Faculty Opinions recommendation of Effects of Combined Exposure to Chronic High-Fat Diet and Arsenic on Thyroid Function and Lipid Profile in Male Mouse.
Introduction: A high-fat diet and obesity, promoted by an unhealthy lifestyle, affect the structure of spermatozoa. The study aims to determine the effect of using purple eggplant on improving lipid profile and sperm quality as an alternative to traditional medicine of Rattus norvegicus.
To the best of our knowledge, this study firstly shows that soyasaponins (A1 & A2) exhibit antiatherosclerotic bioactivities by improving the serum lipid profile and reducing TLR4-/MyD88-/NF-κB-mediated inflammations in high fat diet-fed ApoE−/− mice.