Faculty Opinions recommendation of The prevalence and outcomes of frailty in older cancer patients: a systematic review.

2017 ◽  
Author(s):  
Siri Rostoft
Keyword(s):  
Systematic Review ◽  
Cancer Patients ◽  
Older Cancer Patients

A systematic review of the use and validation of health-related quality of life instruments in older cancer patients

2009 ◽  
Vol 45 (1) ◽  
pp. 19-32 ◽  
Author(s):  
Deborah Fitzsimmons ◽  
Jacqueline Gilbert ◽  
Frances Howse ◽  
Teresa Young ◽  
Juan-Ignacio Arrarras ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Cancer Patients ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Older Cancer Patients ◽  
Quality Of Life Instruments

Systematic Review and Meta-Analysis on the Associations of Polypharmacy and Potentially Inappropriate Medication With Adverse Outcomes in Older Cancer Patients

2020 ◽  
Author(s):  
Li-Ju Chen ◽  
Kira Trares ◽  
Dana Clarissa Laetsch ◽  
Thi Ngoc Mai Nguyen ◽  
Hermann Brenner ◽  
...  
Keyword(s):  
Systematic Review ◽  
Postoperative Complications ◽  
Cancer Patients ◽  
Meta Analysis ◽  
Inappropriate Medication ◽  
Adverse Outcomes ◽  
Potentially Inappropriate Medication ◽  
Significance Level ◽  
All Cause Mortality ◽  
Older Cancer Patients

Abstract Background Both polypharmacy and potentially inappropriate medication (PIM) intake are highly prevailing in older cancer patients. However, only studies on the association of polypharmacy and postoperative complications have been meta-analyzed previously. Methods A systematic review and a meta-analysis of prospective/retrospective observational studies reporting associations of polypharmacy or PIM with at least one out of five predefined adverse health outcomes in a population of older cancer patients (≥60 years) were carried out. PubMed and Web of Science were used to search for relevant studies published between January 1991 and March 2020. Data were pooled by adopting a random-effects model. Results Overall, 42 publications were included in the systematic review. Meta-analyses could be performed on 39 studies about polypharmacy and 13 studies about PIM. Polypharmacy was found to be statistically significantly associated with all-cause mortality (risk ratio [95% confidence interval]: 1.37 [1.25–1.50]), hospitalization (1.53 [1.37–1.71]), treatment-related toxicity (1.22 [1.01–1.47]), and postoperative complications (1.73 [1.36–2.20]). The association of polypharmacy with prolongation of hospitalization was not statistically significant at the p < .05 significance level (1.62 [0.98–2.66]). With respect to PIM, a statistically significant association with all-cause mortality (1.43 [1.08–1.88]) was observed but not with other adverse outcomes. Conclusions Polypharmacy was found to be associated with several adverse outcomes and PIM use with all-cause mortality in older cancer patients. However, these results should be interpreted with caution because about three-quarters of the studies identified did not adjust for comorbidity and are prone to confounding by indication.

Association between cachexia, chemotherapy and outcomes in older cancer patients: A systematic review

2017 ◽  
Vol 36 (6) ◽  
pp. 1473-1482 ◽  
Author(s):  
Philippe Caillet ◽  
Evelyne Liuu ◽  
Agathe Raynaud Simon ◽  
Marc Bonnefoy ◽  
Olivier Guerin ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cancer Patients ◽  
Older Cancer Patients

scholarly journals The prevalence and outcomes of frailty in older cancer patients: a systematic review

2015 ◽  
Vol 26 (6) ◽  
pp. 1091-1101 ◽  
Author(s):  
C. Handforth ◽  
A. Clegg ◽  
C. Young ◽  
S. Simpkins ◽  
M.T. Seymour ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cancer Patients ◽  
Older Cancer Patients

scholarly journals The effect of a geriatric evaluation on treatment decisions for older cancer patients – a systematic review

2013 ◽  
Vol 53 (3) ◽  
pp. 289-296 ◽  
Author(s):  
Marije E. Hamaker ◽  
Anandi H. Schiphorst ◽  
Daan ten Bokkel Huinink ◽  
Cees Schaar ◽  
Barbara C. van Munster
Keyword(s):  
Systematic Review ◽  
Cancer Patients ◽  
Treatment Decisions ◽  
Geriatric Evaluation ◽  
Older Cancer Patients

scholarly journals Cancer Pain and Depression: A Systematic Review of Age-Related Patterns

2007 ◽  
Vol 12 (3) ◽  
pp. 205-211 ◽  
Author(s):  
Lucia Gagliese ◽  
Lynn R Gauthier ◽  
Gary Rodin
Keyword(s):  
Systematic Review ◽  
Cancer Pain ◽  
Cancer Patients ◽  
Review Of The Literature ◽  
Exclusion Criteria ◽  
Age Related ◽  
Background Pain ◽  
Prevalence Of Depression ◽  
Older Cancer Patients ◽  
Quality And Outcomes

BACKGROUND: Pain is a common and debilitating symptom experienced by cancer patients of all ages. Cancer pain is associated with elevated levels of depression; however, age-related patterns in this relationship remain unclear. This information is important to provide effective palliation of pain and depression to the growing numbers of older cancer patients.OBJECTIVE: To provide a systematic review of the literature regarding age-related patterns in the intensity or prevalence of depression among cancer patients with pain.METHODS: Medical and psychological literature databases were searched to identify eligible studies. The methodological quality and outcomes of the studies were compiled and systematically reviewed.RESULTS: Five articles, describing four studies, met the inclusion and exclusion criteria. Due to high levels of cross-study methodological variability, a qualitative review was undertaken. Three of the four studies did not find evidence for age-related patterns in depression. The fourth study found that depression increased with age.CONCLUSION: The weight of the evidence suggests that younger and older cancer patients with pain report comparable levels of depression. However, this conclusion remains preliminary due to the methodological limitations of the available studies. Research is needed to more adequately address this important issue.

Sign in / Sign up

Export Citation Format

Share Document