scholarly journals Faculty Opinions recommendation of A Real-Time Biosensor for ERK Activity Reveals Signaling Dynamics during C. elegans Cell Fate Specification.

2017 ◽  
Author(s):  
Robert K Herman
Keyword(s):  
Real Time ◽  
Cell Fate ◽  
Cell Fate Specification ◽  
Fate Specification ◽  
C Elegans ◽  
Signaling Dynamics ◽  
Erk Activity

scholarly journals A Real-Time Biosensor for ERK Activity Reveals Signaling Dynamics during C. elegans Cell Fate Specification

2017 ◽  
Vol 42 (5) ◽  
pp. 542-553.e4 ◽  
Author(s):  
Claire de la Cova ◽  
Robert Townley ◽  
Sergi Regot ◽  
Iva Greenwald
Keyword(s):  
Real Time ◽  
Cell Fate ◽  
Cell Fate Specification ◽  
Fate Specification ◽  
C Elegans ◽  
Signaling Dynamics ◽  
Erk Activity

Genes necessary for C. elegans cell and growth cone migrations

Development ◽  
1997 ◽  
Vol 124 (9) ◽  
pp. 1831-1843 ◽  
Author(s):  
W.C. Forrester ◽  
G. Garriga
Keyword(s):  
Cell Fate ◽  
Single Gene ◽  
Growth Cones ◽  
Cell Fate Specification ◽  
Fate Specification ◽  
C Elegans ◽  
Final Destination ◽  
Multiple Cell

The migrations of cells and growth cones contribute to form and pattern during metazoan development. To study the mechanisms that regulate cell motility, we have screened for C. elegans mutants defective in the posteriorly directed migrations of the canal-associated neurons (CANs). Here we describe 14 genes necessary for CAN cell migration. Our characterization of the mutants has led to three conclusions. First, the mutations define three gene classes: genes necessary for cell fate specification, genes necessary for multiple cell migrations and a single gene necessary for final positioning of migrating cells. Second, cell interactions between the CAN and HSN, a neuron that migrates anteriorly to a position adjacent to the CAN, control the final destination of the HSN cell body. Third, C. elegans larval development requires the CANs. In the absence of CAN function, larvae arrest development, with excess fluid accumulating in their pseudocoeloms. This phenotype may reflect a role of the CANs in osmoregulation.

scholarly journals Transcriptional upregulation of the C. elegans Hox gene lin-39 during vulval cell fate specification

2006 ◽  
Vol 123 (2) ◽  
pp. 135-150 ◽  
Author(s):  
Javier A. Wagmaister ◽  
Julie E. Gleason ◽  
David M. Eisenmann
Keyword(s):  
Cell Fate ◽  
Cell Fate Specification ◽  
Hox Gene ◽  
Fate Specification ◽  
C Elegans

scholarly journals Mab21, the mouse homolog of a C. elegans cell-fate specification gene, participates in cerebellar, midbrain and eye development

1998 ◽  
Vol 79 (1-2) ◽  
pp. 131-135 ◽  
Author(s):  
M. Mariani ◽  
A. Corradi ◽  
D. Baldessari ◽  
N. Malgaretti ◽  
O. Pozzoli ◽  
...  
Keyword(s):  
Cell Fate ◽  
Eye Development ◽  
Cell Fate Specification ◽  
Mouse Homolog ◽  
Fate Specification ◽  
C Elegans
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