scholarly journals Cancer Pain and Depression: A Systematic Review of Age-Related Patterns

2007 ◽  
Vol 12 (3) ◽  
pp. 205-211 ◽  
Author(s):  
Lucia Gagliese ◽  
Lynn R Gauthier ◽  
Gary Rodin

BACKGROUND: Pain is a common and debilitating symptom experienced by cancer patients of all ages. Cancer pain is associated with elevated levels of depression; however, age-related patterns in this relationship remain unclear. This information is important to provide effective palliation of pain and depression to the growing numbers of older cancer patients.OBJECTIVE: To provide a systematic review of the literature regarding age-related patterns in the intensity or prevalence of depression among cancer patients with pain.METHODS: Medical and psychological literature databases were searched to identify eligible studies. The methodological quality and outcomes of the studies were compiled and systematically reviewed.RESULTS: Five articles, describing four studies, met the inclusion and exclusion criteria. Due to high levels of cross-study methodological variability, a qualitative review was undertaken. Three of the four studies did not find evidence for age-related patterns in depression. The fourth study found that depression increased with age.CONCLUSION: The weight of the evidence suggests that younger and older cancer patients with pain report comparable levels of depression. However, this conclusion remains preliminary due to the methodological limitations of the available studies. Research is needed to more adequately address this important issue.

2020 ◽  
Vol 38 (8-9) ◽  
pp. 436-444 ◽  
Author(s):  
Anne Knisely ◽  
Jenny Wu ◽  
Samantha J. Kaplan ◽  
Zhen Ni Zhou ◽  
Alexander Melamed ◽  
...  

Sarcoma ◽  
2020 ◽  
Vol 2020 ◽  
pp. 1-7 ◽  
Author(s):  
Patrick Basile ◽  
Emily Greengard ◽  
Brenda Weigel ◽  
Logan Spector

Aim. To investigate prognostic factors in pediatric and young adult patients with localized osteosarcoma that could predict the development of subsequent pulmonary metastases and lead to an ability to risk-stratify therapy. We performed a systematic review of the literature published since January 1990 to establish common evidence-based prognostic factors. Methods. PubMed and Embase searches (Jan 1990–Aug 2018) were performed. Two reviewers independently selected papers for patients with localized osteosarcoma with subsequent metastatic development and then reviewed for quality of methods and prognostic factors. Results. Database searches yielded 216 unique results. After screening, 27 full-text articles were studied in depth, with 9 items fulfilling predetermined inclusion and exclusion criteria. Age, tumor location, tumor size/volume, and histologic response carried independent prognostic value in the majority of the studies. Conclusions. Several prognostic factors seemed to be consistent amongst the studies, but the heterogeneity and smaller sizes of the study populations made pooling of results difficult. Standardization of larger patient populations and consistent definitions/cutoffs for prognostic factors are needed to further assess for consistent prognostic factors and potential predictive models to be developed.


2017 ◽  
Vol 88 (1) ◽  
pp. 60-81
Author(s):  
Mimi Mehlsen ◽  
Mai Bjørnskov Mikkelsen ◽  
Christina Maar Andersen ◽  
Chaitali Ollars

Social and temporal comparisons may help the individual anchor his or her self-image in a social and temporal context. In the Life-Span Theory of Control, comparisons are included in the repertoire of secondary control strategies individuals may apply when primary control strategies are obstructed, for example, by age-related losses or physical decline. The aim of this study was to explore differences in prevalence and effects of social and temporal comparisons in younger and older adults and healthy and diseased individuals ( n = 34). Semistructured interviews were conducted and analyzed using a mixed-methods approach combining qualitative and quantitative data analysis. The results revealed that older adults engaged in more comparisons than younger adults and that the outcomes of comparisons were more positive for older adults, particularly older cancer patients. The results indicate that comparisons may be applied more often by older and diseased individuals in the service of maintaining well-being.


2013 ◽  
Vol 13 (4) ◽  
pp. 424-429 ◽  
Author(s):  
Beatrice Nardone ◽  
Shenhong Wu ◽  
Benjamin C. Garden ◽  
Dennis P. West ◽  
Lilian M. Reich ◽  
...  

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