Faculty Opinions recommendation of A MORC-driven transcriptional switch controls Toxoplasma developmental trajectories and sexual commitment.

Author(s):  
Dominique Soldati ◽  
Aarti Krishnan
2020 ◽  
Vol 5 (4) ◽  
pp. 570-583 ◽  
Author(s):  
Dayana C. Farhat ◽  
Christopher Swale ◽  
Céline Dard ◽  
Dominique Cannella ◽  
Philippe Ortet ◽  
...  

2020 ◽  
Vol 63 (4) ◽  
pp. 1071-1082
Author(s):  
Theresa Schölderle ◽  
Elisabet Haas ◽  
Wolfram Ziegler

Purpose The aim of this study was to collect auditory-perceptual data on established symptom categories of dysarthria from typically developing children between 3 and 9 years of age, for the purpose of creating age norms for dysarthria assessment. Method One hundred forty-four typically developing children (3;0–9;11 [years;months], 72 girls and 72 boys) participated. We used a computer-based game specifically designed for this study to elicit sentence repetitions and spontaneous speech samples. Speech recordings were analyzed using the auditory-perceptual criteria of the Bogenhausen Dysarthria Scales, a standardized German assessment tool for dysarthria in adults. The Bogenhausen Dysarthria Scales (scales and features) cover clinically relevant dimensions of speech and allow for an evaluation of well-established symptom categories of dysarthria. Results The typically developing children exhibited a number of speech characteristics overlapping with established symptom categories of dysarthria (e.g., breathy voice, frequent inspirations, reduced articulatory precision, decreased articulation rate). Substantial progress was observed between 3 and 9 years of age, but with different developmental trajectories across different dimensions. In several areas (e.g., respiration, voice quality), 9-year-olds still presented with salient developmental speech characteristics, while in other dimensions (e.g., prosodic modulation), features typically associated with dysarthria occurred only exceptionally, even in the 3-year-olds. Conclusions The acquisition of speech motor functions is a prolonged process not yet completed with 9 years. Various developmental influences (e.g., anatomic–physiological changes) shape children's speech specifically. Our findings are a first step toward establishing auditory-perceptual norms for dysarthria in children of kindergarten and elementary school age. Supplemental Material https://doi.org/10.23641/asha.12133380


2003 ◽  
Author(s):  
J. L. Aber ◽  
◽  
J. L. Brown ◽  
S. M. Jones ◽  
P. A. Brennan ◽  
...  

2008 ◽  
Author(s):  
D. M. Costello ◽  
J. Swendsen ◽  
J. S. Rose ◽  
L. C. Dierker

2012 ◽  
Author(s):  
Joel G. Simons ◽  
Brian A. Baynes ◽  
Wayne V. Adams

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