Faculty Opinions recommendation of Randomized phase 2 study of GMI-1070 in SCD: reduction in time to resolution of vaso-occlusive events and decreased opioid use.

2015 ◽  
Author(s):  
Adlette Inati ◽  
Hussein Abbas
Keyword(s):  
Phase 2 ◽  
Opioid Use ◽  
Phase 2 Study ◽  
Randomized Phase 2

scholarly journals Randomized phase 2 study of GMI-1070 in SCD: reduction in time to resolution of vaso-occlusive events and decreased opioid use

Blood ◽  
2015 ◽  
Vol 125 (17) ◽  
pp. 2656-2664 ◽  
Author(s):  
Marilyn J. Telen ◽  
Ted Wun ◽  
Timothy L. McCavit ◽  
Laura M. De Castro ◽  
Lakshmanan Krishnamurti ◽  
...  
Keyword(s):  
Phase 2 ◽  
Opioid Use ◽  
Phase 3 ◽  
Phase 2 Study ◽  
Key Points ◽  
Randomized Phase 2

Key Points GMI-1070 led to statistically insignificant but large reductions in time to resolution of VOC and a significant reduction in opioid use. These results support a role for selectins in VOC and progression to a phase 3 study of GMI-1070 for SCD patients with vaso-occlusion.

scholarly journals ADAMANT: a placebo-controlled randomized phase 2 study of AADvac1, an active immunotherapy against pathological tau in Alzheimer’s disease

Nature Aging ◽  
2021 ◽  
Vol 1 (6) ◽  
pp. 521-534
Author(s):  
Petr Novak ◽  
Branislav Kovacech ◽  
Stanislav Katina ◽  
Reinhold Schmidt ◽  
Philip Scheltens ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Active Immunotherapy ◽  
Phase 2 ◽  
Phase 2 Study ◽  
Randomized Phase 2

scholarly journals Intra-articular CNTX-4975 for osteoarthritis knee pain: subgroup and post hoc analyses of a randomized phase 2 study

2019 ◽  
Vol 27 ◽  
pp. S499
Author(s):  
R.M. Stevens ◽  
J.N. Campbell ◽  
K. Guedes ◽  
V.H. Smith ◽  
P.D. Hanson ◽  
...  
Keyword(s):  
Knee Pain ◽  
Phase 2 ◽  
Phase 2 Study ◽  
Osteoarthritis Knee ◽  
Post Hoc ◽  
Randomized Phase 2

scholarly journals OP0109 EFFICACY OF FILGOTINIB VS PLACEBO IN ACTIVE PSORIATIC ARTHRITIS: PATIENT-LEVEL DATA FROM EQUATOR, A RANDOMIZED, PHASE 2 STUDY

2019 ◽  
Author(s):  
Philip J Mease ◽  
Dafna D Gladman ◽  
Filip van den Bosch ◽  
Mykola Stanislavchuk ◽  
Anna Rychlewska-Hanczewska ◽  
...  
Keyword(s):  
Psoriatic Arthritis ◽  
Phase 2 ◽  
Patient Level Data ◽  
Patient Level ◽  
Level Data ◽  
Phase 2 Study ◽  
Randomized Phase 2
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