Faculty Opinions recommendation of The Role of Posttraumatic Hypothermia in Preventing Dendrite Degeneration and Spine Loss after Severe Traumatic Brain Injury.

Author(s):  
W Dalton Dietrich
2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Chuan-fang Wang ◽  
Cheng-cheng Zhao ◽  
Gan Jiang ◽  
Xiao Gu ◽  
Jun-feng Feng ◽  
...  

2015 ◽  
Vol 2015 ◽  
pp. 1-7
Author(s):  
Lukas Kurt Postl ◽  
Viktoria Bogner ◽  
Martijn van Griensven ◽  
Marc Beirer ◽  
Karl Georg Kanz ◽  
...  

In traumatic brain injury (TBI) the analysis of neuroinflammatory mechanisms gained increasing interest. In this context certain immunocompetent cells might play an important role. Interestingly, in the actual literature there exist only a few studies focusing on the role of monocytes and granulocytes in TBI patients. In this regard it has recently reported that the choroid plexus represents an early, selective barrier for leukocytes after brain injury. Therefore the aim of this study was to evaluate the very early dynamics of CD14+ monocytes and CD15+ granulocyte in CSF of patients following severe TBI with regard to the integrity of the BBB. Cytometric flow analysis was performed to analyze the CD14+ monocyte and CD15+ granulocyte population in CSF of TBI patients. The ratio of CSF and serum albumin as a measure for the BBB’s integrity was assessed in parallel. CSF samples of patients receiving lumbar puncture for elective surgery were obtained as controls. Overall 15 patients following severe TBI were enrolled. 10 patients were examined as controls. In patients, the monocyte population as well as the granulocyte population was significantly increased within 72 hours after TBI. The BBB’s integrity did not have a significant influence on the cell count in the CSF.


2012 ◽  
Vol 414 ◽  
pp. 228-233 ◽  
Author(s):  
Ana Rodríguez-Rodríguez ◽  
Juan José Egea-Guerrero ◽  
Antonio León-Justel ◽  
Elena Gordillo-Escobar ◽  
Jaume Revuelto-Rey ◽  
...  

2020 ◽  
pp. 1-4

Abstract This case report demonstrated that electro-acupuncture treatment has improved the outcome of an adolescent with severe traumatic brain injury due to a traffic accident. The patient had a bilateral frontal hematoma, subdural hematoma, subarachnoid hemorrhage, stem hematoma and diffuse parenchymal swelling with the initial Glasgow Coma Scale score of E1V1M1. Daily electro-acupuncture therapy was prescribed with strong stimulation at GV 26 (Shuigou), PC6 (Neiguan) and EX-UE11(Shixuan) when the vital signs of the patient became stable. The patient had a full recovery of the consciousness in 30 days. The follow-up observation found that he has also restored the motor and speech functions. This result suggested a potential role of electro-acupuncture in the treatment of consciousness disturbance for patient with traumatic brain injury.


Sign in / Sign up

Export Citation Format

Share Document