Faculty Opinions recommendation of Modulation of the gut microbiome: a systematic review of the effect of bariatric surgery.

2020 ◽  
Author(s):  
Eamonn Quigley
Keyword(s):  
Systematic Review ◽  
Bariatric Surgery ◽  
Gut Microbiome

scholarly journals Modulation of the gut microbiome: a systematic review of the effect of bariatric surgery

2018 ◽  
Vol 178 (1) ◽  
pp. 43-56 ◽  
Author(s):  
Yan Guo ◽  
Zhi-Ping Huang ◽  
Chao-Qian Liu ◽  
Lin Qi ◽  
Yuan Sheng ◽  
...  
Keyword(s):  
Systematic Review ◽  
Bariatric Surgery ◽  
Gut Microbiota ◽  
Strong Evidence ◽  
Gut Microbiome ◽  
Animal Experiments ◽  
Human Metabolism ◽  
Microbial Groups ◽  
Host Metabolism

Objective Bariatric surgery is recommended for patients with obesity and type 2 diabetes. Recent evidence suggested a strong connection between gut microbiota and bariatric surgery. Design Systematic review. Methods The PubMed and OVID EMBASE were used, and articles concerning bariatric surgery and gut microbiota were screened. The main outcome measures were alterations of gut microbiota after bariatric surgery and correlations between gut microbiota and host metabolism. We applied the system of evidence level to evaluate the alteration of microbiota. Modulation of short-chain fatty acid and gut genetic content was also investigated. Results Totally 12 animal experiments and 9 clinical studies were included. Based on strong evidence, 4 phyla (Bacteroidetes, Fusobacteria, Verrucomicrobia and Proteobacteria) increased after surgery; within the phylum Firmicutes, Lactobacillales and Enterococcus increased; and within the phylum Proteobacteria, Gammaproteobacteria, Enterobacteriales Enterobacteriaceae and several genera and species increased. Decreased microbial groups were Firmicutes, Clostridiales, Clostridiaceae, Blautia and Dorea. However, the change in microbial diversity is still under debate. Faecalibacterium prausnitzii, Lactobacillus and Coprococcus comes are implicated in many of the outcomes, including body composition and glucose homeostasis. Conclusions There is strong evidence to support a considerable alteration of the gut microbiome after bariatric surgery. Deeper investigations are required to confirm the mechanisms that link the gut microbiome and metabolic alterations in human metabolism.

Altered gut microbiome after bariatric surgery and its association with metabolic benefits: A systematic review

2019 ◽  
Vol 15 (4) ◽  
pp. 656-665 ◽  
Author(s):  
Naomi K. Davies ◽  
Justin M. O'Sullivan ◽  
Lindsay D. Plank ◽  
Rinki Murphy
Keyword(s):  
Systematic Review ◽  
Bariatric Surgery ◽  
Gut Microbiome

scholarly journals The Gut Microbiome Profile in Obesity: A Systematic Review

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Olga Castaner ◽  
Albert Goday ◽  
Yong-Moon Park ◽  
Seung-Hwan Lee ◽  
Faidon Magkos ◽  
...  
Keyword(s):  
Systematic Review ◽  
Bariatric Surgery ◽  
Weight Loss ◽  
Gut Microbiome ◽  
Metabolic Disorders ◽  
Current Evidence ◽  
Weight Loss Intervention ◽  
The Past ◽  
Microbiome Profile ◽  
Depth Study

Gut microbiome has been identified in the past decade as an important factor involved in obesity, but the magnitude of its contribution to obesity and its related comorbidities is still uncertain. Among the vast quantity of factors attributed to obesity, environmental, dietary, lifestyle, genetic, and others, the microbiome has aroused curiosity, and the scientific community has published many original articles. Most of the studies related to microbiome and obesity have been reported based on the associations between microbiota and obesity, and the in-depth study of the mechanisms related has been studied mainly in rodents and exceptionally in humans. Due to the quantity and diverse information published, the need of reviews is mandatory to recapitulate the relevant achievements. In this systematic review, we provide an overview of the current evidence on the association between intestinal microbiota and obesity. Additionally, we analyze the effects of an extreme weight loss intervention such as bariatric surgery on gut microbiota. The review is divided into 2 sections: first, the association of obesity and related metabolic disorders with different gut microbiome profiles, including metagenomics studies, and second, changes on gut microbiome after an extreme weight loss intervention such as bariatric surgery.

scholarly journals Hair Loss After Metabolic and Bariatric Surgery: a Systematic Review and Meta-analysis

2021 ◽  
Author(s):  
Wen Zhang ◽  
◽  
Meiling Fan ◽  
Cunchuan Wang ◽  
Kamal Mahawar ◽  
...  
Keyword(s):  
Systematic Review ◽  
Bariatric Surgery ◽  
Folic Acid ◽  
Hair Loss ◽  
Meta Analysis ◽  
Serum Zinc ◽  
Serum Levels ◽  
Mean Difference ◽  
Younger Women ◽  
Metabolic And Bariatric Surgery

Abstract Background Hair loss is a common complication after metabolic and bariatric surgery (MBS). There is a lack of published systematic review in the scientific literature on this topic. The aim of this study was to perform a systematic review and meta-analysis on hair loss after MBS in accordance with Preferred Reporting Items for Systematic reviews and Meta-Analysis (PRISMA) guidelines. Methods PubMed, CINAHL, EMBASE, Web of Science, SCOPUS, and four Chinese databases were searched. Data were pooled using Review Manager 5.3 and Stata 12.0, and subgroups were performed if necessary and feasible. Results A total of 18 studies (n = 2538) were included. The pooled results showed that the incidence of hair loss after MBS was 57% (95% CI 42–71%). It decreased with longer follow-up times. Hair loss was significantly more common in younger (mean difference (MD), − 2.45; 95% CI, − 4.26 to − 0.64; p = 0.008) women (OR, 3.87; 95% CI, 0.59 to 17.59; p = 0.08). Serum zinc (standardized mean difference (SMD), − 1.13; 95% CI, − 2.27 to 0.01, p = 0.05), folic acid (SMD = − 0.88, 95% CI − 1.29 to − 0.46, p < 0.0001), and ferritin levels (SMD, − 0.22; 95% CI, − 0.38 to − 0.05; p = 0.01), but not serum iron and vitamin B12, were associated with hair loss following MBS. Conclusions Hair loss is common after MBS especially in younger women, and those with low serum levels of zinc, folic acid, and ferritin. Prospective studies on larger cohorts are needed.

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