methods such as minoxidil has led the treatment of this esthetic alteration to better levels of results. Objective: to conduct an investigation into the current results of research involving microneedling associated with the use of Minoxidil, platelet-rich plasma and/or mesotherapy. Methodology: searches were conducted in the PubMed and Scielo database in April 2021, searching for the terms “minoxidil AND microneedling”. Results and Discussions: the results obtained have converged to the proposal that the association of the rolling method(microneedling) with the topical application of a vasodilator (minoxidil) presents a pattern of hair growth never achieved by the available conventional therapy, and that, if addedplatelet-rich plasma and/or solutions through mesotherapy, the results can be even more advantageous. Conclusion: further studies are needed to cover aspects that have notyet been elucidated for the treatment of alopecia, however, the results obtained so far are promising for the success of hair replacement.Keywords: Microneedling, Minoxidil, Alopecia

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